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Table 11 Assessment of cardiovascular risk indices in alloxan-induced diabetic rats when treated with EMZSB

From: Screening of Manilkara zapota (L) P. Royen stem bark ethanolic extract for in vitro α-glucosidase inhibition, preliminary antidiabetic effects, and improvement of diabetes and its complications in alloxan-induced diabetes in Wistar rats

Groups

Cardiovascular risk indices (mg dl−1)

Coronary artery index

Cardiac index

Atherogenic index

Normal control

0.635 ± 0.10

1.132 ± 0.24

0.770 ± 0.08

Diabetic control

1.662 ± 0.18$

3.654 ± 1.16$

4.311 ± 0.58#

Diabetic + Glimepiride

0.659 ± 0.10*

1.865 ± 0.94*

0.740 ± 0.38**

Diabetic + EMZSB 150

0.882 ± 0.14

2.568 ± 0.72

4.268 ± 0.82

Diabetic + EMZSB 200

0.790 ± 0.13

2.177 ± 0.38

3.867 ± 0.48

Diabetic + EMZSB 250

0.743 ± 0.12*

2.047 ± 0.67*

1.543 ± 0.56*

  1. Values were presented as mean ± SEM (n = 6); statistics employed was two-way ANOVA followed by Tukey's multiple comparison test. $p < 0.05, #p < 0.01 when compared with normal control; *p < 0.05, **p < 0.01 when compared with diabetic control