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Table 3 Effect of Ipomoea asarifolia ethanolic leaf extract on PTZ-induced seizures in mice

From: Anti-seizure properties of Ipomoea asarifolia (Desr.) (Convolvulaceae) ethanolic leaf extract in laboratory animals

Treatment (mg/kg)

Onset of seizures (Min.)

Quantal protection

Percentage protection

D/W 10 mL/kg

3.17 ± 0.48

0/6

0.00

IALE 150

4.33 ± 0.67

0/6

0.00

IALE 300

6.33 ± 0.95*

0/6

0.00

IALE 600

5.60 ± 0.40

1/6

16.67

V/A 200

8.33 ± 1.45**

3/6

50.00

  1. Data are presented as Mean ± S.E.M., * = p < 0.05, ** = p < 0.01 as compared to D/W group—One-way ANOVA followed by Dunnett’s post hoc test, n = 6, D/W = Distilled water, IALE = Ipomoea asarifolia leaf extract, V/A = Valproic acid