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Bulletin of the National Research Centre
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Molecular Biology and Biotechnology

  1. The current study was conducted to find out an eco-friendly and cost-efficient way to prepare copper nanoparticles (CuNPs) by utilizing Grewia asiatica L. leaf extract, which was found to be a very effective anti...

    Authors: Arifa Tahir, Cristina Quispe, Jesús Herrera-Bravo, Hafsa Iqbal, Zia ul Haq, Faiza Anum, Zeeshan Javed, Anam Sehar and Javad Sharifi-Rad
    Citation: Bulletin of the National Research Centre 2022 46:188
    Content type: Research Published on:

  2. Microorganisms' survival is based on the importance of growth factors found in the microbial environment, as well as their overwhelming appetite for survival which is controlled by their genetic material. This...

    Authors: Omololu Daniel Oladapo, Anthony Kayode Onifade and Michael Tosin Bayode
    Citation: Bulletin of the National Research Centre 2022 46:175
    Content type: Research Published on:

  3. The emerging viral pandemic worldwide is associated with a novel coronavirus, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). This virus is said to emerge from its epidemic center in Wuhan, China...

    Authors: Deepak Agarwal, Imran Zafar, Syed Umair Ahmad, Sujit Kumar, Qurat ul Ain, Jitendra Kumar Sundaray and Mohd Ashraf Rather
    Citation: Bulletin of the National Research Centre 2022 46:170
    Content type: Review Published on:

  4. The use of nitrile compounds is usually high, particularly in chemical industries, which calls for serious concern because of their relevance to the environment. The essential role of nitrilases in the bioreme...

    Authors: Adewale Kayode Ogunyemi, Olanike Maria Buraimoh, Bukola Caroline Ogunyemi, Titilola Aderonke Samuel, Matthew Olusoji Ilori and Olukayode Oladipo Amund
    Citation: Bulletin of the National Research Centre 2022 46:151
    Content type: Research Published on:

  5. In the present study, the medicinal plants were exclusively selected based on their significant anti-HIV and anticancer activities. The green synthesis of gold nanoparticles was carried out using the 15 medici...

    Authors: M. R. Kamala Priya and Priya R. Iyer
    Citation: Bulletin of the National Research Centre 2022 46:134
    Content type: Research Published on:

  6. Africa has a rich and diverse flora that people use for their food and health needs. This study aims to explore the possibility of using aqueous and/or ethanolic extracts of Alchornea cordifolia leaves as an alte...

    Authors: Ferdinand Adounkpe, Aimé Cézaire Ayena, Viridiane Aholoukpe, Victorien Dougnon, Jean-Robert Klotoe, Marc Medehouenou and Lamine Baba-Moussa
    Citation: Bulletin of the National Research Centre 2022 46:132
    Content type: Research Published on:

  7. Solanum khasianum is an important medicinal herb of the Solanaceae family. The present study was focused to determine the bioactive compounds in S. khasianum leaf and root extract by GC–MS analysis and their anti...

    Authors: Pavani Chirumamilla, Sunitha Bai Dharavath and Shasthree Taduri
    Citation: Bulletin of the National Research Centre 2022 46:127
    Content type: Research Published on:

  8. A common complication of any respiratory disease by a virus could be a secondary bacterial infection, which is known to cause an increase in severity. It is, however, not clear whether the presence of some opp...

    Authors: Olabisi Flora Davies-Bolorunduro, Muinah Adenike Fowora, Olufemi Samuel Amoo, Esther Adeniji, Kazeem Adewale Osuolale, Oluwatobi Oladele, Tochukwu Ifeanyi Onuigbo, Josephine Chioma Obi, Joy Oraegbu, Oluwatobi Ogundepo, Rahaman Ademolu Ahmed, Olagoke AbdulRazaq Usman, Bosede Ganiyat Iyapo, Adedamola Adejuwon Dada, Ngozi Onyia, Richard Adebayo Adegbola…
    Citation: Bulletin of the National Research Centre 2022 46:115
    Content type: Research Published on:

  9. Cancer is a significant public health problem worldwide and constitutes the second leading cause of death after cardiovascular disease. This study was thus designed to identify new natural compounds from Malag...

    Authors: Jean-Paul Koto-Te-Nyiwa Ngbolua, Jason T. Kilembe, Aristote Matondo, Colette Masengo Ashande, Janvier Mukiza, Célestin Mudogo Nzanzu, Fatiany Pierre Ruphin, Robijaona Baholy, Pius T. Mpiana and Virima Mudogo
    Citation: Bulletin of the National Research Centre 2022 46:101
    Content type: Research Published on:

  10. The world has been suffering from the COVID-19 pandemic (officially declared by WHO in March 2020), caused by the severe acute respiratory β-coronavirus 2 (SARS-CoV-2) since the last week of December 2019. The...

