Changes in tryptophan and phenylalanine in chronic HCV patients treated with direct acting antiviral (sofosbuvir)

Bulletin of the National Research Centre

Table 3 Amino acids levels according to severity of depression among the treated group

Variable	Mild/moderate (n = 4)			Severe (n = 4)			Very severe (n = 32)			KW test	p
Variable	Mean	± SD	Range	Mean	± SD	Range	Mean	± SD	Range	KW test	p
Tryptophan (μg/ml)	9.34	3.77	3.79–12.2	8.87	0.80	7.89–9.6	6.57	2.20	3.42–11.58	7.32	0.026 (S)
Phenylalanine (ng/ml)	2.09	0.02	2.07–2.13	2.34	0.17	2.12–2.55	2.52	0.28	2.11–2.99	11.4	0.003 (S)