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Table 5 Protective effect of coconut water on antioxidant enzymes of carbon tetrachloride-induced toxicity in male (A) and female (B) rats

From: Protective effects of coconut water against the intraperitoneal infused carbon tetrachloride-induced toxicity—evaluations of biochemical, haematological and histopathological profiles in rats

Parameters

Normal control

CCl4 only

Coconut water (mL/kg)

2 mL/kg

4 mL/kg

6 mL/kg

A

     

GSH (U/L)

49.53 ± 1.81a

46.98 ± 2.67b

48.13 ± 3.06a

49.35 ± 1.16a

49.67 ± 2.35a

SOD (U/L)

21.97 ± 2.48a

17.94 ± 1.52b

18.52 ± 1.03b

21.82 ± 0.65a

22.44 ± 0.81a

CAT (U/L)

12.52 ± 2.12a

10.35 ± 0.75b

10.89 ± 0.79b

12.63 ± 0.77a

11.62 ± 0.85a

MDA (U/L)

0.51 ± 0.06a

0.99 ± 0.10b

0.98 ± 0.13b

0.81 ± 0.06b

0.81 ± 0.05b

B

     

GSH (U/L)

48.55 ± 4.03a

45.25 ± 2.71b

49.49 ± 3.47a

51.36 ± 0.88a

52.49 ± 1.71a

SOD (U/L)

22.85 ± 1.60a

19.81 ± 1.55b

22.37 ± 0.53a

22.57 ± 1.31a

24.26 ± 0.81c

CAT (U/L)

12.31 ± 1.11a

10.56 ± 0.60b

11.05 ± 1.31a

12.17 ± 0.19a

11.89 ± 1.00a

MDA (U/L)

0.66 ± 0.05a

1.09 ± 0.11b

0.88 ± 0.04c

0.87 ± 0.06c

0.77 ± 0.03c

  1. GSH, glutathione; SOD, superoxide dismutase; CAT, catalase; and MDA, malondialdehyde. Values in the row bearing the same letters of the alphabet are not statistically significant (p > 0.05) from one another. The data were analysed with one-way ANOVA and expressed as mean ± SD, then compared to controls, n = 6. Different letters (a, b or c) p < 0.05 both male and female rats show significant difference between the tested groups (2, 4 and 6 mL/kg) compared to the negative control