    Authors: Rashed Noor, Saadia Shareen and Muntasir Billah
    Citation: Bulletin of the National Research Centre 2022 46:96
    Content type: Review Published on:

  11. This study was carried out to investigate the antifungal activity of chitinase produced by Streptomyces species isolated from grassland soils against selected pathogenic fungi, namely: Magnaporthe oryzae, Fusariu...

    Authors: Fatuyi Olanipekun Ekundayo, Abisola Eniola Folorunsho, Tope Abraham Ibisanmi and Olayinka Bukola Olabanji
    Citation: Bulletin of the National Research Centre 2022 46:95
    Content type: Research Published on:

  12. Wild cocoyam (Caladium bicolar) is non-edible starchy material which is commonly known as ‘Ede umuagbara’ in the south-east region of Nigeria. Evaluating the potential of wild cocoyam for citric acid production w...

    Authors: Ifeanyi Boniface Ezeaa and Emmanuel Ezaka
    Citation: Bulletin of the National Research Centre 2022 46:84
    Content type: Research Published on:

  15. To mitigate the current COVID-19 pandemic by the severe acute respiratory coronavirus 2 (SARS-CoV-2), designing of repurposed antiviral drugs and the development of vaccines using different platforms have been...

    Authors: Rashed Noor
    Citation: Bulletin of the National Research Centre 2022 46:31
    Content type: Review Published on:

  16. During the second wave of the COVID-19 pandemic, an unusual increase in cases of mucormycosis was observed in India, owing to immunological dysregulation caused by the SARS-CoV-2 and the use of broad-spectrum ...

    Authors: Premnath Madanagopal, Nagarjun Ramprabhu and Rahul Jagadeesan
    Citation: Bulletin of the National Research Centre 2022 46:24
    Content type: Research Published on:

  17. The majority of pandemics are known to be a result of either bacteria or viruses out of which viruses seem to be an entity of growing concern due to the sheer number of yet unidentified and potentially threate...

    Authors: Priyanka Ray Choudhury, Tapoja Saha, Sachin Goel, Janvi Manish Shah and Deepak Ganjewala
    Citation: Bulletin of the National Research Centre 2022 46:18
    Content type: Review Published on:

  19. The emergence of antibiotic-resistant microorganisms has been largely associated with drug misuse, drug abuse, and indiscriminate disposal of drugs; however, the interactions between some environmental factors...

    Authors: Emmanuel Oluwaseun Garuba, Obinna Markraphael Ajunwa and Aishat Nana Ibrahim-King
    Citation: Bulletin of the National Research Centre 2021 45:216
    Content type: Research Published on:

  20. Actinidin is an anionic thiol-proteinase predominant and unique to Chinese gooseberry or kiwifruit, whose strong digestibility enables proteins or enzymes vulnerable to digestion. The arrangement of active cys...

    Authors: Vivek Kumar Dhiman, Vivek Chauhan, Shamsher Singh Kanwar, Devendra Singh and Himanshu Pandey
    Citation: Bulletin of the National Research Centre 2021 45:213
    Content type: Research Published on:

  21. The expression of apoptotic family of protein plays a major role in induction of programmed cell death. There are six major apoptotic proteins such as Caspase 12, Bcl 2, BAX, Cytochrome c, PARP3 and Mcl1. All ...

    Authors: M. R. Kamala Priya and Priya R. Iyer
    Citation: Bulletin of the National Research Centre 2021 45:212
    Content type: Research Published on:

  22. Indonesia has started the big project of COVID-19 vaccination program since 13 January 2021 by employing the first shot of vaccine to the President of Indonesia as the outbreak and rapid transmission of COVID-...

    Authors: Reviany V. Nidom, Setyarina Indrasari, Irine Normalina, Astria N. Nidom, Balqis Afifah, Lestari Dewi, Andra K. Putra, Arif N. M. Ansori, Muhammad K. J. Kusala, Mohammad Y. Alamudi and Chairul A. Nidom
    Citation: Bulletin of the National Research Centre 2021 45:200
    Content type: Research Published on:

  23. One of the parameters required for the assessment of food and feed safety is detection and identification of genetically modified organisms. Legislation in some countries necessitates detection and quantificat...

    Authors: Hanaa Abdel-Sadek Oraby, Nadia Aboul-Ftooh Aboul-Maaty and Hayam Ahmad Al-Sharawi
    Citation: Bulletin of the National Research Centre 2021 45:196
    Content type: Research Published on:

  25. The increase in multidrug resistance (MDR) among pathogenic bacteria responsible for infectious diseases has led to lack of effectiveness of some antibiotics. The ability of Escherichia coli to harbor resistant g...

