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Table 12 Assessment of EMZSB on hot plate-induced neuropathic pain in diabetic rats

From: Screening of Manilkara zapota (L) P. Royen stem bark ethanolic extract for in vitro α-glucosidase inhibition, preliminary antidiabetic effects, and improvement of diabetes and its complications in alloxan-induced diabetes in Wistar rats

Groups Foot licking response(s)
Normal control 5.1 ± 0.7
Diabetic control 9.2 ± 0.4$
Diabetic + Glimepiride 6.9 ± 0.3*
Diabetic + EMZSB 150 9.1 ± 0.4ns
Diabetic + EMZSB 200 8.8 ± 0.4ns
Diabetic + EMZSB 250 8.2 ± 0.3ns
  1. Values were presented as mean ± SEM of two readings (n = 6); statistics employed was one-way ANOVA followed by Tukey’s test. $p < 0.001 when compared with normal control; *p < 0.05, ns (non-significant) when compared with diabetic control