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Molecular Biology and Biotechnology

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  1. This study evaluated the effects of chitosan nanoparticles (Ch-NPs) on indoxacarb (INDOX)-induced pulmonary fibrosis in in vivo and in vitro models. In in vivo studies, 40 male albino rats were randomly divide...

    Authors: Naglaa A. Ali, Mohamed S. Kishta, Mohamed Fekry and Safaa H. Mohamed
    Citation: Bulletin of the National Research Centre 2022 46:274
  2. With regard to the extensive production of genetically modified organisms, scientists focused on the safety of antibiotic resistance marker (ARM) genes present in GM-crops produced for the consumption of human...

    Authors: Hanaa Abdel-Sadek Oraby, Nadia Aboul-Ftooh Aboul-Maaty, Hayam Ahmad Al-Sharawi and Noha Mohamed Osman
    Citation: Bulletin of the National Research Centre 2022 46:268
  3. World Wide Web and scientific literature record information regarding several organelles and mitochondria is not an exception. However, currently mitochondrial databases also provide information about non-mito...

    Authors: Deepak Yadav, Bharti Thakur, Deepak Kumar, Sheemona Chowdhary, Rajasri Bhattacharyya and Dibyajyoti Banerjee
    Citation: Bulletin of the National Research Centre 2022 46:266
  4. Cancer refers to a group of diseases characterized by the development of abnormal cells that divide uncontrollably and have the ability to infiltrate and destroy normal body tissue. Worldwide, it is the second...

    Authors: Anandakumar Pandi and Vanitha Manickam Kalappan
    Citation: Bulletin of the National Research Centre 2022 46:259
  5. Cytochrome P450 monooxygenases (CYPs) are exciting biocatalysts that catalyzes diverse regio- and stereoselective reactions of a broad range of substrates. The cytochrome P450 genes (CYPomes) of a chronically ...

    Authors: Lateef Babatunde Salam, Oluwafemi Sunday Obayori, Mathew Olusoji Ilori and Olukayode Oladipo Amund
    Citation: Bulletin of the National Research Centre 2022 46:256
  6. Breast cancer is the world's second leading cause of death in women. The problem of chemoresistance in breast cancer is proving to be a challenge for researchers and several oncologists all around the world. C...

    Authors: Dayanand Swami, Shafina Siddiqui, Urwashi Kumar, Shine Devarajan and Jyotirmoi Aich
    Citation: Bulletin of the National Research Centre 2022 46:249
  7. The continuous increase in the resistance of pathogenic bacteria to antimicrobial agents elicits a source of concern for public health. Developing a method that allows for swift evaluation of the antibiotic se...

    Authors: Olamide Joshua Babatunde, Ayomide Faith Okiti, Michael Tosin Bayode, Samson Oloruntola Babatunde and Ayo Mercy Olaniran
    Citation: Bulletin of the National Research Centre 2022 46:230
  8. Medicinal plants have been the mainstay for the treatment of various diseases since antiquity. The importance of ethnomedicinal plants in drug discovery and development can never be overemphasized. Breonadia sali...

    Authors: Uwaisu Iliyasu, Hajara Ibrahim, Umar Adamu Katsayal, Sani Ismaila Muhammad, Sani Shehu, William N. Setzer, Javad Sharifi-Rad and Ahmad Faizal Abdull Razis
    Citation: Bulletin of the National Research Centre 2022 46:227
  9. Pirin, a member of the cupin superfamily, is an iron-binding non-heme protein. It acts as a coregulator of several transcription factors, especially the members of NFκB transcription factor family. Based on th...

    Authors: Auroni Semonti Khan, Nahid Parvez, Tamim Ahsan, Sabrina Samad Shoily and Abu Ashfaqur Sajib
    Citation: Bulletin of the National Research Centre 2022 46:225
  10. Probiotics are beneficial microorganisms that alter microbial flora to promote human and animal health by ameliorating the physiological and psychological hitches and distress. The aim of the study was to inve...

    Authors: Jimoh Abdulazeez, Muhammad Zainab and Aliyu Muhammad
    Citation: Bulletin of the National Research Centre 2022 46:221
  11. The conservation of natural populations of plants is very important for maintaining biological diversity. Lycium barbarum (goji berries) is classified as a very rare plant in the Egyptian flora. Goji berry is a f...

    Authors: Manal El-salato Ala El-naby Ahmed
    Citation: Bulletin of the National Research Centre 2022 46:220
  12. Diabetes, a cardiometabolic condition with social and health ramifications, is already a global epidemic. Diabetes affects 422 million people worldwide, with the majority living in middle- and low-income count...

