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Bulletin of the National Research Centre
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Medicine and Human Genetics

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  1. Multiple myeloma (MM) is characterized by infiltration of neoplastic plasma cells in the bone marrow. Although many novel agents have been developed in the last decade, MM remains a non-curable disease. The as...

    Authors: Esma Evrim Dogan, Aysenur Arslan, Naciye Demirel, Demet Aydin, Ilknur Mansuroglu, Suheyla Atak, Fatma Keklik Karadag, Rafet Eren and Guray Saydam
    Citation: Bulletin of the National Research Centre 2022 46:242
    Content type: Research Published on:

  2. Several studies have investigated sleep disorders in the general population. However, a few studies were conducted among the working population and none among the Egyptian workers. We aimed to assess the preva...

    Authors: Ehab Salah Eshak
    Citation: Bulletin of the National Research Centre 2022 46:240
    Content type: Research Published on:

  3. The production of a good quality chest radiograph depends on the selection of appropriate kilovoltage and current–time product while keeping the radiation dose to patients as low as possible. This study assess...

    Authors: Emmanuel O. Esien-umo, Ndubuisi O. Chiaghanam, Akwa E. Erim, Michael Effa and Nneoyi O. Egbe
    Citation: Bulletin of the National Research Centre 2022 46:229
    Content type: Research Published on:

  5. Distinguishing between a pituitary adenoma and a pituicytoma can be challenging. Hormonal changes in pituicytomas are uncommon, and the tumor's mass effect has triggered most symptoms. There were only two repo...

    Authors: Magdelene Amoateng, Eiman Ibrahim, Yasir Ahmad, Anoush Calikyan and Ilja Hulinsky
    Citation: Bulletin of the National Research Centre 2022 46:218
    Content type: Case Report Published on:

  6. The increase in the demand for synthetic drugs due to the surge in the cases of drug-resistant infectious organisms has led to the search for new medicines in plants. Some plants have phytochemicals that can serv...

    Authors: O. M. Oyawoye, T. M. Olotu, S. C. Nzekwe, J. A. Idowu, T. A. Abdullahi, S. O. Babatunde, I. A. Ridwan, Gaber E. Batiha, Nike Idowu, Mohammed Alorabi and Hani Faidah
    Citation: Bulletin of the National Research Centre 2022 46:214
    Content type: Research Published on:

  7. The development of barotrauma in COVID-19 patients who were ventilated and admitted to the intensive treatment unit seemed to have been a problematic issue in the COVID era. This study aimed to explore the pos...

    Authors: Roopak Dubey, Kamal Kumar Sen and Aparajita Mishra
    Citation: Bulletin of the National Research Centre 2022 46:212
    Content type: Research Published on:

  8. Abnormal thyroid hormone levels have been reported in type 2, but the relationship between thyroid hormone levels and glycaemic indices: fasting plasma glucose (FPG), C-peptide (C-pep) and glycated haemoglobin...

    Authors: Idongesit Kokoabasi Isong, Christopher E. J. Udiong and Uwem Okon Akpan
    Citation: Bulletin of the National Research Centre 2022 46:211
    Content type: Research Published on:

  9. This study aimed to evaluate the relationship between cardiac troponin I and T (cTnI, cTnT) and creatine kinase (CK)-MB during the acute phase of Kawasaki disease (KD) and the development of coronary artery in...

    Authors: Mahdieh Mousavi Torshizi, Seyed-Reza Raeeskarami, Fatemeh Tahghighi, Elaheh Malakan-Rad, Mohammad-Hassan Moradinejad, Yahya Aghighi and Vahid Ziaee
    Citation: Bulletin of the National Research Centre 2022 46:203
    Content type: Research Published on:

  10. Alcohol intake, particularly to cope up with stress and depression experienced by commercial drivers during the peak of the COVID-19 pandemic, is alarming as a rise in sales has been reported in certain countr...

