Bulletin of the National Research Centre

Table 1 Docking molecular score of chalcone derivatives with MAO-A and MAO-B enzymes

From: Design of new reversible and selective inhibitors of monoamine oxidase A and a comparison with drugs already approved

Ligand	MAO-A	MAO-B	Difference
356	− 12.9	− 8.8	− 4.1
541	− 12.7	− 9.8	− 2.9
542	− 12.8	− 11.1	− 1.7
1780	− 13.3	− 11.7	− 1.6
2041	− 12.7	− 11.3	− 1.4
152	− 12.6	− 11.4	− 1.2
33	− 12.6	− 11.7	− 0.9
335	− 13	− 12.2	− 0.8
125	− 12.9	− 12.1	− 0.8
343	− 12.6	− 11.8	− 0.8
1006	− 12.8	− 12.2	− 0.6
1630	− 12.7	− 12.2	− 0.5
154	− 12.6	− 12.4	− 0.2

Assays were performed using Autodock VINA software, values are affinity energy (Kcal/mol)

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