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Table 1 The formulation factors and responses of Box–Behnken design for gallic acid nanoparticle

From: Enhancing cellular uptake and membrane permeability of gallic acid for breast cancer therapy via folate-tagged PEGylated iron oxide nanoparticles has theronastic agent

Factor Name Units Level used (Low−1) Level used (High + 1)
A:X1 Lipid conc % w/v 1 4
B:X2 Polymer % w/v 0.5 1
C:X3 Drug Mg 5 25
Response Name Units Goal
Y1 Particle size Nm Minimum
Y2 Entrapment efficiency % maximum
Y3 Drug release (48 h) % Maximum