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Global research trends of the studies on Murraya koenigii (L.) spreng: a Scopus-based comprehensive bibliometric investigation (1965–2023)



Murraya koenigii (L.) Spreng. has several well-established nutritional and therapeutic applications. Following our desire to investigate the global and scientific community's knowledge of medicinal plants, this study was intended to examine the evolution of knowledge related to M. Koenigii studies. The primary purpose of this paper is to clarify the status of these studies, investigate their methods, findings, and trends, and define their significance within the current research landscape.


To achieve these goals, bibliometric analysis was conducted, retrieving, and analyzing 934 original articles published between 1965 and 2023 based on Scopus Dataset results. Data were exported as CVS (comma-separated values) and BibTex files and analyzed using Bibliometrix and VOSviewer software. Articles from 502 sources have been identified, averaging 21.8 citations per document. The research in this plant has had exponential growth (R2 = 0.77). International co-authorship is 13.08%. India and Malaysia are the top publishing countries. Debajo, A.C. (Nigeria), Phatak,R.S. (India), and Sukari,M.A. (Malaysia) are the most productive authors. The top source is the Journal of Ethnopharmacology. "Green synthesis," "nanoparticles," "oxidative stress," "Asian citrus psyllid," "apoptosis," "antimicrobial," "anticancer," "Chromatographic profile," "bioactive compounds," and "alkaloids" are strongly related to the current trends in M. Koenigii research. Regarding the specialized topics, M. Koenigii's study concentrated on using this plant as an antioxidant agent in manufacturing and biological systems. Dynamic subjects like chromatographic profiles, essential oils, and Asian citrus psyllids were included in the motor theme.


The current study used bibliometric techniques to evaluate research on M. Koenigii and identify trends and potential future research hot spots.


Curry leaf tree, or Murraya koenigii, was a small tree or shrub that grew up to a height of 6 m and belonged to the family Rutaceae. It was found in tropical and subtropical regions. Countries such as India, Bangladesh, and Sri Lanka all have it in their populations. Ayurveda, the traditional medical practice of India, makes use of almost every part of this plant to treat a wide variety of conditions. These parts include the plant's fresh leaves, fruits, bark, and roots. In traditional medicine, green curry leaves were frequently utilized for the treatment of piles, inflammation, itching, fresh cuts, dysentery, and edema. While the bark was helpful in treating snakebites, the roots were traditionally used to alleviate pain throughout the body (Aniqa et al. 2022; Bhupatiraju et al. 2023; Husna et al. 2018; Mondal et al. 2022b; Singh et al. 2023; Tan et al. 2022). Even after drying, dried M. Koenigii leaves maintain their recognizable aroma, as well as their slightly spicy and somewhat astringent flavor profiles. M. Koenigii both fresh and dried are widely used in South Indian cooking as a seasoning and flavoring agent and are considered to be an essential ingredient in the cuisine of that region (El-Shiekh et al. 2023; Sablania et al. 2023; Singh et al. 2023).

Chromatographic and spectroscopic methods identified many structurally diverse natural products from M. Koenigii leaves, roots, stem bark, fruits, and seeds. In phytochemical studies for biologically active constituents, terpenoids, alkaloids, flavonoids, coumarins, polyphenols, and essential oils were isolated (Balakrishnan et al. 2020). M. Koenigii contains over fifty carbazole-type alkaloids with potent pharmacological activities. Major alkaloids koenimbine, mahanimboline, mahanine, murrayafoline, mahanimbine, isomahanine, murrayazoline, koenoline, mahanimboline, and mukoline were cytotoxic (Abeysinghe et al. 2021a; Balakrishnan et al. 2020). Mahanimbinine, murrayacinine, isomahanine, and mahanimbine were antimicrobial, antioxidant, antidiabetic, and antihyperlipidemic. In M. Koenigii, antioxidant carbazole alkaloids included mukonicine, murrayanine, koenine, koenigine, mukoeic acid, murrayanol, 9-formyl-3-methylcarbazole, and O-methylmurrayamine A, while antimicrobial alkaloids included murrayanine, murrayacine, mahanine, mukoline, girinimbine, and pyrafolione D. The M. Koenigii non-alkaloidal compounds epicatechin, catechin, quercetin, naringin, myricetin, and rutin were antioxidant and anticancer compounds. Ferulic, vanillic, gallic, and acids also boost M. Koenigii's antioxidant capacity (Aniqa et al. 2022; Bhupatiraju et al. 2023; Husna et al. 2018; Mondal et al. 2022a; Nawrot et al. 2022; Samanta et al. 2018).

Curry leaves were abundant in magnesium, potassium, calcium, and phosphorus, in addition to traces of zinc, manganese, selenium, and iron. In addition, lead, mercury, and cadmium were present. Diverse leaf samples of M. Koenigii were collected from various geographic locations, and due to varying climate, soil, and other geo-environmental conditions, the average elemental contents varied. Changes in plants grown in polluted soils revealed elevated levels of metals, which posed a serious threat to human health because they could affect the kidney, liver, and central nervous system (Abeysinghe et al. 2021b; Nagappan et al. 2012; Narendhirakannan et al. 2005).

M. Koenigii has a number of well-established therapeutic potentials, including hypoglycemic, hypolipidemic, nephroprotective, hepatoprotective, gastroprotective, cardioprotective, atherosclerotic, and cholesterol lowering effects in experimental animals. The alcoholic extract of the leaf possessed antioxidant, analgesic, anti-inflammatory, antipyretic, antitrichomonal, antibacterial, antifungal, antileishmanial, antidiarrheal, wound-healing, anti-obesity, anticancer, and immunomodulatory activities. The carbazole alkaloid mahanine, which was purified from M. Koenigii, acted as a proteasome inhibitor and displayed antihyperglycemic action. These two effects contributed to the mahanine's anticancer activity (Bhupatiraju et al. 2023; Mondal et al. 2022a, 2022b; Nazeer et al. 2022; Ramsewak et al. 1999b; Wadanambi et al. 2023; Wassmuth-Wagner et al. 1995).

