Akinloye OA, Akinloye DI, Onigbinde SB, Metibemu DS (2020) Phytosterols demonstrate selective inhibition of COX-2: In-vivo and in-silico studies of Nicotiana tabacum. Bioorganic Chem 102:104037
Article
CAS
Google Scholar
Alam MN, Bristi NJ, Rafiquzzaman M (2013) Review on in vivo and in vitro methods evaluation of antioxidant activity. Saudi Pharmaceut J 21:143–152
Article
Google Scholar
Amin L (2013) P-glycoprotein inhibition for optimal drug delivery. Drug Target Insights 7:27–34
Article
Google Scholar
Anyasor GN, Okanlawon AA, Ogunbiyi B (2019) Evaluation of anti-inflammatory activity of Justicia secunda Vahl leaf extract using in vitro and in vivo inflammation models. Clin Phytoscience 5:1–13
Article
Google Scholar
Arun KP, Brindha P (2012) Studies on antioxidant and antiarthritic potentials of Jatropha tanjorensis Ellis and Saroja. Int J Pharm Pharm Sci 4:136–138
Google Scholar
Ashafa AOT, Grierson DS, Afolayan AJ (2010) In vitro antioxidant activity of extracts from the leaves of Felicia muricata thunb. An underutilized medicinal plant in the eastern cape province, South Africa. Afr J Tradit Complement Altern Med 7(4):296–302
Attiq A, Jalil J, Husain K, Ahmad W (2018) Raging the war against inflammation with natural products. Front Pharmacol 9:976
Article
Google Scholar
Azeem AK, Dilip C, Prasanth SS, Junise V, Hanan S (2010) Anti-inflammatory activity of the glandular extracts of Thunnus alalunga. Asia Pac J Med 3(10):412–420
Google Scholar
Ballabh P, Braun A, Nedergaard M (2004) The blood–brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol Dis 16:1–13
Article
CAS
Google Scholar
Balogun TA, Iqbal MN, Saibu OA, Akintubosun MO, Lateef OM, Nneka UC, Abdullateef OT, Omoboyowa DA (2021) Discovery of potential HER2 inhibitors from Mangifera indica for the treatment of HER2-Positive breast cancer: an integrated computational approach. J Biomol Struct Dyn. https://doi.org/10.1080/07391102.2021.1975570
Article
PubMed
Google Scholar
Bednar TW, Linsmaier-Bednar EM (1989) Chemical carcinogens in plants and interaction with viruses and cancer causation. In: Kaiser HE (eds) Comparative aspects of tumor development. Cancer growth and progression, vol 5. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1091-1_29
Bouhlali EDT, Alem C, Zegzouti YF (2016) Antioxidant and anti-hemolytic activities of phenolic constituents of six moroccan date fruit (Phoenix dactylifera L.) syrups. Biotechnol Indian J 12(1):45–52
Google Scholar
Chamlagai D, Singh B (2016) Study of in vitro anti-inflammatory activity of ethnomedicinal plants of Sikkim Viscum Articulatum and Acorus Calamus. Asian J Pharm Clin Res 9(3):119–122
CAS
Google Scholar
Chen YZ, Kao SY, Jian HC, Yu YM, Li JY, Wang WH, Tsai CW (2015) Determination of cholesterol and four phytosterols in foods without derivatization by gas chromatography-tandem mass spectrometry. J Food Drug Anal 23(4):636–644