    Authors: Ezekiel A. Olugbogi, Damilola S. Bodun, Shola D. Omoseeye, Anita O. Onoriode, Favour O. Oluwamoroti, Joshua F. Adedara, Isaac A. Oriyomi, Fatimat O. Bello, Favour O. Olowoyeye, Oluwatomilola G. Laoye, Damilola B. Adebowale, Aanuoluwapo D. Adebisi and Olaposi I. Omotuyi
    Citation: Bulletin of the National Research Centre 2022 46:217
  13. Leptin exerts both protective and deleterious effects on the heart; the first occurs under hypoxia- or ischemia-associated damage, the second is a pro-hypertrophic factor on cardiomyocytes. Therefore, leptin c...

    Authors: Wendy Natalia Rosado Loman, Jarumi Hishel Cruz Hernández, Nancy Patricia Gómez-Crisóstomo, Erick N. de la Cruz-Hernández, Carlos Francisco Aguilar-Gamas and Eduardo Martínez-Abundis
    Citation: Bulletin of the National Research Centre 2022 46:213
  14. The current study was conducted to find out an eco-friendly and cost-efficient way to prepare copper nanoparticles (CuNPs) by utilizing Grewia asiatica L. leaf extract, which was found to be a very effective anti...

    Authors: Arifa Tahir, Cristina Quispe, Jesús Herrera-Bravo, Hafsa Iqbal, Zia ul Haq, Faiza Anum, Zeeshan Javed, Anam Sehar and Javad Sharifi-Rad
    Citation: Bulletin of the National Research Centre 2022 46:188
  15. Microorganisms' survival is based on the importance of growth factors found in the microbial environment, as well as their overwhelming appetite for survival which is controlled by their genetic material. This...

    Authors: Omololu Daniel Oladapo, Anthony Kayode Onifade and Michael Tosin Bayode
    Citation: Bulletin of the National Research Centre 2022 46:175
  16. The emerging viral pandemic worldwide is associated with a novel coronavirus, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). This virus is said to emerge from its epidemic center in Wuhan, China...

    Authors: Deepak Agarwal, Imran Zafar, Syed Umair Ahmad, Sujit Kumar, Qurat ul Ain, Jitendra Kumar Sundaray and Mohd Ashraf Rather
    Citation: Bulletin of the National Research Centre 2022 46:170
  17. The use of nitrile compounds is usually high, particularly in chemical industries, which calls for serious concern because of their relevance to the environment. The essential role of nitrilases in the bioreme...

    Authors: Adewale Kayode Ogunyemi, Olanike Maria Buraimoh, Bukola Caroline Ogunyemi, Titilola Aderonke Samuel, Matthew Olusoji Ilori and Olukayode Oladipo Amund
    Citation: Bulletin of the National Research Centre 2022 46:151
  18. In the present study, the medicinal plants were exclusively selected based on their significant anti-HIV and anticancer activities. The green synthesis of gold nanoparticles was carried out using the 15 medici...

    Authors: M. R. Kamala Priya and Priya R. Iyer
    Citation: Bulletin of the National Research Centre 2022 46:134
  19. Africa has a rich and diverse flora that people use for their food and health needs. This study aims to explore the possibility of using aqueous and/or ethanolic extracts of Alchornea cordifolia leaves as an alte...

    Authors: Ferdinand Adounkpe, Aimé Cézaire Ayena, Viridiane Aholoukpe, Victorien Dougnon, Jean-Robert Klotoe, Marc Medehouenou and Lamine Baba-Moussa
    Citation: Bulletin of the National Research Centre 2022 46:132
  20. Solanum khasianum is an important medicinal herb of the Solanaceae family. The present study was focused to determine the bioactive compounds in S. khasianum leaf and root extract by GC–MS analysis and their anti...

    Authors: Pavani Chirumamilla, Sunitha Bai Dharavath and Shasthree Taduri
    Citation: Bulletin of the National Research Centre 2022 46:127
  21. A common complication of any respiratory disease by a virus could be a secondary bacterial infection, which is known to cause an increase in severity. It is, however, not clear whether the presence of some opp...

    Authors: Olabisi Flora Davies-Bolorunduro, Muinah Adenike Fowora, Olufemi Samuel Amoo, Esther Adeniji, Kazeem Adewale Osuolale, Oluwatobi Oladele, Tochukwu Ifeanyi Onuigbo, Josephine Chioma Obi, Joy Oraegbu, Oluwatobi Ogundepo, Rahaman Ademolu Ahmed, Olagoke AbdulRazaq Usman, Bosede Ganiyat Iyapo, Adedamola Adejuwon Dada, Ngozi Onyia, Richard Adebayo Adegbola…
    Citation: Bulletin of the National Research Centre 2022 46:115
  22. Cancer is a significant public health problem worldwide and constitutes the second leading cause of death after cardiovascular disease. This study was thus designed to identify new natural compounds from Malag...