    Authors: Martha Uzoaru Ajuga, Kome Otokunefor and Obakpororo Ejiro Agbagwa
    Citation: Bulletin of the National Research Centre 2021 45:173
    Content type: Research Published on:

  26. Data on the prevalence, genotypes and antibiotic resistance patterns of colonizing and infection-associated Staphylococcus aureus (S. aureus) strains both in humans and animals in Tanzania are scarce. Given the w...

    Authors: Tutu Mzee, Theckla Kazimoto, Joseph Madata, Rose Masalu, Markus Bischoff, Mecky Matee and Sören L. Becker
    Citation: Bulletin of the National Research Centre 2021 45:162
    Content type: Review Published on:

  28. Strategic crops need to be screened from time to time to select the most tolerant and stable genotypes incompatible with environmental conditions. This research experiments were carried out to screen thirteen ...

    Authors: Samy A. A. Heiba, Samira A. Osman, Sara E. I. Eldessouky, Atef A. A. Haiba and Rania T. Ali
    Citation: Bulletin of the National Research Centre 2021 45:151
    Content type: Research Published on:

  29. Among the physical evidence, bloodstain is one of the most common biological pieces of evidence at the crime scene, especially in violent crimes. Bloodstains are frequently seen at the crime scene and can be e...

    Authors: Tuğba Ünsal Sapan, Işıl Tuna Erdoğan and Sevil Atasoy
    Citation: Bulletin of the National Research Centre 2021 45:148
    Content type: Research Published on:

  30. A novel corona virus is formally named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which results in causing coronavirus disease 2019 (COVID-19). It is the latest prevalent pandemic worldwi...

    Authors: Sankari Mohan, M. Reshma Anjum, Anusha Kodidasu, T. V. N. Sai Prathyusha, Nunna Venkata Mrunalini and B. Kishori
    Citation: Bulletin of the National Research Centre 2021 45:139
    Content type: Review Published on:

  31. Gastroenteritis is a common infectious disease in children, which results in high mortality and morbidity, especially in resource-poor countries. This study presents the selected main gastroenteritis causing b...

    Authors: Mohammad Sharif Uddin, Md. Mijanur Rahman, Md. Omar Faruk, Asma Talukder, Md. Imranul Hoq, Suman Das and K. M. Shariful Islam
    Citation: Bulletin of the National Research Centre 2021 45:138
    Content type: Research Published on:

  32. The matter of antimicrobial resistance evokes the urgency to explore alternatives to the antibiotics traditionally used for microbial infections. This study aimed to elucidate the mechanism of action of the an...

    Authors: Victorien Dougnon, Edna Hounsa, Hornel Koudokpon, Eric Agbodjento, Anny Afaton, Kevin Sintondji, Jean Robert Klotoe, Julien Segbo and Lamine Baba-Moussa
    Citation: Bulletin of the National Research Centre 2021 45:107
    Content type: Research Published on:

  33. Endophytes are highly beneficial species of microbes that live in symbiosis with plant tissues in the setting. Endophytes are difficult to isolate in their natural environment, and they are understudied despit...

    Authors: Chijioke E. Ezeobiora, Nwamaka H. Igbokwe, Dina H. Amin and Udoma E. Mendie
    Citation: Bulletin of the National Research Centre 2021 45:103
    Content type: Review Published on:

  34. Malaria is one of the tropical diseases of universal concern particularly with continuous appearance of resistant strains of P.falciparum. This calls for continous screening of traditional plants such that new an...

    Authors: Uchechi E. Enenebeaku, Nnamdi C. Ukwandu, Ifeyinwa C. Mgbemena, Harriet C. Nwigwe, Conrad K. Enenebeaku, Chidi E. Duru and Odangowei I. Ogidi
    Citation: Bulletin of the National Research Centre 2021 45:75
    Content type: Research Published on:

  35. Rice forms a significant portion of food consumed in most household worldwide. Rice production has been hampered by soil factors such as ferruginousity which has limited phosphorus availability; an important m...

    Authors: Musa Saheed Ibrahim and Beckley Ikhajiagbe
    Citation: Bulletin of the National Research Centre 2021 45:70
    Content type: Research Published on:

  36. The growing number of cases, severity and fatality of the COVID-19 pandemic, coupled with the fact that no cure has been found has made infected individuals especially in Africa, to resort to the consumption o...

    Authors: Chidi Edbert Duru, Ijeoma Akunna Duru and Abayomi Emmanuel Adegboyega
    Citation: Bulletin of the National Research Centre 2021 45:57
    Content type: Research Published on:

  38. The identification of banana cultivars genome is needed to provide a valid identity from the accession of bananas which are used as basic data in the management of in situ and ex situ banana conservation as we...

