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Bulletin of the National Research Centre

Table 12 Assessment of EMZSB on hot plate-induced neuropathic pain in diabetic rats

From: Screening of Manilkara zapota (L) P. Royen stem bark ethanolic extract for in vitro α-glucosidase inhibition, preliminary antidiabetic effects, and improvement of diabetes and its complications in alloxan-induced diabetes in Wistar rats

Groups

Foot licking response(s)

Normal control

5.1 ± 0.7

Diabetic control

9.2 ± 0.4$

Diabetic + Glimepiride

6.9 ± 0.3*

Diabetic + EMZSB 150

9.1 ± 0.4ns

Diabetic + EMZSB 200

8.8 ± 0.4ns

Diabetic + EMZSB 250

8.2 ± 0.3ns

  1. Values were presented as mean ± SEM of two readings (n = 6); statistics employed was one-way ANOVA followed by Tukey’s test. $p < 0.001 when compared with normal control; *p < 0.05, ns (non-significant) when compared with diabetic control
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