Following our interest in exploring the global and scientific community's knowledge of medicinal plants, this paper provides an overview of the knowledge regarding the mechanisms of action and the essential bioactive components present in this plant. This work is also susceptible to the influence of the knowledge produced, its size, and its global dissemination. It also provides a real-time platform for all those interested in traditional medicine to learn about the parties working in this field to facilitate future scientific collaboration. To accomplish this, we utilized bibliometric methods to unearth our intent. Where no such reference is available for this tree. According to our knowledge, this paper is the first to conduct a bibliometric analysis of knowledge and research on this tree.


Database, data acquisition, and querying

The bibliometric study was carried out with the assistance of the Scopus database as a primary source. Scopus is a platform owned by Elsevier and comprises a sizable collection of bibliographic databases, citations, and references from scientific publications in any field of knowledge, including science, technology, social sciences, arts, and humanities (Al-Khoury et al. 2022). Scopus can be accessed through the Elsevier website. The search terms are related to "Murraya koenigii" (title, abstract, or keywords). The study's time frame was 1965–2023. The data were extracted on June 13, 2023. There were only journal articles present. The languages of the documents published are limited to English only. Conference proceedings, articles, books, etc., were also excluded. The procedure flow used to gather data and conduct queries are shown in Fig. 1.

Fig. 1
figure 1

Data search strategy in the Scopus database. ar: article; PUBYEAR: publication year; DOCTYPE: type of the document

Data filtering and sample size

From 1965 to 2024, 1091 M. Koenigii-related works were retrieved from the Scopus database. The researchers identified and analyzed 934 original articles. The final publication date for these papers is 2023. Therefore, all papers published after this date were excluded from the current study. The inclusion of these works in the present research, despite belonging to the same period defined in the search term, may distort the interpretation of the data, and the growth of the analysis because they belong to something other than the calendar year of the period under review. According to the guidelines for bibliometric investigations, any sample size greater than 200 research documents is sufficient to execute a reliable study (Rogers et al. 2020). The final data were exported from the Scopus database as two file types, CVS and Bib format.

Analysis tools: bibliometrix and vosviewer

Open-source tools for quantitative scientometric and bibliometric research that cover all the major bibliometric methods of analyses include Bibliometrix (R Package) and Vosviewer (Oladinrin et al. 2023). These tools enable researchers to study and visualize the various research cooperation networks established or developing patterns in a particular field of knowledge, as well as to highlight the most pertinent documents, journals, nations, authors, and institutions. Bibliometrix (R Package) and Vosviewer have been used in a number of studies. Research in the areas of biology, artificial intelligence (Hou and Yu 2023), Pharmacology (Abdelwahab et al. 2023; Ge et al. 2022; Li et al. 2022; Wang et al. 2022), and social research (Hou and Yu 2023) and data science (Nobanee 2021) are a few examples.


Main information about the collection

The main findings of the analysis—document type, document content, and author collaboration—are presented in Table 1. With 934 documents total and an average of 21.8 citations per document, the study covers the years 1965 to 2023. The study has shown that articles in 502 scientific sources. Only 2532 of the 8971 keywords used in the study sample were used by authors, out of all the works that make up the study sample. It should be noted that this kind of publication contains relatively few single authors. Thirt-three of the 934 recovered works were written by just one author. The total number of scholars who participated to the literature of this tree is 3047.

Table 1 Main information

Country, affiliation, and author scientific production

Figure 2 shows the distribution of scientific production frequencies worldwide by the affiliation country. A total of 66 countries have contributed to the publication of journal articles on M. Koenigii-related works. Within the top 5, we appreciate how India in 1st position (1167 freq.) and the Malaysia in 2nd position (192 freq.) stands out on the hegemony of academic-scientific production, followed in the 3rd position by the USA (60 freq.), in 4th position Pakistan (58 freq.) and 5th position China (53 freq.). Universiti Putra Malaysia, Universiti Teknologi MARA, (Malaysia), Bose Institute, University of Calcutta, Central Drug Research Institute (India) had the highest number of published articles on M. Koenigii. Debajo, A.C. (Obafemi Awolowo University, Nigeria), Phatak, R.S. (Deemed University, India), and Sukari, M.A. (Universiti Putra Malaysia, Malaysia) are the highest productive authors with nine documents for each.

Fig. 2
figure 2

Country production. The map illustrates the scientific productivity attributed to the plant under investigation in the research. The aforementioned figure was generated with the Bibliometrix program. There exists a positive correlation between the intensity of the blue hue and the level of scientific productivity

Figure 3 shows the annual production volume (1965–2023) of research on M. Koenigii. The research in this area has experimented an exponential growth (R2 = 0.77). In descending order: 2022 (with 72 articles published), 2012 and 2021 (61 articles), 2011 (59 articles), 2015 (58 articles), and 2014 (56 articles).

Fig. 3
figure 3

Annual scientific production related to M. Koenigii. The figure was generated using MS-Excel (n = 934). The data were extracted on June 13, 2023

Three field plot

Observing the trends in the study topics, countries, and states of M. Koenigii publications in addition to the annual production is crucial. Author keywords are in the center of Fig. 4, authors are on the right, and countries are on the left. This Figure shows the threefold examination of M. Koenigii publications. The graph demonstrates that India leads Malaysia, Pakistan, Indonesia, and China regarding top countries for M. Koenigii-related publications. They are researching M. Koenigii with India because it is considered one of the countries where M. Koenigii is planted. When examining the authors' keywords, we find that India has participated in all the research on this plant, as this is evident from the flow we notice in Fig. 4. As for some countries, such as the United Kingdom, their research was limited to a narrow range. Many researchers have studied leaves' biological and chemical properties, such as antioxidant activities, anticancer properties, green synthesis, antibacterial activity, essential oil, and anti-diabetic properties.