    Authors: Rasyadan T. Probojati, Dwi Listyorini, Sulisetijono Sulisetijono and Didik Wahyudi
    Citation: Bulletin of the National Research Centre 2021 45:33
    Content type: Research Published on:

  40. This study was aimed to determine the prevalence of qnr genes among fluoroquinolone-resistant Escherichia coli (FREC) isolates from Nigeria. Antimicrobial susceptibility testing was performed by disc diffusion te...

    Authors: Chibuzor M. Nsofor, Mirabeau Y. Tattfeng and Chijioke A. Nsofor
    Citation: Bulletin of the National Research Centre 2021 45:26
    Content type: Research Published on:

  41. Banana bunchy top virus (BBTV) is a destructive viral disease in many countries including Egypt; it causes severe economic losses in banana crop. Recently, nanotechnology was used to generate resistance against p...

    Authors: Heba A. Mahfouze, Noha K. El-Dougdoug and Sherin A. Mahfouze
    Citation: Bulletin of the National Research Centre 2020 44:199
    Content type: Research Published on:

  42. COVID-19, a pandemic declared by WHO, has infected about 39.5 million and killed about 1.1 million people throughout the world. There is the urgent need of more studies to identify the novel drug targets and t...

    Authors: Rahul Kunwar Singh, Brijesh Singh Yadav and Tribhuvan Mohan Mohapatra
    Citation: Bulletin of the National Research Centre 2020 44:193
    Content type: Review Published on:

  43. The role of mouse mammary tumor-like virus (MMTV-like virus) in human breast cancer (BC) has already been widely investigated worldwide with conflicting results. Although the researchers tried to establish the...

    Authors: Yasir Hameed, Muhammad Usman and Mukhtiar Ahmad
    Citation: Bulletin of the National Research Centre 2020 44:183
    Content type: Research Published on:

  44. α-Galactosidase is widely used in various biotechnological applications such as food processing, beet sugar, the pulp and paper industries, synthesis of oligosaccharides by trans-galactosylation, hydraulic fra...

    Authors: Naganagouda Kote, A. C. Manjula, T. Vishwanatha and Aravind Gouda G. Patil
    Citation: Bulletin of the National Research Centre 2020 44:168
    Content type: Research Published on:

  45. The K1, K2, and K28 toxins are usually encoded by several cytoplasmically genetic satellite dsRNAs (M1, M2, and M28), which are encapsulated with virus-like particles (VLPs) and reliant on an additional assemb...

    Authors: Najwa Mohammed Jameel Ali Abu-Mejdad, Adnan I. Al-Badran, Abdullah H. Al-Saadoon and Mohammed Hussein Minati
    Citation: Bulletin of the National Research Centre 2020 44:162
    Content type: Research Published on:

  46. This study was conducted to estimate the antifungal activity and efficiency of purified killer toxins (TK and WK) produced by Torulaspora delbrueckii and Wickerhamomyces anomalus as alternative drugs of resistant...

    Authors: Najwa Mohammed Jameel Ali Abu-Mejdad, Abdullah H. Al-Saadoon, Adnan I. Al-Badran and Mohammed Hussein Minati
    Citation: Bulletin of the National Research Centre 2020 44:148
    Content type: Research Published on:

  47. The present study evaluated levels of polymerization of deoxygenated sickle hemoglobin molecules (poly-dHbS-M) in the presence of fractionated leaf extracts of Anacardium occidentale Linn., Psidium guajava Linn.,...

    Authors: Paul C. Chikezie, Raphael C. Ekeanyanwu and Adaeze B. Chile-Agada
    Citation: Bulletin of the National Research Centre 2020 44:135
    Content type: Research Published on:

  48. The reoccurrence of the resistant strains of Mycobacterium tuberculosis to available drugs/medications has mandated for the development of more effective anti-tubercular agents with efficient activities. Therefor...

    Authors: Shola Elijah Adeniji, David Ebuka Arthur, Mustapha Abdullahi and Olajumoke Bosede Adalumo
    Citation: Bulletin of the National Research Centre 2020 44:132
    Content type: Research Published on:

  49. α-Amylase randomly hydrolyzes starch molecule to produce oligosaccharides of different chain length. It is among the most significant hydrolytic enzymes used in industrial applications. Enzyme immobilization i...

    Authors: Mohamed A. A. Abdella, Gamal M. El-Sherbiny, Aliaa R. El-Shamy, Sherien M. M. Atalla and Samia A. Ahmed
    Citation: Bulletin of the National Research Centre 2020 44:40
    Content type: Research Published on:

  50. Maize is one of the important cereal food crops in the world. High temperature stress causes adverse influence on plant growth. When plants are exposed to high temperatures, they produce heat shock proteins (H...

    Authors: Mahmoud Hussien Abou-Deif, Mohamed Abdel-Salam Rashed, Kamal Mohamed Khalil and Fatma El-Sayed Mahmoud
    Citation: Bulletin of the National Research Centre 2019 43:199
    Content type: Research Published on: