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  1. Distinguishing between a pituitary adenoma and a pituicytoma can be challenging. Hormonal changes in pituicytomas are uncommon, and the tumor's mass effect has triggered most symptoms. There were only two repo...

    Authors: Magdelene Amoateng, Eiman Ibrahim, Yasir Ahmad, Anoush Calikyan and Ilja Hulinsky
    Citation: Bulletin of the National Research Centre 2022 46:218
  2. Diabetes, a cardiometabolic condition with social and health ramifications, is already a global epidemic. Diabetes affects 422 million people worldwide, with the majority living in middle- and low-income count...

    Authors: Ezekiel A. Olugbogi, Damilola S. Bodun, Shola D. Omoseeye, Anita O. Onoriode, Favour O. Oluwamoroti, Joshua F. Adedara, Isaac A. Oriyomi, Fatimat O. Bello, Favour O. Olowoyeye, Oluwatomilola G. Laoye, Damilola B. Adebowale, Aanuoluwapo D. Adebisi and Olaposi I. Omotuyi
    Citation: Bulletin of the National Research Centre 2022 46:217
  3. The commercial cultured milk drinks contain either single or mixed probiotic species and supply in different serving sizes. It is known that different combinations of probiotics might provide the various produ...

    Authors: Yun Khoon Liew, Kyan Aung, Li Li Chan, Sandhya Baskaran and Siew Thong Mak
    Citation: Bulletin of the National Research Centre 2022 46:216
  4. The increase in the demand for synthetic drugs due to the surge in the cases of drug-resistant infectious organisms has led to the search for new medicines in plants. Some plants have phytochemicals that can serv...

    Authors: O. M. Oyawoye, T. M. Olotu, S. C. Nzekwe, J. A. Idowu, T. A. Abdullahi, S. O. Babatunde, I. A. Ridwan, Gaber E. Batiha, Nike Idowu, Mohammed Alorabi and Hani Faidah
    Citation: Bulletin of the National Research Centre 2022 46:214
  5. Leptin exerts both protective and deleterious effects on the heart; the first occurs under hypoxia- or ischemia-associated damage, the second is a pro-hypertrophic factor on cardiomyocytes. Therefore, leptin c...

    Authors: Wendy Natalia Rosado Loman, Jarumi Hishel Cruz Hernández, Nancy Patricia Gómez-Crisóstomo, Erick N. de la Cruz-Hernández, Carlos Francisco Aguilar-Gamas and Eduardo Martínez-Abundis
    Citation: Bulletin of the National Research Centre 2022 46:213
  6. The development of barotrauma in COVID-19 patients who were ventilated and admitted to the intensive treatment unit seemed to have been a problematic issue in the COVID era. This study aimed to explore the pos...

    Authors: Roopak Dubey, Kamal Kumar Sen and Aparajita Mishra
    Citation: Bulletin of the National Research Centre 2022 46:212
  7. Abnormal thyroid hormone levels have been reported in type 2, but the relationship between thyroid hormone levels and glycaemic indices: fasting plasma glucose (FPG), C-peptide (C-pep) and glycated haemoglobin...

    Authors: Idongesit Kokoabasi Isong, Christopher E. J. Udiong and Uwem Okon Akpan
    Citation: Bulletin of the National Research Centre 2022 46:211
  8. In 2003, the first case of severe acute respiratory syndrome coronavirus (SARS-CoV) was recorded. Coronaviruses (CoVs) have caused a major outbreak of human fatal pneumonia. Currently, there is no specific dru...

    Authors: David Ebuka Arthur, Benjamin Osebi Elegbe, Augustina Oyibo Aroh and Mahmoud Soliman
    Citation: Bulletin of the National Research Centre 2022 46:210
  9. Approximately 69% of population in Tanzania lacks better sanitation, while 45.6% lacks access to clean and safe water. To leverage this shortage, several technologies have been used for purifying water from va...