    Authors: Jean-Paul Koto-Te-Nyiwa Ngbolua, Jason T. Kilembe, Aristote Matondo, Colette Masengo Ashande, Janvier Mukiza, Célestin Mudogo Nzanzu, Fatiany Pierre Ruphin, Robijaona Baholy, Pius T. Mpiana and Virima Mudogo
    Citation: Bulletin of the National Research Centre 2022 46:101
  23. The world has been suffering from the COVID-19 pandemic (officially declared by WHO in March 2020), caused by the severe acute respiratory β-coronavirus 2 (SARS-CoV-2) since the last week of December 2019. The...

    Authors: Rashed Noor, Saadia Shareen and Muntasir Billah
    Citation: Bulletin of the National Research Centre 2022 46:96
  24. This study was carried out to investigate the antifungal activity of chitinase produced by Streptomyces species isolated from grassland soils against selected pathogenic fungi, namely: Magnaporthe oryzae, Fusariu...

    Authors: Fatuyi Olanipekun Ekundayo, Abisola Eniola Folorunsho, Tope Abraham Ibisanmi and Olayinka Bukola Olabanji
    Citation: Bulletin of the National Research Centre 2022 46:95
  25. Wild cocoyam (Caladium bicolar) is non-edible starchy material which is commonly known as ‘Ede umuagbara’ in the south-east region of Nigeria. Evaluating the potential of wild cocoyam for citric acid production w...

    Authors: Ifeanyi Boniface Ezeaa and Emmanuel Ezaka
    Citation: Bulletin of the National Research Centre 2022 46:84
  26. To mitigate the current COVID-19 pandemic by the severe acute respiratory coronavirus 2 (SARS-CoV-2), designing of repurposed antiviral drugs and the development of vaccines using different platforms have been...

    Authors: Rashed Noor
    Citation: Bulletin of the National Research Centre 2022 46:31
  27. During the second wave of the COVID-19 pandemic, an unusual increase in cases of mucormycosis was observed in India, owing to immunological dysregulation caused by the SARS-CoV-2 and the use of broad-spectrum ...

    Authors: Premnath Madanagopal, Nagarjun Ramprabhu and Rahul Jagadeesan
    Citation: Bulletin of the National Research Centre 2022 46:24
  28. The majority of pandemics are known to be a result of either bacteria or viruses out of which viruses seem to be an entity of growing concern due to the sheer number of yet unidentified and potentially threate...

    Authors: Priyanka Ray Choudhury, Tapoja Saha, Sachin Goel, Janvi Manish Shah and Deepak Ganjewala
    Citation: Bulletin of the National Research Centre 2022 46:18
  29. The emergence of antibiotic-resistant microorganisms has been largely associated with drug misuse, drug abuse, and indiscriminate disposal of drugs; however, the interactions between some environmental factors...

    Authors: Emmanuel Oluwaseun Garuba, Obinna Markraphael Ajunwa and Aishat Nana Ibrahim-King
    Citation: Bulletin of the National Research Centre 2021 45:216
  30. Actinidin is an anionic thiol-proteinase predominant and unique to Chinese gooseberry or kiwifruit, whose strong digestibility enables proteins or enzymes vulnerable to digestion. The arrangement of active cys...

    Authors: Vivek Kumar Dhiman, Vivek Chauhan, Shamsher Singh Kanwar, Devendra Singh and Himanshu Pandey
    Citation: Bulletin of the National Research Centre 2021 45:213
  31. The expression of apoptotic family of protein plays a major role in induction of programmed cell death. There are six major apoptotic proteins such as Caspase 12, Bcl 2, BAX, Cytochrome c, PARP3 and Mcl1. All ...

    Authors: M. R. Kamala Priya and Priya R. Iyer
    Citation: Bulletin of the National Research Centre 2021 45:212
  32. Indonesia has started the big project of COVID-19 vaccination program since 13 January 2021 by employing the first shot of vaccine to the President of Indonesia as the outbreak and rapid transmission of COVID-...

    Authors: Reviany V. Nidom, Setyarina Indrasari, Irine Normalina, Astria N. Nidom, Balqis Afifah, Lestari Dewi, Andra K. Putra, Arif N. M. Ansori, Muhammad K. J. Kusala, Mohammad Y. Alamudi and Chairul A. Nidom
    Citation: Bulletin of the National Research Centre 2021 45:200
  33. One of the parameters required for the assessment of food and feed safety is detection and identification of genetically modified organisms. Legislation in some countries necessitates detection and quantificat...

