Table 1 Table of included studies, detailing title, author’s name, publication year, country of origin, methodology and design, duration of activity, quality assessment, patient population in each arm of the comparison, and baseline differences between populations
Title | Author | Type | Design | Population | Duration | Quality | Baseline |
|---|---|---|---|---|---|---|---|
Frequency of hypoglycemia after different bariatric surgical procedures | Brix et al. (2019) (Austria) | Single center without patient matching | OGTT, Q, MMTT no DM2 pts included | Nexp = 175 Nctrl = 62 (Total: 237) | 729 days (1/1/2017–31/12/2018) | NOS: 5 ROBINS-I: Serious | RYGB: higher BMI |
Incidence of hypoglycemia after gastric bypass vs. sleeve gastrectomy: A randomized trial | Capristo et al. (2018) (Italy) | Single center with patient matching | CGM, OGTT, MMTT, Q no DM2 pts included | Nexp = 59 Nctrl = 58 (Total: 117) | 760 days (1/12/2012–31/12/2014) | NOS: 9 ROBINS-I: Low | No baseline differences |
Symptomatic and asymptomatic hypoglycemia after three different bariatric procedures: A common and severe complication | Lazar et al. (2019) (Israel) | Single center without patient matching | MMTT, Q, CGM no DM2 pts included | Nexp = 16 Nctrl = 15 (Total: 31) | 364 days (1/8/2017–31/7/2018) | NOS: 5 ROBINS-I: Serious | RYGB: pts with more education years |
Prevalence of and risk factors for hypoglycemic symptoms after gastric bypass and sleeve gastrectomy | Lee et al. (2015) (USA) | Single center without patient matching | Q DM2 pts included | Nexp = 355 Nctrl = 95 (Total: 450) | 1491 days (1/8/2008–31/8/2012) | NOS: 4 ROBINS-I: Critical | RYGB: 78.9% of pts |
Comparison of hormonal response to a mixed-meal challenge in hypoglycemia after sleeve gastrectomy vs. gastric bypass | Lee et al. (2022) (USA) | Single center without patient matching | MMTT no DM2 pts included | Nexp = 20 Nctrl = 23 (Total: 43) | 2190 days (1/1/2009–31/12/2014) | NOS: 6 ROBINS-I: Serious | RYGB: older pts, less time since surgery |
Continuous glucose monitoring in subjects undergoing bariatric surgery: Diurnal and nocturnal glycemic patterns | Lupoli et al. (2020) (Italy) | Single center without patient matching | CGM DM2 pts included | Nexp = 22 Nctrl = 29 (Total: 51) | 364 days (1/1/2019–31/12/2019) | NOS: 5 ROBINS-I: Serious | No baseline differences |
Risk factors for spontaneously self-reported postprandial hypoglycemia after bariatric surgery | Nannipieri et al. (2016) (Italy) | Single center without patient matching | OGTT, Q no DM2 pts included | Nexp = 34 Nctrl = 51 (Total: 85) | 729 days (1/1/2013–31/12/2014) | NOS: 6 ROBINS-I: Moderate | LSG: older pts, more obese pts |
Glycemic variability and hypoglycemia before and after Roux-en-Y gastric bypass and sleeve gastrectomy: A cohort study of females without diabetes | Nilsen et al. (2023) (Sweden) | Single center without patient matching | CGM, Q no DM2 pts included | Nexp = 28 Nctrl = 19 (Total: 47) | 364 days (1/1/2022–31/12/2022) | NOS: 6 ROBINS-I: Moderate | Female pts RYGB: higher BMI |
Clinical features of symptomatic hypoglycemia observed after bariatric surgery | Nor Hanipah et al. (2018) (USA) | Single center without patient matching | OGTT, MMTT DM2 pts included | Nexp = 104 Nctrl = 13 (Total: 117) | 5112 days (1/1/2002–31/12/2015) | NOS: 4 ROBINS-I: Critical | No baseline differences |
Persistent post-bariatric surgery hypoglycemia: A long-term follow-up reassessment | Ostrovsky et al. (2023) (Israel) | Single center without patient matching | CGM, MMTT, Q no DM2 pts included | Nexp = 10 Nctrl = 5 (Total: 15) | 333 days (1/6/2020–30/4/2021) | NOS: 5 ROBINS-I: Serious | LSG: older pts RYGB: greater weight regains |
Comparison between RYGB, DS, and VSG effect on glucose homeostasis | Roslin et al. (2012) (USA) | Single center without patient matching | OGTT, HOMA-IR DM2 pts included | Nexp = 12 Nctrl = 13 (Total: 25) | 365 days (1/1/2012–31/12/2012) | NOS: 6 ROBINS-I: Moderate | No baseline differences |
Response to glucose tolerance testing and solid high carbohydrate challenge: Comparison between Roux-en-Y gastric bypass, vertical sleeve gastrectomy, and duodenal switch | Roslin et al. (2014) (USA) | Single center without patient matching | OGTT DM2 pts included | Nexp = 13 Nctrl = 12 (Total: 25) | 364 days (1/1/2013–31/12/2013) | NOS: 6 ROBINS-I: Moderate | No baseline differences |
Hypoglycemia during oral glucose tolerance test among post-bariatric surgery pregnant patients: Incidence and perinatal significance | Rottenstreich et al. (2018) (Israel) | Single center without patient matching | OGTT no DM2 pts included | Nexp = 30 Nctrl = 55 (Total: 85) | 4017 days (1/1/2006–31/12/2016) | NOS: 6 ROBINS-I: Moderate | Pregnant pts No baseline differences |
Effect of single anastomosis duodenal-ileal bypass with sleeve gastrectomy on glucose tolerance test: Comparison with other bariatric procedures | Sessa et al. 2019 (Sessa et al. 2019) | Single center with patient matching | OGTT no DM2 pts included | Nexp = 11 Nctrl = 7 (Total: 18) | 637 days (1/6/2016–28/2/2018) | NOS: 6 ROBINS-I: Moderate | No baseline differences |
Weight regain in patients with symptoms of post-bariatric surgery hypoglycemia | Varma et al. (2017) (USA) | Single center without patient matching | Q DM2 pts included | Nexp = 334 Nctrl = 94 (Total: 428) | 272 days (1/8/2013–30/4/2014) | NOS: 4 ROBINS-I: Critical | RYGB: 78% of pts |
Continuous glucose monitoring in bariatric patients undergoing laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass | Wysocki et al. (2019) (Poland) | Single center without patient matching | CGM DM2 pts included | Nexp = 14 Nctrl = 18 (Total: 32) | 364 days (1/1/2018–31/12/2018) | NOS: 5 ROBINS-I: Serious | RYGB: more pts with DM2, higher proportion of females DM2: higher ASA score, older pts |