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Table 11 Assessment of cardiovascular risk indices in alloxan-induced diabetic rats when treated with EMZSB

From: Screening of Manilkara zapota (L) P. Royen stem bark ethanolic extract for in vitro α-glucosidase inhibition, preliminary antidiabetic effects, and improvement of diabetes and its complications in alloxan-induced diabetes in Wistar rats

Groups Cardiovascular risk indices (mg dl−1)
Coronary artery index Cardiac index Atherogenic index
Normal control 0.635 ± 0.10 1.132 ± 0.24 0.770 ± 0.08
Diabetic control 1.662 ± 0.18$ 3.654 ± 1.16$ 4.311 ± 0.58#
Diabetic + Glimepiride 0.659 ± 0.10* 1.865 ± 0.94* 0.740 ± 0.38**
Diabetic + EMZSB 150 0.882 ± 0.14 2.568 ± 0.72 4.268 ± 0.82
Diabetic + EMZSB 200 0.790 ± 0.13 2.177 ± 0.38 3.867 ± 0.48
Diabetic + EMZSB 250 0.743 ± 0.12* 2.047 ± 0.67* 1.543 ± 0.56*
  1. Values were presented as mean ± SEM (n = 6); statistics employed was two-way ANOVA followed by Tukey's multiple comparison test. $p < 0.05, #p < 0.01 when compared with normal control; *p < 0.05, **p < 0.01 when compared with diabetic control