From: Computational analysis uncovers the deleterious SNPs along with the mutational spectrum of p53 gene and its differential expression pattern in pan-cancer
Mutation
Sign of DDG
DDG value prediction Kcal/mol
RI
RSA
S241F
Decrease
− 0.51
7
47.8
R248Q
− 0.93
9
88.6
R248W
− 0.58
5
R273H
− 1.62
20.5
R273C
− 1.52
8