Fig. 4
figure 4

Three field plots of country, keyword, and authors. The figure was generated using biblioshiny application in Bibliomtrix and Bib data format (n = 934). AU: author; AU_CO: country of the author: DC: DE: keywords

Table 2 displays the top 20 journals in which the most papers on M. Koenigii were published. The total number of sources is 502. A total number of 934 articles regarding M. Koenigii were published in these journals between 1965 and 2023 and indexed in the Scopus database. The top four journals were the Journal of Ethnopharmacology (22 papers), International Journal Of Pharma And Bio-Sciences (18 documents), Phytochemistry (14 documents), and Asian Journal Of Chemistry (12 documents). Although the Journal of Ethnopharmacology has the highest number of citations, Food Chemistry and the Journal Of Agricultural And Food Chemistry have the highest average of citations. This means that the research published in these two journals has a more cognitive impact than those published in the first.

Table 2 Top publishing sources according to Scopus database

Trendy topics

Trendy topics have evolved over the last 60 years, as shown in Fig. 5. The analysis of trendy topics was performed in Bibliometrix applications using keywords. Keywords such as "green synthesis," "nanoparticles," "oxidative stress," "anti-diabetic," "Asian citrus psyllid," "apoptosis," "antimicrobial," "anticancer," "HPLC," "bioactive compounds," "phytochemicals," and "alkaloids" are strongly related to the current trends in M. Koenigii research. The term frequency is shown in blue circles (Fig. 5), and the time span of the keyword is shown in the horizontal line. The term "Rutaceae" has the most extended shelf life.

Fig. 5
figure 5

Trending topics. The figure was generated using biblioshiny application in Bibliometrix and BibTex data format (n = 934). Blue circles denote the term frequency, and a horizontal line displays the term's time range. The phrase "Rutaceae" has the longest expiration date

Thematic map

The thematic map divides the majority of topics into two groups: motor themes and fundamental themes, both of which have a high centrality but a low density. The basic and motor topics have a lot of potential, and researchers can successfully pursue them. The specialized and motor themes' topics are frequently covered in great detail in the M. Koenigii literature. Though they have been examined, the worries in the case of M. Koenigii have not fully developed. Due to the research that has been done and the requirement for more effort, this problem is moving from emergent to basic. The phrase "Huanglongbing (yellow dragon disease)," which is both an emerging subject and one of the core ideas, is one such example. Therefore, there is a clear need for more research. Figure 6 depicts where the themes are located. These themes are generated through clustering. A bibliometric analysis and enrichment method is clustering. Its main objective is to organize network clusters into topic clusters, track these topic clusters' development, and understand how a study field emerges and changes. Antioxidant activity, antibacterial activity, diabetes, oxidative stress, and carbazole alkaloids were the main themes. Regarding the specialized topics, M. Koenigii's study concentrated on using this plant as an antioxidant agent in manufacturing and biological systems. Dynamic subjects like HPLC profile, essential oil, and Asian citrus psyllid were included in the motor theme. No matter where the research on M. Koenigii is conducted, it is clustered in Table 3. There were discovered 14 clusters, which included Asian citrus psyllid, Acacia nilotica, Huanglongbing, Psidium guajava, and host plant. Other clusters included curry leaves, Murraya koenigii, medicinal plants, Rutaceae, free radical scavenging activity, mild steel, HPLC, and anti-inflammatory.

Fig. 6
figure 6

Thematic map. The figure was generated using biblioshiny application in Bibliometrix and Bib data format (n = 934). The degree of relevance and development is used to split the figure into four quadrants. Or, to put it another way, based on the degree of density and centrality. More developed and relevant motor themes are thought to be

Table 3 Clustering of thematic structure*

Thematic evolution

The topic development of M. Koenigii literature since 1965 is seen in Fig. 7. Using the author's keywords, the thematic progression demonstrates the development of topics through time. One-time breaks lead to two-time segments, and "biblioshiny" is used to develop thematically. To preserve a more realistic image of the issue's progression, the researcher's judgment will choose how to divide the time period. The first section covers the years 1965 through 2014 and the second, 2015 through 2023. Over time, themes developed. The primary focus of M. Koenigii research has always been ethnopharmacological findings. Analysis shows that from 1965 to 2014, the studies began to include medicinal properties of the plant and it’s pure compounds including anti-inflammatory, antioxidant, antifungal, antinociception, and ethnobotanical studies. As a result, research on M. Koenigii shows an increasing tendency until 2022. From 2015 forward, the research on this tropical tree has advanced dramatically. The topics were more versatile. Researchers have explored new areas such as pure compound isolation, phytochemical screening, identity of curry leaves as spice, green chemistry, spray drying, biological activities of girinimbine, and mahanine, and mild steel. Figure 8 was generated by utilizing the VOSviewer program for the years 2015 through 2023 for the purpose of delving more into the dynamics of knowledge and locating research subjects that have surfaced more lately. According to the indicator that is located next to Fig. 8, recently discussed subjects include programmed cell death and green synthesis.

Fig. 7
figure 7

Thematic evolution. The figure was generated using biblioshiny application in Bibliometrix and Bib data format (n = 934).Bigger boxes show the strength of the terms. The lines represent the intellectual correspondence link between the terms

Fig. 8
figure 8

Overlay visualization for the past fifteen years of author’s keywords. Mapping was generated VOSviewer for the years 2015 through 2023 for the purpose of delving more into the dynamics of knowledge and locating research subjects that have surfaced more lately. The shapes represent the number of documents. The lines represent the intellectual correspondence link between the terms. The bar represents the temporal analysis of the keyword and their

Social analysis: co-authorship analysis

VOSviewer was used to assess the collaborative research globally. A total of 66 countries have contributed to the publication of journal articles on M. Koenigii-related works. Six clusters were mapped for 23 countries, which met the criteria of minimum number 5 documents (Fig. 9). India possessed the largest node in the red cluster with Total Link Strength of 52. Indian institutions collaborated significantly with Bangladesh, Pakistan, China, Australia, Canada, and Spain. Four countries formed the green cluster with Malaysia as the strongest collaborator. Germany, United States, UK, Saudi Arabia are the top collaborators in the blue, yellow, purple clusters, respectively. Biblioshiny parameters for author’s collocation are shown in Table 1.

