Fig. 6From: A detailed review of pathophysiology, epidemiology, cellular and molecular pathways involved in the development and prognosis of Parkinson's disease with insights into screening modelsRadical species development. ROS are produced by a variety of metabolic processes, including oxidative phosphorylation, superoxide anion (O2 •), Singlet oxygen (O2), hydrogen peroxide (H2O2), hydroxyl radical (OH•) nitric oxide (NO•) and mitochondrial-derived reactive oxygen species (mtROS), hydroxyl ion (OH-) (Trist et al. 2019)Back to article page