Ajiboye BO, Oloyede HO, Salawu MO (2018) Antihyperglycemic and antidyslipidemic activity of Musa paradisiaca-based diet in alloxan-induced diabetic rats. Food Sci Nutr 6(1):137–145
Article
CAS
PubMed
Google Scholar
Akhtar N, Akram M, Daniyal M, Ahmad S (2018) Evaluation of antidiabetic activity of Ipomoea batatas L. extract in alloxan-induced diabetic rats. Int J Immunopathol Pharmacol 32:1–6. https://doi.org/10.1177/2058738418814678
Article
CAS
Google Scholar
Alam MN, Bristi NJ, Rafiquzzaman M (2013) Review on in vivo and in vitro methods evaluation of antioxidant activity. Saudi Pharm J 21(2):143–152. https://doi.org/10.1016/j.jsps.2012.05.002
Article
PubMed
Google Scholar
Arun KB, Jayamurthy P, Anusha CV, Mahesh SK, Nisha P (2017) Studies on activity guided fractionation of pomegranate peel extracts and its effect on antidiabetic and cardiovascular protection properties. J Food Process Preserv 41(1):e13108. https://doi.org/10.1111/jfpp.13108
Article
CAS
Google Scholar
Babu S, Jayaraman S (2020) An update on β-sitosterol: a potential herbal nutraceutical for diabetic management. Biomed Pharmacother 131:110702. https://doi.org/10.1016/j.biopha.2020.110702
Article
CAS
PubMed
Google Scholar
Bhat ZA, Ansari SH, Mukhtar HM, Naved T, Khan NA, Chashoo IA (2005) Anti-hyperglycemic activity of the alcoholic extracts of Aralia cachemirica Decneroota. J Nat Rem 5:160–164
Google Scholar
Boligon AA, Machado MM, Athayde ML (2014) Technical evaluation of antioxidant activity. Med Chem 4(7):517–522. https://doi.org/10.22377/ijgp.v12i03.2025
Article
Google Scholar
Boyce-Rustay JM, Jarvis MF (2009) Neuropathic pain: models and mechanisms. Curr Pharm Des 15(15):1711–1716
Article
CAS
PubMed
Google Scholar
Brand-Williams W, Cuvelier ME, Berset CLWT (1995) Use of a free radical method to evaluate antioxidant activity. LWT Food Sci Technol 28(1):25–30. https://doi.org/10.1016/S0023-6438(95)80008-5
Article
CAS
Google Scholar
Carroll NV, Longley RW, Roe JH (1956) The determination of glycogen in liver and muscle by use of anthrone reagent. J Biol Chem 220(2):583–593
Article
CAS
PubMed
Google Scholar
Chika A, Bello SO (2010) Antihyperglycemic activity of aqueous leaf extract of Combretum micranthum (Combretaceae) in normal and alloxan-induced diabetic rats. J Ethnopharmacol 129(1):34–37. https://doi.org/10.1016/j.jep.2010.02.008
Article
PubMed
Google Scholar
Chinsembu KC (2019) Diabetes mellitus and nature’s pharmacy of putative antidiabetic plants. J Herb Med 15:100230
Article
Google Scholar
Chunhakant S, Chaicharoenpong C (2019) Antityrosinase, antioxidant, and cytotoxic activities of phytochemical constituents from Manilkara zapota L. Bark. Molecules 24(15):2798
Article
PubMed Central
Google Scholar
Crespo MJ, Zalacaín J, Dunbar DC, Cruz N, Arocho L (2008) Cardiac oxidative stress is elevated at the onset of dilated cardiomyopathy in streptozotocin-diabetic rats. J Cardiovasc Pharmacol Ther 13(1):64–71
Article
CAS
PubMed
Google Scholar
Dra LA, Sellami S, Rais H, Aziz F, Aghraz A, Bekkouche K, Larhsini M (2019) Antidiabetic potential of Caralluma europaea against alloxan-induced diabetes in mice. Saudi J Biol Sci 26(6):1171–1178
Article
CAS
PubMed
Google Scholar
Duong TH, Trung NT, Phan CTD, Nguyen VK, Musa V, Ruksilp T, Sichaem J (2020) Manilkzapotane, a novel dimeric alkylresorcinol derivative from the stem bark of Manilkara zapota. J Asian Nat Prod Res 23:1–7
Google Scholar
Eawsakul K, Panichayupakaranant P, Ongtanasup T, Warinhomhoun S, Noonong K, Bunluepuech K (2021) Computational study and in vitro alpha-glucosidase inhibitory effects of medicinal plants from a Thai folk remedy. Heliyon 7(9):e08078. https://doi.org/10.1016/j.heliyon.2021.e08078
Article
PubMed
PubMed Central
Google Scholar
Eliza J, Daisy P, Ignacimuthu S, Duraipandiyan V (2009) Antidiabetic and antilipidemic effect of eremanthin from Costus speciosus (Koen.) Sm., in STZ-induced diabetic rats. Chem Biol Interact 182(1):67–72. https://doi.org/10.1016/j.cbi.2009.08.012
Article
CAS
PubMed
Google Scholar
Elshemy MA (2018) Antidiabetic and anti-hyperlipidemic effects of virgin coconut oil in rats. Egypt J Vet Sci 49(2):111–117. https://doi.org/10.21608/ejvs.2018.3548.1036
Article
Google Scholar
Fujisawa T, Ikegami H, Inoue K, Kawabata Y, Ogihara T (2005) Effect of two αglucosidase inhibitors, voglibose and acarbose, on postprandial hyperglycemia correlates with subjective abdominal symptoms. Metabolism 54:387–390
Article
CAS
PubMed
Google Scholar
Ghani A (1998) Medicinal plants of Bangladesh: chemical constituents and uses. Asiatic Society of Bangladesh, Dhaka
Google Scholar
Ghosh J, Sil PC (2013) Arjunolic acid: a new multifunctional therapeutic promise of alternative medicine. Biochimie 95(6):1098–1109. https://doi.org/10.1016/j.biochi.2013.01.016
Article
CAS
PubMed
Google Scholar
Gomathy K, Baskar R, Kumaresan K (2013) Comparison of antioxidant potential in pulp and peel extracts of Manilkara zapota (L.) P. Royen. Afr J Biotech 12(31):4936–4943. https://doi.org/10.5897/AJB2012.2961
Article
CAS
Google Scholar
Grover JK, Vats V, Yadav S (2002) Effect of feeding aqueous extract of Pterocarpus marsupium on glycogen content of tissues and the key enzymes of carbohydrate metabolism. Mol Cell Biochem 241(1):53–59
Article
CAS
PubMed
Google Scholar
Gupta R, Sharma AK, Sharma MC, Dobhal MP, Gupta RS (2012) Evaluation of antidiabetic and antioxidant potential of lupeol in experimental hyperglycaemia. Nat Prod Res 26(12):1125–1129
Article
CAS
PubMed
Google Scholar
Gurupriya S, Cathrine L, Ramesh J (2018) In vitro antidiabetic and antioxidant activities of lupeol isolated from the methanolic extract of Andrographis echioides leaves. J Pharmacogn Phytochem 7(4):768–775
CAS
Google Scholar
Halliwell B, Clement MV, Long LH (2000) Hydrogen peroxide in the human body. FEBS Lett 486(1):10–13. https://doi.org/10.1016/S0014-5793(00)02197-9
Article
CAS
PubMed
Google Scholar
Hilma R, Herliani H, Almurdani M (2018) Determination of total phenolic, flavonoid content and free radical scavenging activity of ethanol extract Sawo stem bark (Manilkara Zapota (L.)). Pros CELSciTech 3:62–68
Google Scholar
Ibrahim MA, Islam MS (2014) Anti-diabetic effects of the acetone fraction of Senna singueana stem bark in a type 2 diabetes rat model. J Ethnopharmacol 153(2):392–399
Article
PubMed
Google Scholar
International Diabetes Federation (IDF) (2011) Diabetes Atlas, 5th edn. International Diabetes Federation, Brussels, Belgium
Google Scholar
Iwaki M, Matsuda M, Maeda N, Funahashi T, Matsuzawa Y, Makishima M, Shimomura I (2003) Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors. Diabetes 52(7):1655–1663
Article
CAS
PubMed
Google Scholar
Jing L, Ma H, Fan P, Gao R, Jia Z (2015) Antioxidant potential, total phenolic and total flavonoid contents of Rhododendron anthopogonoides and its protective effect on hypoxia-induced injury in PC12 cells. BMC Complement Altern Med 15(1):1–12. https://doi.org/10.1186/s12906-015-0820-3
Article
CAS
Google Scholar
Kaneria M, Baravalia Y, Vaghasiya Y, Chanda S (2009) Determination of antibacterial and antioxidant potential of some medicinal plants from Saurashtra region, India. Indian J Pharm Sci 2009(71):406
Google Scholar
Kang MJ, Lee EK, Lee SS (2004) Effects of two P/S ratios with same peroxidizability index value and antioxidants supplementation on serum lipid concentration and hepatic enzyme activities of rats. Clin Chim Acta 350(1–2):79–87. https://doi.org/10.1016/j.cccn.2004.07.005