Fig. 9
figure 9

International collaboration. VOSviewer mapping of the top 23 documents with more than five documents was performed. The shapes represent the number of documents. The lines represent the collaboration link between the countries. Countries with the same color had more collaboration among them

Impactful research: citation analysis

The total number of citations for all 934 is 20,366, with an H-index of 68 (Fig. 8). The H-index of 68 is marked by the yellow star (Fig. 10). Table 4 lists the most cited documents, their journals, citations, and citation average in regard to research on M. Koenigii between 1965 and 2023. The article "Antioxidant Activities of Aqueous Extracts of Selected Plants" received the highest number of citations (621) and citation average (36.53). The Journal of Ethnopharmacology and Food Chemistry score the highest citation numbers with 2012 and 1274, respectively. The Department of Pharmacognosy, Faculty of Pharmacy, Obafemi Awolowo University, Nigeria, received a score of 275, followed by the Central Drug Research Centre, India (n = 134). India, Malaysia, and the USA had citation numbers of 13000, 2087, and 1041, respectively.

Fig. 10
figure 10

Citation score (H-index = 68). Figure was generated using Scopus Analytics feature. High h-index is characterized by having published a minimum number of works that have received an equal or greater number of citations

Table 4 The most cited documents


This paper examines studies' status, issues, methodologies, findings, and trends, as well as their relevance to current research related to M. Koenigii. Using Scopus Database findings, bibliometric analysis was performed on 934 publications published between 1965 and 2023. It has not been established in any of the previously conducted study that this plant, which is notable for its beneficial effects on both nutrition and health, has been the subject of any bibliometric investigations into the dynamics of existing knowledge or the identification of potential research topics.

The curry tree, also known as M. Koenigii or Bergera koenigii, is a species of tree that is endemic to Asia and may be found growing in both tropical and subtropical climates. The highest amount of articles devoted to studying this plant has come out of Asia, specifically from countries like India and Malaysia. This could be due to the fact that the tree originated in these nations, its widespread usage in medicine and cooking, and the fact that these countries make use of the collected research experience. Research in nations outside of Asia, including Nigeria, the United States, and the United Kingdom, has also demonstrated the plant's significance. Adebajo, A.C., a Nigerian researcher, accumulated a substantial body of knowledge about the curry tree. The biochemical, pharmacological, phytochemical, and toxicological activities of crude extract and some alkaloids obtained from the leaves of M. Koenigii grown in Nigeria were studied by him and his team from the Department of Pharmacognosy, Faculty of Pharmacy, Obafemi Awolowo University, Nigeria (Adebajo et al. 2006, 2009, 2014; Adebajo and Reisch 2000; Reisch et al. 1994).

The top journal in the dissemination of M. Koenigii research is the Journal of Ethnopharmacology. Nearly all of this plant's parts are used in Ayurveda, the Indian system of traditional medicine, to cure a wide range of ailments. The plant's new leaves, fruits, bark, and roots are among these components. Green curry leaves were commonly used in traditional medicine to treat piles, inflammation, itching, new cuts, diarrhea, and edema. While the roots were traditionally used to cure generalized pain, the bark proved useful for healing snakebites (Adebajo et al. 2009; Jain et al. 2017; Tan et al. 2022). About 30% of the papers published in the journal were ethnobotanical studies on this tree (Aniqa et al. 2022; Bhupatiraju et al. 2023; Husna et al. 2018; Kamsani et al. 2020; Mondal et al. 2022b; Singh et al. 2023). At the same time, the remaining number (16/22) reviewed experimental studies on many biological properties of this plant. Food Chemistry is the most impactful journal in M. Koenigii research as demonstrated in Table 2 with citation average of 115.82. This journal accommodated various articles on the antioxidant properties of this plant (Biswas et al. 2012; Choudhury and Garg 2007; Ningappa et al. 2008; Raju et al. 2007; Rao et al. 2007; Wong et al. 2006). It is generally known that consuming more vegetables and medicinal herbs along with antioxidants lowers the chance of developing certain ailments (Zahin et al. 2013). The dietary use of this plant may explain the research interest in its antioxidant properties and the intensity of studies on this property.

Trendy topics have evolved over the last 60 years, as shown in Fig. 5. Publication keywords are frequently employed to expose the knowledge structure of study domains and are regarded as the fundamental components of conveying knowledge concepts in bibliometric research. Research topic analysis based on co-word clustering, knowledge mapping based on co-word networks, and hotspot discovery and trend analysis based on keyword frequency analysis are all covered in related studies (Aniqa et al. 2022; Bhupatiraju et al. 2023; Husna et al. 2018; Mondal et al. 2022b; Singh et al. 2023). The latest trending topics in M. Koenigii research are green synthesis and nanoparticles. In the field of phytochemistry, biogenetically manufacturing nanoparticles from plant derivatives and exploring their potential for usage as novel therapeutics has been one of the hot research issues. The focus of current research on nanoparticles is the range of applications for green synthesis (Shreyash et al. 2021). In recent studies, green chemistry was used to synthesize zinc oxide nanoparticles using zinc nitrate and the bioactive ingredients in M. Koenigii leaf extract (Lakshmikandhan 2020; Qais et al. 2019). One of the important topics that will shape future research on this tree is green synthesis. This can be linked to the fact that this tree began to enter other environmental ranges and leave its original habitat. The tree is tropical or subtropical and indigenous to Bangladesh, India, and Pakistan. More recently, in Australia, commercial plantations have been built. It is grown throughout tropical Africa in nations like Nigeria, Kenya, Tanzania, and the majority of the islands in the Indian Ocean, where Indian immigrants landed (Adebajo et al. 2006, 2009, 2014, 2004; Adebajo and Reisch 2000; Balakrishnan et al. 2020; Nazeer et al. 2022; Panda 2014; Sharma et al. 2013).

In this study, we used bibliometric analysis to explore the intellectual structure of M. Koenigii literature. The majority of topics are divided into two groups on the thematic map: motor themes and fundamental themes, both of which have a high centrality but low density. Basic and motor topics have great potential, and researchers can pursue them successfully. In the literature on M. Koenigii, the specialized and motor themes are frequently and thoroughly discussed. Fourteen clusters were generated using author’s keywords. These clusters were divided into four themes to represent the intellectual structure of M. Koenigii literature. Knowing the knowledge structure of any research field helps researchers and decision-makers shape the future and current map for this research field and save effort and money (Karakose et al. 2022). Global evaluation of the collaborative research was done using VOSviewer. Significant collaboration took place between Indian institutions and Bangladesh, Pakistan, China, Australia, Canada, and Spain. Phytochemistry is a multi- and inter-disciplinary field of study that focuses on the chemical compounds produced by plants, particularly secondary metabolites, as well as their structural formulations, biosynthetic pathways, functions, mechanisms of action, and applications. Historically, bibliometric techniques were used to quantitatively obtain a structural overview of research collaboration (Wilson 2022).

Measuring scientific output is a more involved and consequential task than at first glance. Many other approaches have been offered for quantitative analysis, but none of them are without flaws. Analysis of the frequency with which a given article, author, or institution is mentioned by other works or writers is known as a "citation analysis" (Cariveau et al. 2020). According to the established definition, an author or journal with a high h-index is characterized by having published a minimum number of works that have received an equal or greater number of citations. The h-index is not a complicated concept to understand. Simply plot the number of papers published against the number of citations received, and the h-index is the point at which the 45-degree line (citations = papers) intersects the curve. The h-index is useful because it provides a single metric that takes into account both productivity (the number of papers published) and impact (the number of citations). Therefore, a high h-index requires both production and impact; having either a small number of highly cited publications or a large number of papers with few (or no) citations will not provide a high h-index (Bertran et al. 2020). 20,366 citations and 68 H-indexes for all 934 (Fig. 8). Yellow stars indicate 68 H-index. Table 4 shows the 1965–2023 M. Koenigii research papers with the most citations, journals, and citation averages. "Antioxidant Activities of Aqueous Extracts of Selected Plants" has the most citations (621) and average (36.53). It was discovered that the leaves of M. Koenigii exhibit the highest levels of antioxidant activity as well as total phenolic content (Bhupatiraju et al. 2023; Mondal et al. 2022b; Nazeer et al. 2022; Singh et al. 2023).


This study, which offered thorough data on the intellectual development, influence of knowledge, and performance of M. Koenigii literature, had certain drawbacks. First off, our data set only included Scopus-indexed journal articles; it did not include books or book chapters, dissertations, or conference proceedings. Despite Scopus' extensive coverage of high-impact journals, our study may have unintentionally left out certain crucial studies. Second, as implied by its methodology, the study is distinct from conventional review studies. As a result, the results do not correspond to those of earlier studies but rather demonstrate the bibliometric and evolutionary characteristics of the literature on M. Koenigii in accordance with the study of meta-data related to these studies. Our study still has the potential to lay the groundwork for upcoming analyses and investigations into M. Koenigii by defining the thematic progression of the subject field.


The current study employed a broad investigation into the scientific evolution of M. Koenigii research field, and exhibited the intellectual and conceptual architecture of the knowledge related to this plant established during the last six decades. Despite the fact that the methodology used in this study establishes the value of this tree from a medicinal and dietary standpoint, it also creates a crucial framework for future investigations in the search for novel pharmacological values, particularly by highlighting the primary research topics and encouraging the continuation of research in the areas under investigation. A major implication of the current study is that, despite the breadth and extent of research on this tree, it is promising as a comparative source for many botanical studies. Based on this result, we believe that research in this field is still in its infancy, although the distributed perspective has made great inroads in medicinal plant research. The study spans the years 1965 through 2023, with a total of 934 documents and an average of 21.8 citations per document. India and Malaysia are the top-publishing countries. Debajo, A.C. (Nigeria), Phatak, R.S. (India), and Sukari, M.A. (Malaysia) are the highest productive authors. The top source is the Journal of Ethnopharmacology. Regarding the specialized topics, M. Koenigii's study concentrated on using this plant as an antioxidant agent in manufacturing and biological systems. Dynamic subjects like HPLC profile, essential oil, and Asian citrus psyllid were included in the motor theme. In conclusion, filling these study gaps in this plant research would make a significant contribution to our optimal exploitation of it in terms of health and nutrition. Additionally, it would advance the knowledge base to a more mature stage, which can also be examined in future scientific mapping studies.


There are certain limitations to the present research. Even though the author tried his utmost to minimize this sort of inaccuracy, false-positive and false-negative outcomes are possible. Furthermore, the use of Scopus to retrieve documents may have resulted in the loss of certain papers published in non-English nations' natively unindexed journals. The proportion of papers connected to M. Koenigii that focused on non-English studies was 0.22%.

Availability of data and materials

The datasets used and/or analyzed during the current study available from the corresponding author on reasonable request.


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  • Abdelwahab SI, Taha MME, Moni SS, Alsayegh AA (2023) Bibliometric mapping of solid lipid nanoparticles research (2012–2022) using VOSviewer. Med Novel Technol Dev 17:100217

    Article  Google Scholar 

  • Abeysinghe DT, Alwis D, Kumara KAH, Chandrika UG (2021a) Nutritive importance and therapeutics uses of three different varieties (Murraya Koenigii, Micromelum Minutum, and Clausena Indica) of curry leaves: an updated review. Evidence-Based Complem Alternat Med Ecam 2021:5523252

    CAS  Google Scholar 

  • Abeysinghe DT, Kumara KAH, Kaushalya KAD, Chandrika UG, Alwis D (2021b) Phytochemical screening, total polyphenol, flavonoid content, in vitro antioxidant and antibacterial activities of Sri Lankan varieties of Murraya koenigii and Micromelum minutum leaves. Heliyon 7(7):e07449

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Adebajo AC, Ayoola OF, Iwalewa EO, Akindahunsi AA, Omisore NO, Adewunmi CO, Adenowo TK (2006) Anti-trichomonal, biochemical and toxicological activities of methanolic extract and some carbazole alkaloids isolated from the leaves of Murraya koenigii growing in Nigeria. Phytomed Int J Phytother Phytopharmacol 13(4):246–254

    CAS  Google Scholar 

  • Adebajo AC, Iwalewa EO, Obuotor EM, Ibikunle GF, Omisore NO, Adewunmi CO, Obaparusi OO, Klaes M, Adetogun GE, Schmidt TJ, Verspohl EJ (2009) Pharmacological properties of the extract and some isolated compounds of Clausena lansium stem bark: anti-trichomonal, antidiabetic, anti-inflammatory, hepatoprotective and antioxidant effects. J Ethnopharmacol 122(1):10–19

    Article  CAS  PubMed  Google Scholar 

  • Adebajo AC, Odediran SA, Aliyu FA, Nwafor PA, Nwoko NT, Umana US (2014) In vivo antiplasmodial potentials of the combinations of four nigerian antimalarial plants. Molecules (basel, Switzerland) 19(9):13136–13146

    Article  PubMed  Google Scholar 

  • Adebajo AC, Olayiwola G, Verspohl JE, Iwalewa EO, Omisore NOA, Bergenthal D, Kumar V, Adesina SK (2004) Evaluation of the ethnomedical claims of Murraya koenigii. Pharm Biol 42(8):610–620

    Article  CAS  Google Scholar 

  • Adebajo AC, Reisch J (2000) Minor furocoumarins of Murraya koenigii. Fitoterapia 71(3):334–337

    Article  CAS  PubMed  Google Scholar 

  • Al-Khoury A, Hussein SA, Abdulwhab M, Aljuboori ZM, Haddad H, Ali MA, Abed IA, Flayyih HH (2022) Intellectual capital history and trends: a bibliometric analysis using Scopus database. Sustainability 14(18):11615

    Article  Google Scholar 

  • Aniqa A, Kaur S, Sadwal S (2022) A review of the anti-cancer potential of Murraya koenigii (Curry Tree) and its active constituents. Nutr Cancer 74(1):12–26

    Article  PubMed  Google Scholar 

  • Balakrishnan R, Vijayraja D, Jo SH, Ganesan P, Su-Kim I, Choi DK (2020) Medicinal profile, phytochemistry, and pharmacological activities of Murraya koenigii and its primary bioactive compounds. Antioxidants (Basel, Switzerland) 9(2):568

    Google Scholar 

  • Benalla W, Bellahcen S, Bnouham M (2010) Antidiabetic medicinal plants as a source of alpha glucosidase inhibitors. Curr Diabetes Rev 6(4):247–254

    Article  CAS  PubMed  Google Scholar 

  • Bertran K, Cortey M, Díaz I (2020) The use of H-index to assess research priorities in poultry diseases. Poult Sci 99(12):6503–6512

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Bhupatiraju L, Bethala K, Wen Goh K, Singh Dhaliwal J, Ching Siang T, Menon S, Menon B, Anchu KB, Yee Chan S, Chiau Ming L, Khan A (2023) Influence of Murraya koenigii extract on diabetes induced rat brain aging. J Med Life 16(2):307–316

    Article  PubMed  PubMed Central  Google Scholar 

  • Biswas AK, Chatli MK, Sahoo J (2012) Antioxidant potential of curry (Murraya koenigii L.) and mint (Mentha spicata) leaf extracts and their effect on colour and oxidative stability of raw ground pork meat during refrigeration storage. Food Chem 133(2):467–472

    Article  CAS  PubMed  Google Scholar 

  • Cariveau T, Robbins H, Cividini-Motta C, Delfs C (2020) Citation analysis of the analysis of verbal behavior (2008–2018). Anal Verbal Behav 36(1):87–101

    Article  PubMed  PubMed Central  Google Scholar 

  • Choudhury RP, Garg AN (2007) Variation in essential, trace and toxic elemental contents in Murraya koenigii-a spice and medicinal herb from different Indian states. Food Chem 104(4):1454–1463

    Article  CAS  Google Scholar 

  • Devatha CP, Thalla AK, Katte SY (2016) Green synthesis of iron nanoparticles using different leaf extracts for treatment of domestic waste water. J Clean Prod 139:1425–1435

    Article  CAS  Google Scholar 

  • El-Shiekh RA, Kassem HA, Khaleel AE, Abd El-Mageed MM (2023) Anticholinesterases activity of Murraya koenigii (L.) Spreng. and Murraya paniculata (L.) Jacq. essential oils with GC/MS analysis and molecular docking. Nat Product Res 5:1–5

    Google Scholar 

  • Ge Y, Chao T, Sun J, Liu W, Chen Y, Wang C (2022) Frontiers and hotspots evolution in psycho-cardiology: a bibliometric analysis from 2004 to 2022. Curr Probl Cardiol 47(12):101361