    Authors: Great Iruoghene Edo and Laurine Chikodiri Nwosu
    Citation: Bulletin of the National Research Centre 2022 46:197
    Content type: Research Published on:

  11. On the staggering emergence of the Omicron variant, numerous questions arose about the evolution of virulence and transmissibility in microbes.

    Authors: Antoine AbdelMassih, Abrar Sedky, Ahmed Shalaby, AlAmira-Fawzia Shalaby, Alia Yasser, Aya Mohyeldin, Basma Amin, Basma Saleheen, Dina Osman, Elaria Samuel, Emmy Abdelfatah, Eveen Albustami, Farida ElGhamry, Habiba Khaled, Hana Amr, Hanya Gaber…
    Citation: Bulletin of the National Research Centre 2022 46:194
    Content type: Review Published on:

  12. A variety of accessible data, including those of single-nucleotide polymorphisms (SNPs) on the human p53 gene, are made widely available on a global scale. Owing to this, our investigation aimed to deal with t...

    Authors: Saruar Alam, Mohammad Sayem, Martiniano Bello, Sadia Islam Mou, Nairita Ahsan Faruqui, Faruk Hossain and Md. Kamrul Hasan
    Citation: Bulletin of the National Research Centre 2022 46:191
    Content type: Research Published on:

  13. Early detection of delirium through systematic screening is essential to mitigate and prevent possible consequences. The 4 'A's Test (4AT) is a new tool that can be used for delirium detection easily and witho...

    Authors: Olga Muser, Kevin Seiler, Stefanie Bachnick, Beatrice Gehri, Franziska Zúñiga and Wolfgang Hasemann
    Citation: Bulletin of the National Research Centre 2022 46:179
    Content type: Research Published on:

  14. Bryonia alba extract is a well-known drug which is being utilized as phytomedicines and homoeopathic preparations since more than two centuries. This medicine is frequently used in clinical practice for flu-like ...

    Authors: Pritam Goswami, Debasmita Chatterjee, Sayak Ghosh, Krishnendu Paira and Satadal Das
    Citation: Bulletin of the National Research Centre 2022 46:169
    Content type: Research Published on:

  15. Nonalcoholic fatty liver disease (NAFLD) is a silent disease with increasing prevalence. High levels of serum uric acid (SUA) have been associated with cardiometabolic diseases, yet the possible association be...

    Authors: Mariana F. Leite, Ariele B. Haagsma, Paulo-André B. Machado-Júnior, Grasiele L. Martins, Márcia Olandoski and Cristina P. Baena
    Citation: Bulletin of the National Research Centre 2022 46:168
    Content type: Research Published on:

  16. Nutritional care in patients with a severe head injury is of utmost importance, as nutritional deficiency can affect the outcomes in these patients. The purpose of this study was to assess the feasibility, and...

    Authors: Dharmesh Balsarkar, Hussain Shaikh, Sachin Suryawanshi, Munaafroz Shaikh, Ajay Alva and Ravi Warat
    Citation: Bulletin of the National Research Centre 2022 46:161
    Content type: Research Published on:

  17. Immunocompromised individuals are expected to be more prone to severe diseases and, subsequently, death. Genetic disorders and polymorphisms in genes involved in the immune system, such as human leukocyte anti...

    Authors: Narges Ansari, Mina Jahangiri, Kimia Shirbandi, Mina Ebrahimi and Fakher Rahim
    Citation: Bulletin of the National Research Centre 2022 46:158
    Content type: Research Published on:

  18. COVID-19 is a pandemic that ravaged the world in manners that were never seen in the recent past, and one of the measures to stem the tide of this ravaging pandemic is a stay-at-home order referred to as lockd...

    Authors: Patrick Ayi Ewah, Adetoyeje Y Oyeyemi, Adewale L Oyeyemi, Saturday N Oghumu, Peter Agba Awhen, Mary Ogaga and Lucy Inyang Edet
    Citation: Bulletin of the National Research Centre 2022 46:155
    Content type: Research Published on:

  19. Necrotizing fasciitis is an aggressive infection of the soft tissues and subcutaneous fascia. The involvement of the head and neck region is very rare but carries significant mortality. Negative pressure wound...