Article
CAS
PubMed
Google Scholar
Karle PP, Dhawale SC, Navghare VV, Shivpuje SS (2021) Optimization of extraction conditions and evaluation of Manilkara zapota (L.) P. Royen fruit peel extract for in vitro α-glucosidase enzyme inhibition and free radical scavenging potential. Future J Pharm Sci 7(1):1–10
Google Scholar
Khandelwal K (2008) Practical pharmacognosy. Pragati Books Pvt Ltd, Pune
Google Scholar
Khanra R, Bhattacharjee N, Dua TK, Nandy A, Saha A, Kalita J, Dewanjee S (2017) Taraxerol, a pentacyclic triterpenoid, from Abroma augusta leaf attenuates diabetic nephropathy in type 2 diabetic rats. Biomed Pharmacother 94:726–741. https://doi.org/10.1016/j.biopha.2017.07.112
Article
CAS
PubMed
Google Scholar
Kishore L, Kajal A, Kaur N (2017) Role of nicotinamide in streptozotocin induced diabetes in animal models. J Endocrinol Thyroid Res 2(1):555–577. https://doi.org/10.19080/JETR.2017.02.555577
Article
Google Scholar
Kole L, Sarkar M, Deb A, Giri B (2016) Pioglitazone, an anti-diabetic drug requires sustained MAPK activation for its anti-tumor activity in MCF7 breast cancer cells, independent of PPAR-γ pathway. Pharmacol Rep 68(1):144–154
Article
CAS
PubMed
Google Scholar
Kumar A, Sahoo HB (2020a) Preliminary pharmacological evaluation of stems bark extract for Manilkara zapota ulcerative colitis in rats. Adv Pharm J 5(4):144–148
Article
CAS
Google Scholar
Kumar D, Kumar S, Kohli S, Arya R, Gupta J (2011) Antidiabetic activity of methanolic bark extract of Albizia odoratissima Benth. in alloxan induced diabetic albino mice. Asian Pac J Trop Med 4(11):900–903
Article
PubMed
Google Scholar
Kumar S, Kumar V, Prakash O (2013) Enzymes inhibition and antidiabetic effect of isolated constituents from Dillenia indica. BioMed Res Int 2013:1–7
Google Scholar
Kumar DA, Anusha SV, Oruganti S, Deshpande M, Zehra A, Tiwari AK (2015) Raw versus cooked vegetable juice. Nutrafoods 14(1):27–38
Article
CAS
Google Scholar
Latha RC, Daisy P (2011) Insulin-secretagogue, antihyperlipidemic and other protective effects of gallic acid isolated from Terminalia bellerica Roxb. in streptozotocin-induced diabetic rats. Chem Biol Interact 189(1–2):112–118. https://doi.org/10.1016/j.cbi.2010.11.005
Article
CAS
PubMed
Google Scholar
Lee G, Goosens KA (2015) Sampling blood from the lateral tail vein of the rat. JoVE (j vis Exp) 99:e52766. https://doi.org/10.3791/52766
Article
Google Scholar
Lee YJ, Kim EO, Choi SW (2011) Isolation and identification of antioxidant polyphenolic compounds in mulberry (Morus alba L.) seeds. J Korean Soc Food Sci Nutr 40(4):517–524
Article
CAS
ADS
Google Scholar
Ma J, Luo XD, Protiva P, Yang H, Ma C, Basile MJ, Kennelly EJ (2003) Bioactive novel polyphenols from the fruit of Manilkara zapota (Sapodilla). J Nat Prod 66(7):983–986. https://doi.org/10.1021/np020576x
Article
CAS
PubMed
Google Scholar
Macdonald Ighodaro O, Mohammed Adeosun A, Adeboye Akinloye O (2017) Alloxan-induced diabetes, a common model for evaluating the glycemic-control potential of therapeutic compounds and plants extracts in experimental studies. Medicina 53(6):365–374. https://doi.org/10.1016/j.medici.2018.02.001
Article
PubMed
Google Scholar
Maniyar Y, Bhixavatimath P (2012) Antihyperglycemic and hypolipidemic activities of aqueous extract of Carica papaya Linn. leaves in alloxan-induced diabetic rats. J Ayurveda Integr Med 3(2):70. https://doi.org/10.4103/0975-9476.96519
Article
PubMed
PubMed Central
Google Scholar
Manna P, Sil PC (2012) Impaired redox signaling and mitochondrial uncoupling contributes vascular inflammation and cardiac dysfunction in type 1 diabetes: protective role of arjunolic acid. Biochimie 94(3):786–797
Article
CAS
PubMed
Google Scholar