    Article  PubMed  Google Scholar 

  • Hou Y, Yu Z (2023) A bibliometric analysis of synchronous computer-mediated communication in language learning using VOSviewer and CitNetExplorer. Educ Sci 13(2):125

    Article  Google Scholar 

  • Huda-Faujan N, Noriham A, Norrakiah AS, Babji AS (2009) Antioxidant activity of plants methanolic extracts containing phenolic compounds. Afr J Biotechnol 8(3):484–489

    CAS  Google Scholar 

  • Husna F, Suyatna FD, Arozal W, Poerwaningsih EH (2018) Anti-diabetic potential of Murraya Koenigii (L.) and its antioxidant capacity in nicotinamide-streptozotocin induced diabetic rats. Drug Res 68(11):631–636

    Article  CAS  Google Scholar 

  • Jain M, Gilhotra R, Singh RP, Mittal J (2017) Curry leaf (Murraya koenigii): a spice with medicinal property. MOJ Biology and Medicine 2(3):236–256

    Google Scholar 

  • Kamsani K, Franco FM, Slik F (2020) A comparative account of the traditional healing practices of healers and non-healers in the Kiudang area of Brunei Darussalam. J Ethnopharmacol 5:256

    Google Scholar 

  • Karakose T, Papadakis S, Tülübaş T, Polat H (2022) Understanding the intellectual structure and evolution of distributed leadership in schools: a science mapping-based bibliometric analysis. Sustainability 14(24):16779

    Article  Google Scholar 

  • Lakshmikandhan T (2020) Green synthesis of zinc oxide nanoparticles using murraya koenigii (curry leaf) leaf extract. Malaya J Matematik 2:4309–4317

    Google Scholar 

  • Li D, Yu D, Li Y, Yang R (2022) A bibliometric analysis of PROTAC from 2001 to 2021. Eur J Med Chem 244:114838

    Article  CAS  PubMed  Google Scholar 

  • Mondal P, Natesh J, Abdul Salam AA, Meeran SM (2022a) Mahanimbine isolated from Murraya koenigii inhibits P-glycoprotein involved in lung cancer chemoresistance. Bioorg Chem 129:106170

    Article  CAS  PubMed  Google Scholar 

  • Mondal P, Natesh J, Penta D, Meeran SM (2022b) Extract of Murraya koenigii selectively causes genomic instability by altering redox-status via targeting PI3K/AKT/Nrf2/caspase-3 signaling pathway in human non-small cell lung cancer. Phytomed Int J Phytother Phytopharmacol 104:154272

    CAS  Google Scholar 

  • Nagappan T, Ramasamy P, Vairappan CS (2012) Chemotaxonomical markers in essential oil of Murraya koenigii. Nat Prod Commun 7(10):1375–1378

    CAS  PubMed  Google Scholar 

  • Narendhirakannan RT, Subramanian S, Kandaswamy M (2005) Mineral content of some medicinal plants used in the treatment of diabetes mellitus. Biol Trace Elem Res 103(2):109–115

    Article  CAS  PubMed  Google Scholar 

  • Nawrot J, Gornowicz-Porowska J, Budzianowski J, Nowak G, Schroeder G, Kurczewska J (2022) Medicinal herbs in the relief of neurological, cardiovascular, and respiratory symptoms after COVID-19 infection a literature review. Cells 11(12):56

    Article  Google Scholar 

  • Nazeer HY, Iqbal MO, Mumtaz A, Ahmed MM, Riaz R, Rasool MF (2022) In vivo antioxidants, chemical characterization and biochemical and medicinal potential of Murraya koenigii in cisplatin-induced nephrotoxicity. Drug Dev Ind Pharm 48(10):566–574

    Article  CAS  PubMed  Google Scholar 

  • Ningappa MB, Dinesha R, Srinivas L (2008) Antioxidant and free radical scavenging activities of polyphenol-enriched curry leaf (Murraya koenigii L.) extracts. Food Chem 106(2):720–728

    Article  CAS  Google Scholar 

  • Nobanee H (2021) A bibliometric review of big data in finance. Big Data 9(2):73–78

    Article  PubMed  Google Scholar 

  • Oladinrin OT, Arif M, Rana MQ, Gyoh L (2023) Interrelations between construction ethics and innovation: a bibliometric analysis using VOSviewer. Constr Innov 23(3):505–523

    Article  Google Scholar 

  • Panda SK (2014) Ethno-medicinal uses and screening of plants for antibacterial activity from Similipal Biosphere Reserve, Odisha, India. J Ethnopharmacol 151(1):158–175

    Article  PubMed  Google Scholar 

  • Philip D, Unni C, Aromal SA, Vidhu VK (2011) Murraya Koenigii leaf-assisted rapid green synthesis of silver and gold nanoparticles. Spectrochim Acta Part A Mol Biomol Spectrosc 78(2):899–904

    Article  ADS  Google Scholar 

  • Qais FA, Shafiq A, Khan HM, Husain FM, Khan RA, Alenazi B, Alsalme A, Ahmad I (2019) Antibacterial effect of silver nanoparticles synthesized using Murraya koenigii (L.) against multidrug-resistant pathogens. Bioinorganic Chem Appl 5:4649506

    Google Scholar 

  • Quraishi MA, Singh A, Singh VK, Yadav DK, Singh AK (2010) Green approach to corrosion inhibition of mild steel in hydrochloric acid and sulphuric acid solutions by the extract of Murraya koenigii leaves. Mater Chem Phys 122(1):114–122

    Article  CAS  Google Scholar 

  • Raju M, Varakumar S, Lakshminarayana R, Krishnakantha TP, Baskaran V (2007) Carotenoid composition and vitamin A activity of medicinally important green leafy vegetables. Food Chem 101(4):1598–1605

