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Table 8 Serum lipid profile in alloxan-induced diabetic rats when treated with EMZSB for 21 days

From: Screening of Manilkara zapota (L) P. Royen stem bark ethanolic extract for in vitro α-glucosidase inhibition, preliminary antidiabetic effects, and improvement of diabetes and its complications in alloxan-induced diabetes in Wistar rats

Groups Serum HDL (mg dL−1) Serum LDL (mg dL−1) Serum cholesterol (mg dL−1) Serum triglyceride (mg dL−1)
Normal control 78.18 ± 4.08 49.66 ± 2.09 88.56 ± 4.28 111.73 ± 8.27
Diabetic control 46.77 ± 3.48$ 77.75 ± 3.69$ 170.92 ± 6.38# 165.92 ± 7.67#
Diabetic + Glimepiride 75.94 ± 1.82** 50.07 ± 1.18** 141.64 ± 6.91** 130.23 ± 6.84***
Diabetic + EMZSB 150 68.59 ± 1.88 60.54 ± 2.47 176.14 ± 4.28 163.49 ± 7.51
Diabetic + EMZSB 200 69.98 ± 1.46 55.32 ± 3.59 152.38 ± 3.05 144.27 ± 3.34
Diabetic + EMZSB 250 71.63 ± 2.84* 53.24 ± 2.08* 146.67 ± 4.29* 140.68 ± 5.46*
  1. Values were presented as mean ± SEM (n = 6); statistics employed was two-way ANOVA followed by Tukey's multiple comparison test. $p < 0.01, and #p < 0.001 when compared with normal control; *p < 0.05, **p < 0.01, and ***p < 0.001 when compared with diabetic control