Meier C, Schwartz AV, Egger A, Lecka-Czernik B (2016) Effects of diabetes drugs on the skeleton. Bone 82:93–100
Article
CAS
PubMed
Google Scholar
Mohiddin YBH, Chin W, Worth DH (1992) Traditional medicinal plants of Brunei Darussalam part III. Sengkurong. Int J Pharmacogn 30(2):105–108. https://doi.org/10.3109/13880209209053967
Article
Google Scholar
Muhtadi Primarianti AU, Sujono TA (2015) Antidiabetic activity of durian (Durio zibethinus Murr.) and rambutan (Nephelium lappaceum L.) fruit peels in alloxan diabetic rats. Procedia Food Sci 3:255–261
Article
Google Scholar
Munhoz A, Frode TS (2018) Isolated compounds from natural products with potential antidiabetic activity-a systematic review. Curr Diabetes Rev 14(1):36–106
CAS
PubMed
Google Scholar
Musabayane CT (2012) The effects of medicinal plants on renal function and blood pressure in diabetes mellitus. Cardiovasc J S Afr 23:462–468
Article
CAS
Google Scholar
Nadig PD, Revankar RR, Dethe SM, Narayanswamy SB, Aliyar MA (2012) Effect of Tinospora cordifolia on experimental diabetic neuropathy. Indian J Pharmacol 44:580
Article
PubMed
PubMed Central
Google Scholar
Nagarajan NS, Murugesh N, Kumaresan PT, Radha N, Murali A (2005) Antidiabetic and antihyperlipemic effects of Clemeo felina. Fitoterapia 76(34):310–315. https://doi.org/10.1016/j.fitote.2005.03.020
Article
CAS
PubMed
Google Scholar
Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R, Zinman B (2009) American Diabetes Association, European Association for Study of Diabetes. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 32:193–203
Article
CAS
PubMed
PubMed Central
Google Scholar
Nkobole N, Bodede O, Hussein AA, Prinsloo G (2021) In vitro α-glucosidase and α-amylase activities of wild and cultivated Amaranthus spp. and isolated compounds. Pharmacogn J 13(6):1614–1620
Article
CAS
Google Scholar
Noor S, Prodhan A, Zohora FT, Tareq FS, Ahsan M, Hasan CM, Islam SN (2014) Phytochemical, antioxidant, antimicrobial, thrombolytic as well as cytotoxic studies on the stem bark of Manilkara zapota (sapotaceae). Asian J Chem 26(18):6138
Article
CAS
Google Scholar
Osman MA, Rashid MM, Aziz MA, Habib MR (2011) Inhibition of Ehrlich ascites carcinoma by Manilkara zapota L. stem bark in Swiss albino mice. Asian Pac J Trop Biomed 1(6):448–451
Article
PubMed
PubMed Central
Google Scholar
Quine SD, Raghu PS (2005) Effects of (-)-epicatechin, a flavonoid on lipid peroxidation and antioxidants in streptozotocin-induced diabetic liver, kidney and heart. Pharmacol Rep 57(5):610–615
CAS
PubMed
Google Scholar
Ramkumar KM, Vanitha P, Uma C, Suganya N, Bhakkiyalakshmi E, Sujatha J (2011) Antidiabetic activity of alcoholic stem extract of Gymnema montanum in streptozotocin-induced diabetic rats. Food Chem Toxicol 49(12):3390–3394. https://doi.org/10.1016/j.fct.2011.09.027
Article
CAS
PubMed
Google Scholar
Ramu R, Shirahatti PS, Nayakavadi S, Vadivelan R, Zameer F, Dhananjaya BL, Prasad N (2016) The effect of a plant extract enriched in stigmasterol and β-sitosterol on glycaemic status and glucose metabolism in alloxan-induced diabetic rats. Food Funct 7(9):3999–4011
Article
CAS
PubMed
Google Scholar
Ramya S, Narayanan V, Ponnerulan B, Saminathan E, Veeranan U (2020) Potential of peel extracts of Punica granatum and Citrus aurantifolia on alloxan-induced diabetic rats. Beni-Suef Univ J Basic Appl Sci 9(1):1–11
Article
Google Scholar
Rees DA, Alcolado JC (2005) Animal models of diabetes mellitus. Diabet Med 22(4):359–370
Article
CAS
PubMed
Google Scholar
Ruch RJ, Cheng SJ, Klaunig JE (1989) Prevention of cytotoxicity and inhibition of intercellular communication by antioxidant catechins isolated from Chinese green tea. Carcinogenesis 10(6):1003–1008. https://doi.org/10.1093/carcin/10.6.1003
