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Bulletin of the National Research Centre

Table 1 The formulation factors and responses of Box–Behnken design for gallic acid nanoparticle

From: Enhancing cellular uptake and membrane permeability of gallic acid for breast cancer therapy via folate-tagged PEGylated iron oxide nanoparticles has theronastic agent

Factor

Name

Units

Level used (Low−1)

Level used (High + 1)

A:X1

Lipid conc

% w/v

1

4

B:X2

Polymer

% w/v

0.5

1

C:X3

Drug

Mg

5

25

Response

Name

Units

Goal

Y1

Particle size

Nm

Minimum

Y2

Entrapment efficiency

%

maximum

Y3

Drug release (48 h)

%

Maximum

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