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Dyslipidemia and non-alcoholic fatty liver disease are well-known diseases and are part of a very broad spectrum evolving toward non-alcoholic steatohepatitis (NASH). This entity has not been described in preg...
Migraine is a debilitating disorder that undoubtedly has a significant impact both clinically and socially. New treatment options are necessary in Iran due to issues with tolerance, interactions, contraindicat...
Heart transplant recipients are a subset of immunocompromised patients at particularly high risk of morbidity and mortality from COVID-19. Acute effects of the viral infection have been well-described in the l...
Retention in care and adherence to medication among pregnant and breastfeeding women living with HIV (PBWLH) are crucial for preventing mother-to-child transmission (PMTCT) of HIV. Wide coverage of mobile phon...
Weight re-gain (which is also known as re-obesity) is an overwhelming challenge many dieters face in their pursuit to maintain consistent results following successful weight loss. This frustrating pattern of w...
At present, the function of isothermal microcalorimetry (IMC) calscreener in detecting alterations in the metabolic pathways of cancer cells remains unexplored. We disclosed the shortcomings of current screeni...
Methanol poisoning is a worldwide phenomenon that has resulted in deaths and irreversible complications. However, studies show it is more prevalent in developing countries and areas with lower socioeconomic st...
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and challenging cancer for diagnosis and treatment. Accurate diagnosis plays a crucial role guiding appropriate treatment, typically involving hig...
Endometrial carcinosarcomas are rare and carry a very poor prognosis. They usually present with extensive lymphatic spread. An acute presentation of a stroke may reveal the underlying diagnosis.
The protein phosphatase 2 (PP2A) is one of the major serine/threonine phosphatases in humans. The most frequently reported pathogenic PP2A variants have been identified in PPP2R5D, encoding the regulatory subunit...
Central nervous system (CNS) astrocytes have various functions in the central nervous system (CNS). Many neurodegenerative diseases are associated with astrocyte dysfunction.
Systematic review.
In late 2019, coronavirus disease, an acute respiratory illness caused by the novel coronavirus (SARS-CoV-2), was designated COVID-19 and declared a pandemic. The interim guidance for prevention is through vol...
Marburg virus disease (MVD) is a zoonotic viral hemorrhagic illness, caused by a negative sense, single-stranded RNA virus which has an envelope. The Marburg virus belongs to the genus Marburgvirus of the family
Neurosarcoidosis can have various neurological outcomes and presentations. It is an uncommon diagnosis, especially in young Caucasian males presenting with predominantly migraine headaches.
In Egypt, academic organizations, professional societies, and research groups develop clinical practice guidelines (CPGs) in order to improve patient quality care and safety. Although important improvements ha...
This case report documents a rare variation of a persistent median artery. Normally a transient vessel present during embryologic development of the limbs, the median artery typically regresses by the eighth w...
Aim of the observational study was to assess which of the gait and balance parameters are most affected in Parkinson-plus syndromes patients with falling tendencies as compared to healthy individuals.
Low-density lipoprotein cholesterol (LDL-c) is the major determinant of cardiovascular disease burden. This study critically reviewed the published literature and performed a meta-analysis to compare and to de...
Seasonal administration of antimalaria drug, sulphadoxine/pyrimethamine plus amodiaquine to children 3–59 months is a malaria preventive intervention used for the reduction of childhood malaria morbidity and m...
Adults with overweight or obesity have a higher risk of the development of impaired glycemic health and cardiometabolic disorders. Glycemic variability acts as a more sensitive assessment of glycemic health co...
Antimicrobial resistance has already emerged as a major concern not only for public health but also for global economy. It causes a multifaceted crisis in development and growth by increasing the number of inf...
Tuberculosis (TB) is a systemic infectious disease that is caused by Mycobacterium tuberculosis and which can affect many tissues and organs. Despite the development of curative and preventive therapies in rec...
To study incidence of sinonasal mucormycosis in active and post COVID-19 patients in a district-level hospital in India and develop a simplified screening and referral protocol for use at peripheral centres to...
Partial aorta detachment is a rare and fatal complication of mechanical chest compression.
Patients with prostate enlargement have an increased risk of recurrent urinary tract infections. This study determined the resistance profile of bacteria causing urinary tract infection (UTI) and the magnitude...
The END TB 2035 goal has a long way to go in low-income and low/middle-income countries (LICs and LMICs) from the perspective of a non-communicable disease (NCD) control interaction with tuberculosis (TB). The...
The last several years have shed light on the fact that changes in the global climate pose one of the greatest dangers to mankind and life on Earth. Even though a growing amount of attention is being paid to t...
Epididymitis has several etiologies that can be related to infectious and non-infectious causes, autoimmune conditions, aseptic causes, and even certain pharmaceutical medications (amiodarone and chemotherapeu...
Since the outbreak of coronavirus (COVID-19) disease was reported in 2019, huge human and material resources have been expended globally to combat the spread of the disease. Achieving herd immunity through mas...
Hepatitis B virus (HBV) infection continues to be a global public health problem. As of 2019, there were 296 million people chronically infected with HBV, resulting in nearly 1 million deaths from decompensate...
Anti-glomerular basement membrane (GBM) disease and ANCA-associated vasculitis (AAV) diseases are rare. It is associated with variable renal manifestations and increased mortality, thus requiring early aggress...
Neuraxial anesthesia is widely used for labor analgesia in the USA, such as epidural, combined spinal–epidural, and dural puncture epidural (DPE). Post-dural puncture headache (PDPH) is a well-known complicati...
Despite the ongoing onchocerciasis control program that has been in place in Mahenge for more than two decades using the Community Directed Treatment with Ivermectin (CDTI) strategy, the persistent transmissio...
The incidence of mild postoperative complications has been shown to be strongly associated with the beneficial effects provided through minimally invasive surgery. The main objective of the present study was t...
Previous discussions regarding variant femoral nerves often report an aberrant slip of a small portion of the iliacus muscle as a common cause of the femoral nerve splitting. Within these reported cases, the v...
Blinatumomab could be successfully used to reduce minimal residual disease (MRD) prior to hematopoietic stem cell transplantation (HSCT) in pediatric B cell precursor acute lymphoblastic leukemia (BCP-ALL), bu...
Inflammasomes are intracellular multiprotein complexes that sense danger signals from damaged cells and pathogens and assemble to mediate caspase-1 activation, which results in the proteolytic cleavage of pro-...
Unprovoked spontaneous uterine rupture in a primigravid unscarred uterus is a rare but serious obstetric complication. Our case highlights a prelabour uterine rupture in a primiparous patient with an anterior ...
Previous studies have shown significant differences and lack clarity on whether resistance to either isoniazid or rifampicin can predict multidrug resistance tuberculosis (MDR-TB). Some consider rifampicin res...
Manganese (Mn) and Selenium (Se) deficiencies are noted in adult patients with chronic kidney disease (CKD). However, levels of these trace elements have not been well studied in the paediatric CKD population....
Persistent pain after total hip arthroplasty (THA) is a real concern for the surgeon and is a significant cause of patient dissatisfaction; periprosthetic joint infection (PJI), aseptic loosening, and instabil...
Caffeine intake has been positively or negatively associated with the risk of chronic disease. Genome-wide association studies identified single-nucleotide polymorphisms (rs2472297 and rs2470893) in Cytochrome...
In the current global scenario, the monkeypox virus has infected over 3000 individuals from endemic countries like Nigeria, along with non-endemic countries like the UK, Canada, the USA, etc. Based on the curr...
Primary hypertriglyceridemia (HTG) is a very rare autosomal recessive disorder caused by the mutations of the genes related with triglyceride metabolism, including apolipoproteins and lipoprotein lipase (LPL) ...
The Correction to this article has been published in Bulletin of the National Research Centre 2023 47:26
Acinetobacter baumannii is recognized as a major threat that causes healthcare-associated infections and causes a huge challenge to the health system worldwide. This research study was designed to detect the type...
Pulmonary rehabilitation (PR) has proven to improve the physical and psychosocial function in patients with chronic obstructive pulmonary disease (COPD). However, the gains achieved during pulmonary rehabilita...
Antimicrobial resistance is a global problem and involve pathogens which have the potential to move between food producing animals and humans by direct exposure or through the food chain or the environment. Th...
Selective androgen receptor modulators (SARMs) are becoming increasingly common amongst athletes and the general population, but their side effect profile in human subjects at recreational doses is understudied.