Article
CAS
PubMed
Google Scholar
Saltos MBV, Puente BFN, Faraone I, Milella L, De Tommasi N, Braca A (2015) Inhibitors of α-amylase and α-glucosidase from Andromachia igniaria Humb. & Bonpl. Phytochem Lett 14:45–50
Article
CAS
Google Scholar
Savikin K, Zivkovic J, Alimpic A, Zdunic G, Jankovic T, Duletic-Lausevic S, Menkovic N (2018) Activity guided fractionation of pomegranate extract and its antioxidant, antidiabetic and antineurodegenerative properties. Ind Crops Prod 113:142–149
Article
CAS
Google Scholar
Shah SK, Jhade DN (2018) Evaluation of antifertility potential of Piper betle (Petiole) on female Wistar rats “rising approaches of herbal contraception’’. Biochem Biophys Rep 15:97–102. https://doi.org/10.1016/j.bbrep.2018.08.001
Article
PubMed
PubMed Central
Google Scholar
Shirwaikar A, Rajendran K, Barik R (2006) Effect of aqueous bark extract of Garuga pinnata Roxd. in streptozotocin-nicotinamide induced type-II diabetes mellitus. J Ethnopharmacol 107:285–290
Article
PubMed
Google Scholar
Smith DC (2013) Methods of euthanasia and disposal of laboratory animals. Methods Anim Exp 1:167–195
Google Scholar
Soussi A, Gargouri M, ElFeki A (2018) Effects of co-exposure to lead and zinc on redox status, kidney variables, and histopathology in adult albino rats. Toxicol Ind Health 34(7):469–480. https://doi.org/10.1177/0748233718770293
Article
CAS
PubMed
Google Scholar
Srisurichan S, Pornpakakul S (2015) Triterpenoids from the seedpods of Holarrhena curtisii King and Gamble. Phytochem Lett 12:282–286
Article
CAS
Google Scholar
Tawakoli M, Mojadidi M, Fadavi H, Malik RA (2012) Pathophysiology and treatment of painful diabetic neuropathy. Curr Pain Headache Rep 3:192–197
Google Scholar
Toze FAA, Fomani M, Nouga AB, Chouna JR, Waffo AFK, Wansi JD (2015) Taraxastane and lupane triterpenoids from the bark of Manilkara zapota. Int Res J Pure Appl Chem 7:157–164
Article
CAS
Google Scholar
Venkatesan T, Choi YW, Kim YK (2019) Impact of different extraction solvents on phenolic content and antioxidant potential of Pinus densiflora bark extract. BioMed Res Int 2019:1–14
Article
CAS
Google Scholar
Wan LS, Min QX, Wang YL, Yue YD, Chen JC (2013) Xanthone glycoside constituents of Swertia kouitchensis with α-glucosidase inhibitory activity. J Nat Prod 76(7):1248–1253. https://doi.org/10.1021/np400082g
Article
CAS
PubMed
Google Scholar
Wang Y, Xiang L, Wang C, Tang C, He X (2013) Antidiabetic and antioxidant effects and phytochemicals of mulberry fruit (Morus alba L.) polyphenol enhanced extract. PLoS ONE 8(7):e71144
Article
CAS
ADS
PubMed
PubMed Central
Google Scholar
Wang J, Huang M, Yang J, Ma X, Zheng S, Deng S, Zhao P (2017) Anti-diabetic activity of stigmasterol from soybean oil by targeting the GLUT4 glucose transporter. Food Nutr Res 61(1):1364117
Article
CAS
PubMed
PubMed Central
Google Scholar
Wen X-A, Liu J, Zhang LY, Ni P-Z, Sun H-B (2010) Synthesis and biological evaluation of arjunolic acid, bayogenin, hederagonic acid and 4-epi-hederagonic acid as glycogen phosphorylase inhibitors. Chin J Nat Med 8(6):441–448. https://doi.org/10.1016/S1875-5364(11)60006-X
Article
CAS
Google Scholar
Withouck H, Boeykens A, Broucke MV, Moreira MM, Delerue-Matos C, De Cooman L (2019) Evaluation of the impact of pre-treatment and extraction conditions on the polyphenolic profile and antioxidant activity of Belgium apple wood. Eur Food Res Technol 245(11):2565–2578
Article
CAS
Google Scholar
Xu F, Wu H, Wang X, Yang Y, Wang Y, Qian H, Zhang Y (2014) RP-HPLC characterization of lupenone and β-sitosterol in Rhizoma musae and evaluation of the anti-diabetic activity of lupenone in diabetic Sprague-Dawley rats. Molecules 19(9):14114–14127
Article
CAS
PubMed
PubMed Central
Google Scholar