Bulletin of the National Research Centre

Table 2 Binding affinity values of the imidazole analogues and R with SipA target

From: Design, pharmacokinetic profiling, and assessment of kinetic and thermodynamic stability of novel anti-Salmonella typhi imidazole analogues

Molecule ID	ΔG (kcal/mol)	Molecule ID	ΔG (kcal/mol)
1	− 5.5	10	− 6.4
2	− 5.7	11	− 6.3
3	− 5.4	12	− 6.1
4	− 5.9	13	− 6.7
5	− 5.5	14	− 5.7
6	− 6.3	15	− 5.9
7	− 6.2	B-1	− 7.8
8	− 6.4	B-2	− 7.6
9	− 5.8	R	− 6.8

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