    Authors: Kasim S. Kasim Aljanabi, Talib almaqbali and Arfath Mustafa
    Citation: Bulletin of the National Research Centre 2022 46:154
    Content type: Case Report Published on:

  21. Recurrent malaria infection is a major phenomenon in a hightransmission zone with deplorable health and socioeconomic consequences on individuals and the public. However, the association between parasitaemia, ...

    Authors: Abdulkareem Olarewaju Babamale, Adam Olaitan Abdulkareem, Oyewole Jamiu Yinka, Kolawole Folasade, Babawale Oluwapelumi Olatundun, Onitayo Faith Ayodipo, Mohammad Mosleh Uddin and Uade Samuel Ugbomoiko
    Citation: Bulletin of the National Research Centre 2022 46:147
    Content type: Research Published on:

  22. The changing epidemiological profile of the COVID-19 pandemic and the uncertain clinical picture of patients characterise this ongoing and most challenging health event.

    Authors: Zayid K. Almayahi, A. V. Raveendran, Rashid Al Malki, Amira Safwat, Muradjan Al Baloshi, Amal Abbas, Ahmed S. Al Salami, Sami M. Al Mujaini, Khalid Al Dhuhli and Said Al Mandhari
    Citation: Bulletin of the National Research Centre 2022 46:139
    Content type: Research Published on:

  23. The tumor growth pattern in breast cancer appears to be variable and unpredictable. A minor increase in size in a pre-existing lesion, especially under 1 cm, corresponds to a more pronounced increase in volume.

    Authors: Seda Aladag Kurt and Varol Celik
    Citation: Bulletin of the National Research Centre 2022 46:136
    Content type: Case Report Published on:

  24. Hamartoma refers to the excessive focal growth of cells and tissues in organs, which is between malformation and benign tumor. Hamartomas are commonly seen in the lung, but rare in the retroperitoneum.

    Authors: Lesheng Huang, Tianzhu Liu, Se Peng, Hui Peng, Jun Chen, Jinghua Jiang, Wanchun Zhang, Huijia Tang and Hongyi Li
    Citation: Bulletin of the National Research Centre 2022 46:129
    Content type: Case Report Published on:

  25. High body mass index constitutes a risk for nephrolithiasis in the context of metabolic syndrome. The majority of these renal stones are either composed of Urate or Calcium Oxalate. We aimed to evaluate the ra...

    Authors: Nermine N. Mahfouz, Azza Abd El-Shaheed, Reham F. Fahmy, Sara F. Sallam, Salwa Refat El-Zayat, Hiba Sibaii, Mahitab I. EL-Kassaby and Hagar H. Mourad
    Citation: Bulletin of the National Research Centre 2022 46:125
    Content type: Research Published on:

  27. Acute myocardial infraction (AMI) is a leading cause of morbidity. As anti-diabetic drugs affect the cardiovascular risk of diabetic patients independent of their glucose lowering effect, this study was aimed ...

    Authors: Mostafa Mahmoud Ibrahim, Mohamed Mostafa Khedr, Manal Hamza Morsy, Noha Mohamed Badae and Soha Elatrebi
    Citation: Bulletin of the National Research Centre 2022 46:123
    Content type: Research Published on:

  28. The use of medicinal plants in curing diseases is an ancient culture still in use in many parts of the world. Many plants have been proven to have precise ethno-pharmacological relevance. On the contrary, many...

    Authors: Arpita Bardoloi and Amar Deep Soren
    Citation: Bulletin of the National Research Centre 2022 46:119
    Content type: Review Published on:

  29. Successful response to treatment of HIV infection is largely determined by adherence to antiretroviral therapy (ART) and manifests as an improvement in CD4 counts. Certain challenges to attaining high rates of...