    Authors: Faraja Evod Komba, Christina Fabian, Elianaso Elimbinzi and Godlisten N. Shao
    Citation: Bulletin of the National Research Centre 2022 46:208
  10. The aim of this study is to evaluate an experimental tricalcium silicate phase (C3S) and tetracalcium phosphate (TTCP) material to be used as a root canal furcation perforation repair. C3S and TTCP phases were sy...

    Authors: M. M. Radwan and M. E. Khallaf
    Citation: Bulletin of the National Research Centre 2022 46:207
  11. Coconut water is a relished beverage traditionally used as a remedy for childhood diarrhoea and gastroenteritis. It can be given to an individual who has hangover or suspected to have ingested a toxic substanc...

    Authors: Okezie Emmanuel, Ifeanyichukwu Elekwa, Chidiebere Paul-Joseph, Victor C. Ude, Ozioma G. Egedeuzu, Solomon N. Ijioma, Victor Obioma Amachaghi, Chikezie Uche-Ikonne and Eziuche A. Ugbogu
    Citation: Bulletin of the National Research Centre 2022 46:206
  12. Preparation of Ipomoea asarifolia (Desr.) (Convolvulaceae) is widely used in traditional African medicine for the treatment of different kinds of ailments such as syphilis, malaria, convulsions and rheumatism.

    Authors: Samaila S. Chiroma, Abdullahi Balarabe Nazifi, Jamilu Ya’u, Musa Aliyu, Lawal A. Bichi and Samaila M. Chiroma
    Citation: Bulletin of the National Research Centre 2022 46:205
  13. High-fat diet (HFD) has been linked to oxidative stress, dyslipidaemia, obesity and cardiovascular diseases. Studies have shown that medicinal plants have antioxidant properties and may have protective effects...

    Authors: Osebhahiemen Ibukun and Ehimwenma S. Omoregie
    Citation: Bulletin of the National Research Centre 2022 46:204
  14. This study aimed to evaluate the relationship between cardiac troponin I and T (cTnI, cTnT) and creatine kinase (CK)-MB during the acute phase of Kawasaki disease (KD) and the development of coronary artery in...

    Authors: Mahdieh Mousavi Torshizi, Seyed-Reza Raeeskarami, Fatemeh Tahghighi, Elaheh Malakan-Rad, Mohammad-Hassan Moradinejad, Yahya Aghighi and Vahid Ziaee
    Citation: Bulletin of the National Research Centre 2022 46:203
  15. Cyclodextrins offer a range of biomedical applications in the pharmaceutical and biotechnology industries. Cyclodextrins (CDs) are oligosaccharides composed of glucose as repeating units (6–9 repeating units g...

    Authors: Jatinder Singh, Isha Dhamija, Harmanpreet Meehenian, Neeraj Kumar, Simran Simran, Muskan Muskan, Madan L. Verma and Sandeep Kumar
    Citation: Bulletin of the National Research Centre 2022 46:202
  16. Growth and development of the dental arch is considered a continuous and complex biological process. During transition from primary to mixed then to permanent dentition, dental arch form, length and width vary...

    Authors: Rasha F. Sharaf, Ehab Radwan, Ghada A. Salem and Mohamed Abou El-yazeed
    Citation: Bulletin of the National Research Centre 2022 46:201
  17. This study evaluated the heavy metal identity and content of registered Thai Traditional medicine (TTM) preparations in Thailand to ensure consumer safety.

    Authors: Sornkanok Vimolmangkang, Dolly Rani, Naruemon Prestwong, Chayanis Sutcharitchan and Duangkamol Pakdeesattayapong
    Citation: Bulletin of the National Research Centre 2022 46:200
  18. Preharvest and postharvest conditions of medicinal plants strongly affect the quantity and quality of their secondary metabolites. Here, the effect of different harvesting times (5 am, 12 noon and 5 pm) and di...

