Skip to main content
Bulletin of the National Research Centre

Table 9 Assessment of kidney parameters in alloxan-induced diabetic rats after 21 days treatment of EMZSB

From: Screening of Manilkara zapota (L) P. Royen stem bark ethanolic extract for in vitro α-glucosidase inhibition, preliminary antidiabetic effects, and improvement of diabetes and its complications in alloxan-induced diabetes in Wistar rats

Groups

Serum creatinine (mg dl−1)

Serum albumin (g dl−1)

Serum total protein (g dl−1)

Normal control

0.90 ± 0.67

5.67 ± 0.82

6.56 ± 0.38

Diabetic control

4.31 ± 0.42$

2.36 ± 0.42$

2.68 ± 0.68#

Diabetic + Glimepiride

1.00 ± 0.24*

5.60 ± 0.64*

5.93 ± 0.82*

Diabetic + EMZSB 150

3.58 ± 0.46

2.87 ± 0.28

3.14 ± 0.68

Diabetic + EMZSB 200

2.11 ± 0.67

4.68 ± 0.63

4.57 ± 0.92

Diabetic + EMZSB 250

1.20 ± 0.75*

5.48 ± 0.75*

5.85 ± 0.37*

  1. Values were presented as mean ± SEM. (n = 6); statistics employed was two-way ANOVA followed by Tukey's multiple comparison test. $p < 0.05, #p < 0.01 when compared with normal control; *p < 0.05 when compared with diabetic control
Back to article page