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Bulletin of the National Research Centre
Fig. 2 | Bulletin of the National Research Centre

Fig. 2

From: Astrocytes’ innate role in neurodegenerative disorders

Fig. 2

In a situation with high levels of reactive oxygen species (ROS), the transcription factor Nrf2 is released from binding to the protein Keap1, transported to the nucleus, and then binds to ARE gene sequences which allow for the activation of antioxidant genes such as HO-1 and NQO1. Image created in BioRender.com.

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