    Authors: Seyedeh Fatemeh Khademi Doozakhdarreh, Jalal Khorshidi and Mohammad Reza Morshedloo
    Citation: Bulletin of the National Research Centre 2022 46:199
  19. Saudi Arabia is one of the countries seriously affected by coronavirus disease 2019 (COVID-19) worldwide. With a few cases in early March, the daily spread of this disease increased to nearly 5000 at one point...

    Authors: Asharaf Abdul Salam, Rshood M. Al-Khraif, Thandassery R. Dilip and Ibrahim Elsegaey
    Citation: Bulletin of the National Research Centre 2022 46:198
  20. Alcohol intake, particularly to cope up with stress and depression experienced by commercial drivers during the peak of the COVID-19 pandemic, is alarming as a rise in sales has been reported in certain countr...

    Authors: Great Iruoghene Edo and Laurine Chikodiri Nwosu
    Citation: Bulletin of the National Research Centre 2022 46:197
  21. Tacca flour obtained from tacca tubers, an underutilized crop rich in carbohydrate and phytochemicals, was subjected to physical, chemical and enzymatic modifications which were supplemented into wheat flour f...

    Authors: Emmanuel Omotayo Ojewumi, Olufunmilayo Sade Omoba and Olugbenga Olufemi Awolu
    Citation: Bulletin of the National Research Centre 2022 46:196
  22. Treating cancer is challenging for both the patient and the physician. This may be explained by the fact that treatment regimens rely on either chemotherapy alone or a combination with radiotherapy. Both modal...

    Authors: Marwa Mohamed Ellithy, Riham Mohamed Aly and Heba El-Sayed Tarek
    Citation: Bulletin of the National Research Centre 2022 46:195
  23. On the staggering emergence of the Omicron variant, numerous questions arose about the evolution of virulence and transmissibility in microbes.

    Authors: Antoine AbdelMassih, Abrar Sedky, Ahmed Shalaby, AlAmira-Fawzia Shalaby, Alia Yasser, Aya Mohyeldin, Basma Amin, Basma Saleheen, Dina Osman, Elaria Samuel, Emmy Abdelfatah, Eveen Albustami, Farida ElGhamry, Habiba Khaled, Hana Amr, Hanya Gaber…
    Citation: Bulletin of the National Research Centre 2022 46:194
  24. Two plant essential oils, basil (Ocimum basilicum L.) and petitgrain mandarin (Citrus reticulate L.), and one pyrethroid chemical insecticide, lambda-cyhalothrin, were evaluated against two of the most important ...

    Authors: Raafat Badr Abo Arab, Nariman Mohamed El-Tawelah, Ahmed Mohamed Abouelatta and Amal Moustafa Hamza
    Citation: Bulletin of the National Research Centre 2022 46:192
  25. A variety of accessible data, including those of single-nucleotide polymorphisms (SNPs) on the human p53 gene, are made widely available on a global scale. Owing to this, our investigation aimed to deal with t...

    Authors: Saruar Alam, Mohammad Sayem, Martiniano Bello, Sadia Islam Mou, Nairita Ahsan Faruqui, Faruk Hossain and Md. Kamrul Hasan
    Citation: Bulletin of the National Research Centre 2022 46:191
  26. Packaging of locust beans is done to prevent deterioration and promote its shelf-life. This research was carried out to develop and evaluate a cocoyam starch-banana peels nanocomposite film for locust beans pa...

    Authors: Adeshina Fadeyibi, Kehinde Peter Alabi, Mary Fadeyibi and Adewale Oluwaseun Adewara
    Citation: Bulletin of the National Research Centre 2022 46:190
  27. Leishmaniasis is one of the neglected tropical diseases which is prevalent in the tropical regions of the world most especially in Africa. It is caused by the Leishmania species and transmitted to humans majorly ...

    Authors: Fabian Audu Ugbe, Gideon Adamu Shallangwa, Adamu Uzairu and Ibrahim Abdulkadir
    Citation: Bulletin of the National Research Centre 2022 46:189
  28. The current study was conducted to find out an eco-friendly and cost-efficient way to prepare copper nanoparticles (CuNPs) by utilizing Grewia asiatica L. leaf extract, which was found to be a very effective anti...

