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Table 3 α-glucosidase enzyme inhibition (%) by MZSB extracts

From: Screening of Manilkara zapota (L) P. Royen stem bark ethanolic extract for in vitro α-glucosidase inhibition, preliminary antidiabetic effects, and improvement of diabetes and its complications in alloxan-induced diabetes in Wistar rats

Concentration (µg/mL) Acarbose EMZSB AEMZSB
% Inhibition IC50 % Inhibition IC50 % Inhibition IC50
25 9.82 ± 0.82 86.43 ± 1.26 µg mL−1 6.14 ± 0.79 119.79 ± 1.52 µg mL−1 4.43 ± 0.12 129.92 ± 2.29 µg mL−1
50 22.76 ± 1.12   14.53 ± 0.93   12.94 ± 0.28  
75 42.68 ± 0.92   28.41 ± 0.87   25.72 ± 0.76  
100 57.48 ± 1.23   39.43 ± 0.88   33.95 ± 1.18  
125 78.83 ± 1.67   52.61 ± 0.9   48.59 ± 0.92  
150 95.24 ± 1.35   63.58 ± 1.05   59.67 ± 0.85  
  1. Values presented were mean ± SD of three replicate values