Article
CAS
Google Scholar
Cheng F, Li W, Zhou Y, Shen J, Wu Z, Liu G, Lee PW, Tang Y (2012) admetSAR: a comprehensive source and free tool for evaluating chemical ADMET properties. J Chem Inf Mode 52(11):3099–3105
Article
CAS
Google Scholar
Chou CT (1997) The anti-inflammatory effect of Tripterygium wilfordi Hook on adjuvant induced paw edema in rats and inflammatory mediator’s release. Phytother Res 17:152–154
Article
Google Scholar
Daina A, Michielin O, Zoete V (2017) Swiss ADME: A free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules. Sci Rep 7:42717
Article
ADS
Google Scholar
Erukainure OL, Hafizur RM, Kabir N, Choudhary MI, Atolani O, Banerjee P, Preissner R, Chukwuma CI, Muhammad A, Amonsou EO, Islam MS (2018) Suppressive effects of Clerodendrum volubile P Beauv. [Labiatae] methanolic extract and its fractions on type 2 diabetes and its complications. Front Pharmacol 9:8
Eseyin OA, Sattar MA, Rathore HA, Aigbe F, Afzal S, Ahmed A, Lazhari M, Akthar S (2018) GC-MS and HPLC profiles of phenolic fractions of the leaf of Telfairia occidentalis. Pak J Pharm Sci 31(1):45–50
PubMed
Google Scholar
Friesner RA, Murphy RB, Repasky MP, Frye LL, Greenwood JR, Halgren TA, Sanschagrin PC, Mainz DT (2006) Extra precision glide: Docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes. J Med Chem 49(21):6177–6196. https://doi.org/10.1021/jm051256o
Article
CAS
PubMed
Google Scholar
Govindappa M, Naga SS, Poojashri MN, Sadananda TS, Chandrappa CP (2011) Antimicrobial, antioxidant and in vitro anti-inflammatory activity of ethanol extract and active phytochemical screening of Wedelia trilobata (L.) Hitchc. J Pharmacogn Phytotherapy. 3(3):43–51
Google Scholar
Gunathilake K, Ranaweera K, Rupasinghe H (2018) In vitro anti-inflammatory properties of selected green leafy vegetables. Biomed 6(4):107
CAS
Google Scholar
Hawkins BT, Davis TP (2005) The blood brain barrier/neurovascular unit in health and disease. Pharmacol Rev 57(2):273–185
Article
Google Scholar
Karigidi KO, Akintimehin ES, Omoboyowa DA, Adetuyi FO, Olaiya CO (2020) Effect of Curculigo pilosa supplemented diet on blood sugar, lipid metabolism, hepatic oxidative stress and carbohydrate metabolism enzymes in streptozotocin-induced diabetic rats. J Diabetes Metab Disord. https://doi.org/10.1007/s40200-020-00618-w
Article
PubMed
PubMed Central
Google Scholar
Leelaprakash G, Mohan-Dass S (2011) In vitro anti-inflammatory activity of methanol extract of Enicostemma Axillare. Int J Drug Dev Res 3(3):189–196
Google Scholar
Lipinski CA, Lombardo F, Dominy BW, Feeney PJ (2001) Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv 46:3–26
Article
CAS
Google Scholar
Maestro (2018) Maestro. Schrodinger, LLC.