    Article  CAS  Google Scholar 

  • Ramsewak RS, Nair MG, Strasburg GM, DeWitt DL, Nitiss JL (1999a) Biologically active carbazole alkaloids from Murraya koenigii. J Agric Food Chem 47(2):444–447

    Article  CAS  PubMed  Google Scholar 

  • Rao LJM, Ramalakshmi K, Borse BB, Raghavan B (2007) Antioxidant and radical-scavenging carbazole alkaloids from the oleoresin of curry leaf (Murraya koenigii Spreng.). Food Chem 100(2):742–747

    Article  CAS  Google Scholar 

  • Rehana D, Mahendiran D, Kumar RS, Rahiman AK (2017) Evaluation of antioxidant and anticancer activity of copper oxide nanoparticles synthesized using medicinally important plant extracts. Biomed Pharmacother 89:1067–1077

    Article  CAS  PubMed  Google Scholar 

  • Reisch J, Adebajo AC, Aladesanmi AJ, Adesina KS, Bergenthal D, Meve U (1994) Chemotypes of Murraya koenigii growing in Sri Lanka1. Planta Med 60(3):295–296

    Article  CAS  PubMed  Google Scholar 

  • Rogers G, Szomszor M, Adams J (2020) Sample size in bibliometric analysis. Scientometrics 125(1):777–794

    Article  Google Scholar 

  • Sablania V, Basak S, Bosco SJD (2023) Effect of spray drying on physical, structural, and functional properties of Murraya koenigii leaf extract. J Food Measur Charact 5:1–12

    Google Scholar 

  • Samanta SK, Kandimalla R, Gogoi B, Dutta KN, Choudhury P, Deb PK, Devi R, Pal BC, Talukdar NC (2018) Phytochemical portfolio and anticancer activity of Murraya koenigii and its primary active component, mahanine. Pharmacol Res 129:227–236

    Article  CAS  PubMed  Google Scholar 

  • Sharma J, Gairola S, Gaur RD, Painuli RM, Siddiqi TO (2013) Ethnomedicinal plants used for treating epilepsy by indigenous communities of sub-Himalayan region of Uttarakhand, India. J Ethnopharmacol 150(1):353–370

    Article  PubMed  Google Scholar 

  • Shreyash N, Bajpai S, Khan MA, Vijay Y, Tiwary SK, Sonker M (2021) Green synthesis of nanoparticles and their biomedical applications: a review. ACS Appl Nano Mater 4(11):11428–11457

    Article  CAS  Google Scholar 

  • Singh S, Ahuja A, Murti Y, Khaliq A (2023) Phyto-pharmacological review on Murraya koenigii (L.) spreng: as an indigenous plant of India with high medicinal potential. Chem Biodiver 20(7):e202300483

    Article  CAS  Google Scholar 

  • Srinivasan D, Nathan S, Suresh T, Lakshmana Perumalsamy P (2001) Antimicrobial activity of certain Indian medicinal plants used in folkloric medicine. J Ethnopharmacol 74(3):217–220

    Article  CAS  PubMed  Google Scholar 

  • Tachibana Y, Kikuzaki H, Lajis NH, Nakatani N (2001) Antioxidative activity of carbazoles from Murraya koenigii leaves. J Agric Food Chem 49(11):5589–5594

    Article  CAS  PubMed  Google Scholar 

  • Tan MA, Sharma N, An SSA (2022) Multi-target approach of Murraya koenigii leaves in treating neurodegenerative diseases. Pharmaceuticals (Basel, Switzerland) 15(2):526

    Google Scholar 

  • Wadanambi PM, Jayathilaka N, Seneviratne KN (2023) A computational study of carbazole alkaloids from Murraya koenigii as potential SARS-CoV-2 main protease inhibitors. Appl Biochem Biotechnol 195(1):573–596

    Article  CAS  PubMed  Google Scholar 

  • Wang H, Shi J, Shi S, Bo R, Zhang X, Hu Y (2022) Bibliometric analysis on the progress of chronic heart failure. Curr Probl Cardiol 47(9):101213

    Article  PubMed  Google Scholar 

  • Wassmuth-Wagner I, Kalinowski HO, Jork H (1995) Isolation and identification of 11-selinen-4alpha,7beta-ol and 10-aromadendranol in the essential oil of Murraya koenigii. Planta Med 61(2):196–197

    Article  CAS  PubMed  Google Scholar 

  • Wilson ML (2022) Topics, author profiles, and collaboration networks in the journal of research on technology in education: a bibliometric analysis of 20 years of research. J Res Technol Educ 5:1–23

    Article  ADS  Google Scholar 

  • Wong SP, Leong LP, William Koh JH (2006) Antioxidant activities of aqueous extracts of selected plants. Food Chem 99(4):775–783

    Article  CAS  Google Scholar 

  • Zahin M, Aqil F, Husain FM, Ahmad I (2013) Antioxidant capacity and antimutagenic potential of Murraya koenigii. Biomed Res Int 2013:263509

    Article  PubMed  PubMed Central  Google Scholar 

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Authors are grateful to the Saudi Digital Library for their generous support in providing full access to their database.


The authors extend their appreciation to the Deputyship for Research&Innovation, Ministry of Education in Saudi Arabia for funding this research work through the project number ISP23-82.

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SIA planned the investigation, evaluated the findings, wrote the article, and oversaw the administrative aspects. MMET gathered the information and revised the text. Both authors have read and approved the manuscript.

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Correspondence to Siddig Ibrahim Abdelwahab.

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Abdelwahab, S.I., Taha, M.M.E. Global research trends of the studies on Murraya koenigii (L.) spreng: a Scopus-based comprehensive bibliometric investigation (1965–2023). Bull Natl Res Cent 47, 138 (2023).

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  • Murraya koenigii
  • Curry tree
  • Knowledge structure and impact
  • International networking
  • Vosviewer
  • R-package