    Authors: Arifa Tahir, Cristina Quispe, Jesús Herrera-Bravo, Hafsa Iqbal, Zia ul Haq, Faiza Anum, Zeeshan Javed, Anam Sehar and Javad Sharifi-Rad
    Citation: Bulletin of the National Research Centre 2022 46:188
  29. This study estimates the migration and levels of phthalate esters in drinking water and fruit drinks packed in plastics and tetra pak cartons that are regularly available for consumption in Nigeria. The probab...

    Authors: Abiodun Odunlami Adegunwa, Aderibigbe Kola Adegunwa and Rokeebat Motunrayo Oyatoyinbo
    Citation: Bulletin of the National Research Centre 2022 46:187
  30. Optimization of adsorption processes using statistical methods of experiment for the removal of pollutants from wastewater, in an effort to curb the global problem of water pollution, is increasingly being ado...

    Authors: Zaharaddeen Nasiru Garba, Patricia Adamma Ekwumemgbo and Godwill Stephen
    Citation: Bulletin of the National Research Centre 2022 46:186
  31. Vineyards are a crop of great economic importance in Portugal, whose production of over 224 kha of vines may be affected by evolving global changes, as new pests arrive in greater numbers at more northern lati...

    Authors: Maria da Conceição Proença and Maria Teresa Rebelo
    Citation: Bulletin of the National Research Centre 2022 46:185
  32. This study evaluated the durability of optical properties of chameleon effect of Omnichroma and Essentia composite thermocycled in black dark drinks. 180 specimens of 10 mm diameter × 2 mm thickness from each ...

    Authors: Bassma Abdelhamed, Asmaa Abdel-Hakeem Metwally and Heba A. Shalaby
    Citation: Bulletin of the National Research Centre 2022 46:184
  33. β-catenin is an important unit of the Wnt/β-catenin signaling pathway, a conserved process involving several physiological activities, encompassing differentiation and cell proliferation, etc. The dysfunction ...

    Authors: Ayomide Oluwadarasimi Adebesin, Abigail Oluwakemi Ayodele, Olabode Omotoso, Precious Ayorinde Akinnusi and Samuel Olawale Olubode
    Citation: Bulletin of the National Research Centre 2022 46:183
  34. Indiscriminate disposal of polyethylene materials has become a regular practice among developing nations of Africa, especially in Nigeria. This has resulted in environmental pollution; hence, this study invest...

    Authors: Temitope Oluwatosin Ayeni, Daniel Juwon Arotupin and Oisagah Ezekiel Ayo
    Citation: Bulletin of the National Research Centre 2022 46:182
  35. Honey is consumed for the derived benefits as sweetener, for healing wounds, skin burns, regulating blood sugar level, treatments of some ailments, etc. In Nigeria, adulteration of honey is a serious concern, ...

    Authors: Kayode Lawrence Akinwande and Ajayi Joshua Oladapo
    Citation: Bulletin of the National Research Centre 2022 46:181
  36. The aim of this work was to study the influence of simulated body fluid (SBF) and Pseudomonas aeruginosa (in Mueller Hinton Broth, MHB media) on the hydration reactions, formation of strätlingite (C2ASH8) and mor...

    Authors: M. M. Radwan and Shaymaa M. Nagi
    Citation: Bulletin of the National Research Centre 2022 46:180
  37. Early detection of delirium through systematic screening is essential to mitigate and prevent possible consequences. The 4 'A's Test (4AT) is a new tool that can be used for delirium detection easily and witho...

    Authors: Olga Muser, Kevin Seiler, Stefanie Bachnick, Beatrice Gehri, Franziska Zúñiga and Wolfgang Hasemann
    Citation: Bulletin of the National Research Centre 2022 46:179
  38. Polypharmacy and potentially inappropriate medications (PIMs) could cause adverse drug events leading to poor health outcomes. This burden is addressed through deprescribing practice. However, data on deprescr...

