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Table 9 I-mutant predictions for selected nsSNPs

From: Computational analysis uncovers the deleterious SNPs along with the mutational spectrum of p53 gene and its differential expression pattern in pan-cancer

Mutation

Sign of DDG

DDG value prediction Kcal/mol

RI

RSA

S241F

Decrease

− 0.51

7

47.8

R248Q

Decrease

− 0.93

9

88.6

R248W

Decrease

− 0.58

5

88.6

R273H

Decrease

− 1.62

9

20.5

R273C

Decrease

− 1.52

8

20.5