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Bulletin of the National Research Centre

Table 7 Functional residues in different functioning sites of p53 protein

From: Computational analysis uncovers the deleterious SNPs along with the mutational spectrum of p53 gene and its differential expression pattern in pan-cancer

Functioning site

Functioning residue with position

Zinc binding site

176C, 179H, 238C, 242C

Dimerization site

177P, 178H, 179H, 181R

DNA binding site

239N, 241S, 248R, 273R, 275C, 276A, 277C, 280R

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