    Authors: Kiran Rajput, Joanna Mary Roy, Suhas Chaudhari and Vishal Dnyaneshwar Sawant
    Citation: Bulletin of the National Research Centre 2022 46:118
    Content type: Research Published on:

  30. Injection for vaccinations is the most prevalent source of iatrogenic pain in infants. The facilitated rocking movement is a new technique which is to be evaluated to reduce vaccination-induced pain in newborn...

    Authors: Jayesh P. Yadav, Alka Agrawal and Vishal Dnyaneshwar Sawant
    Citation: Bulletin of the National Research Centre 2022 46:117
    Content type: Research Published on:

  31. Vasculitis and phlebitis with vascular occlusion within appendix specimen is rare. Several authors have reported COVID-19 related veno-occlusive disease in hepatic pathology, but lymphoid aggregation with phle...

    Authors: Abdus Salam Raju, Aditya Thomas Benjamin, Tristan Rutland, Luke Liu and Paul Lambrakis
    Citation: Bulletin of the National Research Centre 2022 46:114
    Content type: Case Report Published on:

    The Correction to this article has been published in Bulletin of the National Research Centre 2022 46:137

  32. Microscopic abnormalities are common findings on routine urinalysis performed for various clinical reasons. As a small proportion of these may indicate an underlying malignancy, a large number of patients with...

    Authors: Zulfadhly Murtadha Afiq Zainal Bahren
    Citation: Bulletin of the National Research Centre 2022 46:104
    Content type: Research Published on:

  33. Viral pneumonias are a major cause of childhood mortality. Proper management needs early and accurate diagnosis. This study objective is to investigate the viral etiologies of pneumonia in children.

    Authors: Amira S. El Refay, Manal A. Shehata, Lobna S. Sherif, Hala G. El Nady, Naglaa Kholoussi, Shams Kholoussi, Nevine R. El Baroudy, Mokhtar R. Gomma, Sara H. Mahmoud, Noura M. Abo Shama, Ola Bagato, Ahmed El Taweel, Ahmed kandeil and Mohamed A. Ali
    Citation: Bulletin of the National Research Centre 2022 46:103
    Content type: Research Published on:

  34. The hyperinflammatory state leading to an aberrant cytokine production, culminating in acute respiratory distress syndrome, sepsis and multi-organ dysfunction contribute much to the pathophysiologies of severe...

    Authors: Rahul Gupta
    Citation: Bulletin of the National Research Centre 2022 46:100
    Content type: Letter to the Editor Published on:

  35. Faecal incontinence is a common anorectal medical trouble among adult population. The aim was to compare the efficacy of biofeedback pelvic floor muscle training versus posterior tibial nerve electrical stimul...

    Authors: Mervat Sheta Elsawy and Emmanuel Kamal Aziz Saba
    Citation: Bulletin of the National Research Centre 2022 46:99
    Content type: Research Published on:

  38. The long-acting reversible contraceptive method is one way to overcome the high population growth rate. The long-term contraception method is more efficient to regulate pregnancy because it can be used for a l...

    Authors: Fitriana Putri Utami, Erni Gustina, Dedik Sulistiawan, Ratu Matahari and Bakti Permata Sari
    Citation: Bulletin of the National Research Centre 2022 46:89
    Content type: Research Published on:

  40. Ochronotic arthropathy affecting the hip and knee joints is one of the musculoskeletal manifestations of alkaptonuria which results from a tyrosine amino acid metabolism disorder. The condition has no definiti...

    Authors: Ahmed A. Khalifa, Mohamed M. A. Moustafa, Hatem Bakr and Ahmed M. Abdelaal
    Citation: Bulletin of the National Research Centre 2022 46:76
    Content type: Case Report Published on:

  41. Hormone production by the thyroid gland is a prime aspect of maintaining body homeostasis. In this study, the ability of single artificial intelligence (AI)-based models, namely multi-layer perceptron (MLP), s...

