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Lymphatic filariasis (LF), often referred to as elephantiasis, has been identified as one of the 17 neglected tropical diseases by the World Health Organization. Currently, there are no vaccines available to t...
Monoamine oxidase (MAO) is an enzyme that has been targeted pharmacologically for the treatment of depression and neurodegenerative diseases such as Parkinson's disease. To avoid side effects, drugs currently ...
Since the outbreak of coronavirus (COVID-19) disease was reported in 2019, huge human and material resources have been expended globally to combat the spread of the disease. Achieving herd immunity through mas...
The original article was published in Bulletin of the National Research Centre 2023 47:37
Hepatitis B virus (HBV) infection continues to be a global public health problem. As of 2019, there were 296 million people chronically infected with HBV, resulting in nearly 1 million deaths from decompensate...
Anti-glomerular basement membrane (GBM) disease and ANCA-associated vasculitis (AAV) diseases are rare. It is associated with variable renal manifestations and increased mortality, thus requiring early aggress...
Juvenile psammomatoid ossifying fibroma is a rare variant of conventional ossifying fibroma that affects the maxillofacial complex in children and adolescents. It is a benign fibro-osseous neoplasm with aggres...
Neuraxial anesthesia is widely used for labor analgesia in the USA, such as epidural, combined spinal–epidural, and dural puncture epidural (DPE). Post-dural puncture headache (PDPH) is a well-known complicati...
Origanum majorana (O. majorana) is one of the most widely used herbs in Egypt due to its antioxidant, anti-inflammatory, anti-genotoxic, antimutagenic, anticoagulant and beneficial properties. Our study's main go...
Despite the ongoing onchocerciasis control program that has been in place in Mahenge for more than two decades using the Community Directed Treatment with Ivermectin (CDTI) strategy, the persistent transmissio...
Our present study aimed to evaluate the effect of calcium phosphate nanoparticles in chlorohexidine paste on the odontogenic differentiation of human dental pulp stem cells. The human dental pulp stem cells (H...
The Correction to this article has been published in Bulletin of the National Research Centre 2023 47:44
The incidence of mild postoperative complications has been shown to be strongly associated with the beneficial effects provided through minimally invasive surgery. The main objective of the present study was t...
Previous discussions regarding variant femoral nerves often report an aberrant slip of a small portion of the iliacus muscle as a common cause of the femoral nerve splitting. Within these reported cases, the v...
Andrographis paniculata (Burm. f.) Wall. ex Nees. is an important medicinal plant grown in tropical and sub-tropical regions where semi-arid condition restricts economically viable cultivation. Foliar exogenous a...
When health systems worldwide grapple with the coronavirus disease 2019 (COVID-19) pandemic, its effect on the global environment is also a significant consideration factor. It is a two-way process where the p...
Foot and Mouth disease (FMD) is an acute contagious and highly infectious disease of domesticated and wild cloven-hoofed animals characterized by the appearance of vesicular lesions at the epithelium of the mo...
The demand for designing a new technology that can emphasize the complete removal of heavy metals increased as a result of the industrial revolution. Bioremediation was found to have a potent impact on the deg...
Blinatumomab could be successfully used to reduce minimal residual disease (MRD) prior to hematopoietic stem cell transplantation (HSCT) in pediatric B cell precursor acute lymphoblastic leukemia (BCP-ALL), bu...
Inflammasomes are intracellular multiprotein complexes that sense danger signals from damaged cells and pathogens and assemble to mediate caspase-1 activation, which results in the proteolytic cleavage of pro-...
SARS-CoV-2 is the causative agent of worldwide pandemic disease coronavirus disease 19. SARS-CoV-2 bears positive sense RNA genome that has organized and complex pattern of replication/transcription process in...
Unprovoked spontaneous uterine rupture in a primigravid unscarred uterus is a rare but serious obstetric complication. Our case highlights a prelabour uterine rupture in a primiparous patient with an anterior ...
The original article was published in Bulletin of the National Research Centre 2023 47:16
Objective of this work was to investigate the impact of isolated honeybee-specific-lactic acid bacteria (Hbs-LAB) that isolated from worker's bee intestinal tracts on bee health as well as bee colony activity ...
Heart Study has been operating for more than 40 years, and throughout that time it has found a number of risk variables that interact negatively to have an overall negative effect on cardiovascular disease (CV...
