Table 7 Phase IV 2001–2010:A decade exploring of α, β and γ cyclodextrins polymeric derivatives and utilization in novel drug delivery
From: Chronicle updates in cyclodextrin-based carriers for drug delivery
Sr. No. | Year | CD type | Polymer/encapsulate | Drug | Problem solved/purpose | Reference | |
|---|---|---|---|---|---|---|---|
1 | 2000 | HP-β-CD | Chitosan microsphere | Hydrocortisone | − | Filipovic et al. (2000) | |
2 | 2001 | HP-β-CD | Poly(alkylcyanoacrylate) nanoparticles | Saquinavir | To increase drug loading | Boudad et al. (2001) | |
3 | 2001 | β-CD | Microemulsion | Piroxicam | − | Dalmora et al. (2001) | |
4 | 2001 | γ-CD and DM- β –CD | Aerosol | Salbutamol | To evaluate delivery efficiency and toxicity of formulation in Aerosol | Srichana et al. (2001) | |
5 | 2002 | β-CD | Osmotic pump tablets | Glipizide | Constant delivery required | Gan et al. (2002) | |
6 | 2002 | 6A-O-[2-(3-Benzoylphenyl) propinoyl]-α-CD, HP-β-CD | Sustain release dosage form | Ketoprofen | Novel derivative of CD was studied | Kamada et al. (2002) | |
7 | 2003 | β-CD | Nanosphere | Bifonazole and clotrimazole | High load delivery of poorly soluble drugs | Memisoglu et al. (2003) | |
8 | 2004 | HP-β-CD | Buccoadhesive tablets | Piroxicam | To increase buccal bioavailability | Jug and Becirevic-Lacan (2004) | |
9 | 2005 | β-CD self-polymer, epichlorohydrin as spacer | Buccal delivery, bioadhesive polymer | Lidocaine and ketoprofen, lipophilic drugs | To check permeation of lipophilic drugs with novel polymer | Arakawa et al. (2005) | |
10 | 2009 | β-CD | Porphyrin conjugate | Doxorubicin | Photodynamic drug release | Kralova et al. (2009) | |