    Authors: Hanaa Abdel-Sadek Oraby, Nadia Aboul-Ftooh Aboul-Maaty and Hayam Ahmad Al-Sharawi
    Citation: Bulletin of the National Research Centre 2021 45:196
  34. The increase in multidrug resistance (MDR) among pathogenic bacteria responsible for infectious diseases has led to lack of effectiveness of some antibiotics. The ability of Escherichia coli to harbor resistant g...

    Authors: Martha Uzoaru Ajuga, Kome Otokunefor and Obakpororo Ejiro Agbagwa
    Citation: Bulletin of the National Research Centre 2021 45:173
  35. Data on the prevalence, genotypes and antibiotic resistance patterns of colonizing and infection-associated Staphylococcus aureus (S. aureus) strains both in humans and animals in Tanzania are scarce. Given the w...

    Authors: Tutu Mzee, Theckla Kazimoto, Joseph Madata, Rose Masalu, Markus Bischoff, Mecky Matee and Sören L. Becker
    Citation: Bulletin of the National Research Centre 2021 45:162
  36. Strategic crops need to be screened from time to time to select the most tolerant and stable genotypes incompatible with environmental conditions. This research experiments were carried out to screen thirteen ...

    Authors: Samy A. A. Heiba, Samira A. Osman, Sara E. I. Eldessouky, Atef A. A. Haiba and Rania T. Ali
    Citation: Bulletin of the National Research Centre 2021 45:151
  37. Among the physical evidence, bloodstain is one of the most common biological pieces of evidence at the crime scene, especially in violent crimes. Bloodstains are frequently seen at the crime scene and can be e...

    Authors: Tuğba Ünsal Sapan, Işıl Tuna Erdoğan and Sevil Atasoy
    Citation: Bulletin of the National Research Centre 2021 45:148
  38. A novel corona virus is formally named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which results in causing coronavirus disease 2019 (COVID-19). It is the latest prevalent pandemic worldwi...

    Authors: Sankari Mohan, M. Reshma Anjum, Anusha Kodidasu, T. V. N. Sai Prathyusha, Nunna Venkata Mrunalini and B. Kishori
    Citation: Bulletin of the National Research Centre 2021 45:139
  39. Gastroenteritis is a common infectious disease in children, which results in high mortality and morbidity, especially in resource-poor countries. This study presents the selected main gastroenteritis causing b...

    Authors: Mohammad Sharif Uddin, Md. Mijanur Rahman, Md. Omar Faruk, Asma Talukder, Md. Imranul Hoq, Suman Das and K. M. Shariful Islam
    Citation: Bulletin of the National Research Centre 2021 45:138
  40. The matter of antimicrobial resistance evokes the urgency to explore alternatives to the antibiotics traditionally used for microbial infections. This study aimed to elucidate the mechanism of action of the an...

    Authors: Victorien Dougnon, Edna Hounsa, Hornel Koudokpon, Eric Agbodjento, Anny Afaton, Kevin Sintondji, Jean Robert Klotoe, Julien Segbo and Lamine Baba-Moussa
    Citation: Bulletin of the National Research Centre 2021 45:107
  41. Endophytes are highly beneficial species of microbes that live in symbiosis with plant tissues in the setting. Endophytes are difficult to isolate in their natural environment, and they are understudied despit...

    Authors: Chijioke E. Ezeobiora, Nwamaka H. Igbokwe, Dina H. Amin and Udoma E. Mendie
    Citation: Bulletin of the National Research Centre 2021 45:103
  42. Malaria is one of the tropical diseases of universal concern particularly with continuous appearance of resistant strains of P.falciparum. This calls for continous screening of traditional plants such that new an...

    Authors: Uchechi E. Enenebeaku, Nnamdi C. Ukwandu, Ifeyinwa C. Mgbemena, Harriet C. Nwigwe, Conrad K. Enenebeaku, Chidi E. Duru and Odangowei I. Ogidi
    Citation: Bulletin of the National Research Centre 2021 45:75
  43. Rice forms a significant portion of food consumed in most household worldwide. Rice production has been hampered by soil factors such as ferruginousity which has limited phosphorus availability; an important m...

    Authors: Musa Saheed Ibrahim and Beckley Ikhajiagbe
    Citation: Bulletin of the National Research Centre 2021 45:70
  44. The growing number of cases, severity and fatality of the COVID-19 pandemic, coupled with the fact that no cure has been found has made infected individuals especially in Africa, to resort to the consumption o...

    Authors: Chidi Edbert Duru, Ijeoma Akunna Duru and Abayomi Emmanuel Adegboyega
    Citation: Bulletin of the National Research Centre 2021 45:57