Previous studies have shown significant differences and lack clarity on whether resistance to either isoniazid or rifampicin can predict multidrug resistance tuberculosis (MDR-TB). Some consider rifampicin res...
Manganese (Mn) and Selenium (Se) deficiencies are noted in adult patients with chronic kidney disease (CKD). However, levels of these trace elements have not been well studied in the paediatric CKD population....
Persistent pain after total hip arthroplasty (THA) is a real concern for the surgeon and is a significant cause of patient dissatisfaction; periprosthetic joint infection (PJI), aseptic loosening, and instabil...
Caffeine intake has been positively or negatively associated with the risk of chronic disease. Genome-wide association studies identified single-nucleotide polymorphisms (rs2472297 and rs2470893) in Cytochrome...
In the current global scenario, the monkeypox virus has infected over 3000 individuals from endemic countries like Nigeria, along with non-endemic countries like the UK, Canada, the USA, etc. Based on the curr...
Amyloid beta peptide (Aβ) is the main component of plaques and is known to play a role in the development of Alzheimer's disease (AD). As a result, structures that can trap Aβ or disrupt the interaction betwee...
Malaria rapid diagnostic tests (mRDTs) have played an important role in the early detection of clinical malaria in an endemic area. While several mRDTs are currently on the market, the availability of mRDTs wi...
Primary hypertriglyceridemia (HTG) is a very rare autosomal recessive disorder caused by the mutations of the genes related with triglyceride metabolism, including apolipoproteins and lipoprotein lipase (LPL) ...
The Correction to this article has been published in Bulletin of the National Research Centre 2023 47:26
Acinetobacter baumannii is recognized as a major threat that causes healthcare-associated infections and causes a huge challenge to the health system worldwide. This research study was designed to detect the type...
Pulmonary rehabilitation (PR) has proven to improve the physical and psychosocial function in patients with chronic obstructive pulmonary disease (COPD). However, the gains achieved during pulmonary rehabilita...
Antimicrobial resistance is a global problem and involve pathogens which have the potential to move between food producing animals and humans by direct exposure or through the food chain or the environment. Th...
Selective androgen receptor modulators (SARMs) are becoming increasingly common amongst athletes and the general population, but their side effect profile in human subjects at recreational doses is understudied.
The recent outbreaks of Marburg virus disease (MVD) in Guinea and Ghana have become a major public health concern not only to the West African sub-region but a threat to global health.
Polymelia is an occasional and congenital malformation in bovine calves, characterized by the presence of single or multiple accessory limb(s) at various body regions, which are often called the supernumerary ...
Implants immediately loaded full-arch prosthesis in maxilla is always a challenge, especially when the zone 2 is extremely defected. To achieve a satisfying result, different therapeutic alternatives have been...
Nanomaterials have emerged as a fascinating class of materials in high demand for a variety of practical applications. They are classified based on their composition, dimensions, or morphology. For the synthes...
Typhoid fever, a disease caused by a gram negative bacterial species known as Salmonella typhi, constitutes a significant cause of morbidity and mortality, especially in developing nations of the world. Antibioti...
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic has been leading to dramatic health, social and economic problems around the world. It was necessary to introduce worldwide vaccination...
Egyptian water buffalo as a dairy animal is adapted to the environmental conditions in Egypt and most of it is with small farmers, therefore, it was necessary to pay attention to improve its nutrition, increas...
The stay-at-home conditions due to the COVID-19 pandemic significantly alter the Malaysian lifestyle, and all Malaysians faced difficulties adopting the new lifestyle. A hypothetico-deductive technique has bee...
Dental caries is the most prevalent oral infection affecting the individuals worldwide, and Streptococcus mutans is the major microorganism involved in its pathology. Thus, the aim was to evaluate the antibact...
The Correction to this article has been published in Bulletin of the National Research Centre 2023 47:159
One of the major threats to human health is malignancy. Treatment regimens usually followed by either chemo or radiotherapy have a wide range of collateral unwanted side effects. Scientists seek alternatives w...
Paracoccidioidomycosis is a systemic fungal infection that is potentially fatal, and the most prevalent of its kind in Latin America. The predisposition to infection appears to be related to abnormalities in c...
Mucopolysaccharidoses IVA is an autosomal recessive lysosomal storage disease resulting in skeletal and cartilage dysplasia. Hematopoietic stem cell transplantation is a good therapeutic option for MPS IV. Her...
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