    Authors: Safiya Bala Borodo, Abubakar Ibrahim Jatau, Mustapha Mohammed, Nafiu Aminu, Zayyanu Shitu and Abubakar Sha’aban
    Citation: Bulletin of the National Research Centre 2022 46:178
  39. In spite of the significant escalation in the depth of our conception and regulation of breast cancer over the past decades, the malady is still a serious community health challenge globally and poses a substa...

    Authors: Sagiru Hamza Abdullahi, Adamu Uzairu, Gideon Adamu Shallangwa, Sani Uba and Abdullahi Bello Umar
    Citation: Bulletin of the National Research Centre 2022 46:177
  40. The unpredicted pandemic disease COVID-19 first flared up adversely in Europe by imparting interminable force of infected and fatality cases to Italy. In late February 2020, the novel severe acute respiratory ...

    Authors: Asma Akter Bhuiyan, Sreyashi Brahmachari, Israt Jahan Ripa and Rashed Noor
    Citation: Bulletin of the National Research Centre 2022 46:176
  41. Microorganisms' survival is based on the importance of growth factors found in the microbial environment, as well as their overwhelming appetite for survival which is controlled by their genetic material. This...

    Authors: Omololu Daniel Oladapo, Anthony Kayode Onifade and Michael Tosin Bayode
    Citation: Bulletin of the National Research Centre 2022 46:175
  42. Coumarin and fatty alcohol are abundant in nature, particularly in plants, and have been reported to have therapeutic uses. Strychnos innocua (Loganiaceae family) is commonly utilized for medicinal purposes in se...

    Authors: Ahmed Jibrin Uttu, Muhammad Sani Sallau, Ogunkemi Risikat Agbeke Iyun and Hamisu Ibrahim
    Citation: Bulletin of the National Research Centre 2022 46:174
  43. The purpose of this research was to compare the effect of shape factors of biconvex compacts on prediction of dilution potential from polynomial regression models of area ratio-mass fraction data of novel α-la...

    Authors: Ilyasu Salim, Adeniji Kehinde Olowosulu and Abdulrahman Abdulsamad
    Citation: Bulletin of the National Research Centre 2022 46:173
  44. The aim of this Systematic review is to provide more accurate knowledge about the relation between bruxism, Dental implant and the implant-supported prosthesis.

    Authors: Abboud Youssef, Joe Hobeiche, Amine El Zoghbi, Rola Mortada and Ziad Salameh
    Citation: Bulletin of the National Research Centre 2022 46:172
  45. Synthetic insecticides employed in seed treatment are often phytotoxic, especially at slightest misapplications. Cowpea seed is mainly attacked by Callosobruchus maculatus. It is established that azadirachtin, my...

    Authors: Ewa Ogbonnaya, Ansari Ahmad Rizwan, Emakoji Ile Bamidele and Victoria Ayuba
    Citation: Bulletin of the National Research Centre 2022 46:171

    The Correction to this article has been published in Bulletin of the National Research Centre 2022 46:193

  46. The emerging viral pandemic worldwide is associated with a novel coronavirus, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). This virus is said to emerge from its epidemic center in Wuhan, China...

    Authors: Deepak Agarwal, Imran Zafar, Syed Umair Ahmad, Sujit Kumar, Qurat ul Ain, Jitendra Kumar Sundaray and Mohd Ashraf Rather
    Citation: Bulletin of the National Research Centre 2022 46:170
  47. Bryonia alba extract is a well-known drug which is being utilized as phytomedicines and homoeopathic preparations since more than two centuries. This medicine is frequently used in clinical practice for flu-like ...

    Authors: Pritam Goswami, Debasmita Chatterjee, Sayak Ghosh, Krishnendu Paira and Satadal Das
    Citation: Bulletin of the National Research Centre 2022 46:169

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