Nathan C, Ding A (2010) Nonresolving inflammation. Cell 140:871–882
Article
CAS
Google Scholar
Ochulor OC, Njoku OU, Uroko RI, Egba SI (2018) Nutritional composition of Jatropha tanjorensis leaves and effects of its aqueous extract on carbon tetrachloride induced oxidative stress in male Wistar albino rats. Biomed Res 29(19):3569–3576
Google Scholar
Oguntibeju OO (2018) Medicinal plants with anti-inflammatory activities from selected countries and regions of Africa. J Inflamm Res 11:307–331
Article
CAS
Google Scholar
Okereke SC, Arunsi UO, Nosiri CI, Nwadike C (2017) Gas chromatography mass spectrometry/fourier transform infrared (GC-MS/FTIR) spectral analysis of Tithonia diversifolia (Hemsl.) A. Gray leaves. J Med Plants Res 11(19):345–350
Article
Google Scholar
Olayiwola G, Iwalewa EO, Omobuwajo OR, Adebayo AL, Adeniyi AA, Verspohi EJ (2004) The antidiabtes potential of Jathropha tanjorensis leaves. Nig J Nat Prod Med 8:55–58
Google Scholar
Omoboyowa DA, Balogun TA, Omomule OM, Saibu OA (2021) Identification of terpenoids from Abrus precatorius against Parkinson’s disease protein using in silico approach. Bioinfomatics Biology Insight 15:1–8
Google Scholar
Omoregie ES, Osagie AU (2011) Effect of Jatropha tanjorensis leaves supplement on the activities of some antioxidant enzymes, vitamins and lipid peroxidation in rats. J Food Biochem 35(2):409–424
Article
CAS
Google Scholar
Orhue ES, Idu M, Ataman JE, Ebite LE (2008) Hematological and histopathological studies of Jatropha tanjorensis leave in Rabbits. Asian J Biol Sci 1:84–89
Article
Google Scholar
Oyaizu M (1986) Studies of products of browning reaction: antioxidative activity of products of browning reaction prepared from Glucosamine. Jpn J Nutr 44:307–315
Article
CAS
Google Scholar
Parvin S, Das N, Jahan N, Akhter A, Nahar L, Islam E (2015) Evaluation of in vitro anti-inflammatory and antibacterial potential of Crescentia cujete leaves and stem bark. BMC Res Notes 8:412–419
Article
Google Scholar
Prime. (2019). Prime. Schrodinger, LLC.
Rajurkar NS, Hande SM (2011) Estimation of phytochemical content and antioxidant activity of some selected traditional Indian medicinal plants. Indian J Pharm Sci 73(2):146–151
Article
CAS
Google Scholar
Roos K, Wu C, Damm W, Reboul M, Stevenson JM, Lu C, Dahlgren MK, Mondal S, Chen W, Wang L, Abel R, Friesner RA, Harder ED (2019) OPLS3e: extending force field coverage for drug-like small molecules. J Chem Theory Comp 15(3):1863–1874. https://doi.org/10.1021/acs.jctc.8b01026
Article
CAS
Google Scholar
Sangeetha G, Vidhya R (2016) In vitro anti-inflammatory activity of different parts of Pedalium murex (L.). Int J Herb Med 4(3):31–6
Google Scholar
Sastry GM, Adzhigirey M, Day T, Annabhimoju R, Sherman W (2013) Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments. J Computer-Aided Mol Des 27(3):221–234. https://doi.org/10.1007/s10822-013-9644-8
Article
ADS
CAS
Google Scholar
Scheler S, Fahr A, Liu X (2015) Linear combination methods for prediction of drug skin permeation. ADMET & DMPK 2(4) 199–220
Tirona RG, Kim RB (2017) Introduction to clinical pharmacology In: Clinical and translational science (2nd Edn): Academic press. USA, pp 365–388
Turner JV, Agatonovic-kustrin S (2007) In silico prediction of oral bioavailability. In: comprehensive medicinal chemistry II. 5: 699–724
Wang E, Sun H, Wang J, Wang Z, Liu H, Zhang JZH, Hou T (2019) End-point binding free energy calculation with MM/PBSA and MM/GBSA: Strategies and application in drug design. Chem Rev 119:9478–9508
Article
CAS
Google Scholar
Williams CS, Mann M, Dubois RN (1999) The role of cyclooxygenases in inflammation, cancer, and development. Oncogene 18(55):7908–7916
Article
CAS
Google Scholar
Yesmin S, Paul A, Naz T, Rahman A, Akhter SF, Wahed MI, Emran TB, Siddiqui SA (2020) Membrane stabilization as a mechanism of the anti-inflammatory activity of ethanolic root extract of Choi (Piper chaba). Clin Phytoscience 6:1–10
Article
Google Scholar
Zhou S (2008) Drugs behave as substrates, inhibitors and inducers of human cytochrome P450 3A4. Curr Drug Metab 9:310
Article
CAS
Google Scholar