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Table 7 Body weights changes in alloxan-induced diabetic rats when treated with EMZSB during 21 days treatment

From: Screening of Manilkara zapota (L) P. Royen stem bark ethanolic extract for in vitro α-glucosidase inhibition, preliminary antidiabetic effects, and improvement of diabetes and its complications in alloxan-induced diabetes in Wistar rats

Groups Body weight changes (g)
7th day 14th day 21st day
Normal control 04.58 ± 2.15 6.47 ± 1.58 5.28 ± 2.78
Diabetic control − 11.98 ± 4.84$ − 11.28 ± 3.64$ − 12.72 ± 4.38$
Diabetic + Glimepiride 2.28 ± 2.05 5.58 ± 2.68* 7.95 ± 2.45**
Diabetic + EMZSB 150 − 6.67 ± 2.08 − 4.72 ± 3.68 − 4.23 ± 1.61
Diabetic + EMZSB 200 − 5.88 ± 2.29 − 1.73 ± 2.86 3.55 ± 4.77*
Diabetic + EMZSB 250 − 2.54 ± 1.19 5.27 ± 3.89* 6.93 ± 4.83**
  1. Values were presented as mean ± SEM (n = 6), statistics employed was two-way ANOVA followed by Tukey's multiple comparison test. $p < 0.05 when compared with normal control; *p < 0.05, **p < 0.01 when compared with diabetic control. Diabetic rats treated with EMZSB 250 mg kg−1 showed a significant bodyweight gain at the end of study