    Authors: Abdullahi Garba Usman, Umar Muhammad Ghali, Mohamed Alhosen Ali Degm, Salisu M. Muhammad, Evren Hincal, Abdulaziz Umar Kurya, Selin Işik, Qendresa Hoti and S. I. Abba
    Citation: Bulletin of the National Research Centre 2022 46:73
    Content type: Research Published on:

  42. Gastrointestinal tract can be compressed by many vascular structures in the abdomen; such compressions may be incidentally found or may result in compression symptoms like abdominal pain and vomiting.

    Authors: Mohammed Tag-Adeen, Abeer Awad Abdellatif, Ahmed Hosni Kamel and Mohamed Alboraie
    Citation: Bulletin of the National Research Centre 2022 46:68
    Content type: Case Report Published on:

  43. Litsea cubeba (Lour) Pers. (Lauraceae) fruit has traditionally been used in treatment of diabetes in Sikkim, India. The purpose of the present study is to investigate the antidiabetic activity of methanol extract...

    Authors: Waquar Ahmed Goldar, Sandipan Jana, Reshma Kumari, Sanjib Bhattacharya and Pallab Kanti Haldar
    Citation: Bulletin of the National Research Centre 2022 46:67
    Content type: Research Published on:

  44. Endocrine disruptors originate from multiple sources making their health impacts enormously complex. This study systematically synthesizes the sources, exposure, and effects of personal care products on reprod...

    Authors: Moses Asori, Julius Odei, Daniel Katey, Truus Apoanaba Abuosi and Razak M. Gyasi
    Citation: Bulletin of the National Research Centre 2022 46:61
    Content type: Review Published on:

  45. Lymphangioma is a multi-systemic disease mostly affecting the mesentery, omentum, mesocolon and retroperitoneum and rarely involving bone, with fewer than 30 cases reported so far. Lymphangioma usually has no ...

    Authors: Hongyi Li, Meng Zhang, Jingzhi Ye, Yanxia Chen and Mengqiang Xiao
    Citation: Bulletin of the National Research Centre 2022 46:58
    Content type: Case Report Published on:

  46. COVID-19 outbreak has engulfed different parts of the world, affecting more than 163 million people and causing more than 3 million deaths worldwide due to human transmission. Thus, it has become critical to i...

    Authors: Arpita Suri, Naveen Kumar Singh and Vanamail Perumal
    Citation: Bulletin of the National Research Centre 2022 46:54
    Content type: Review Published on:

  47. Schizophrenia (SCZ) is a severe mental disorder in which people interpret reality abnormally. Different studies indicated a complex polygenic control over SCZ. In the present study, we investigated the potenti...

    Authors: Ali Molaei, Mohadeseh Agahi, Mahtash Malekian, Bahareh Moradhasel, Ardalan Tajrezaee, Ava Lajevardi, Iman Salahshourifar, Niloufar Mahdavi Hezaveh, Gholamreza Javadi and Zahra Noormohammadi
    Citation: Bulletin of the National Research Centre 2022 46:51
    Content type: Research Published on:

  48. To study variations in biochemical and nutritional profile among children with severe thinness receiving medical nutrition therapy.

    Authors: Varun Viswanathan, Bina Dias, Vishal D. Sawant, Prachi Karnik, Alka Jadhav, Madhubala Jadhav, Blossom Rodrigues and Lavina Fernandes
    Citation: Bulletin of the National Research Centre 2022 46:50
    Content type: Research Published on:

  50. Prostate schistosomiasis is a chronic inflammatory condition of the prostate. In an endemic environment, it may mimic the sinister condition of the prostate in its clinical presentation. Despite the high preva...

    Authors: Abdullahi Khalid, Abdullah Abdulwahab-Ahmed, Ismaila Arzika Mungadi, Kabiru Abdullahi, Ngwobia Peter Agwu and Abubakar Sadiq Muhammad
    Citation: Bulletin of the National Research Centre 2022 46:32
    Content type: Case Report Published on: