Computational analysis uncovers the deleterious SNPs along with the mutational spectrum of p53 gene and its differential expression pattern in pan-cancer

Bulletin of the National Research Centre

Table 2 Further analysis of 16 SIFT predicted nsSNPs by PredictSNP (online tool)

SNP	Mutation	Predict SNP (%)	MAPP (%)	PhD-SNP (%)	PolyPhen-1 (%)	Polyphen-2 (%)	SIFT (%)	SNAP (%)	nsSNPAnalyzer (%)	PANTHER (%)
rs11540654	R110L	76	72	82	59	47	46	50	63	48
rs11540654	R110P	87	59	88	59	63	46	56	63	57
rs28934873	M133T	51	77	61	67	76	79	50	63	56
rs28934874	P151T	87	48	88	59	55	79	72	63	–
rs28934578	R175H	87	63	88	59	56	79	72	63	–
rs28934573	S241F	87	77	88	74	81	79	89	63	–
rs11540652	R248Q	87	59	88	59	81	53	81	65	–
rs121913342	R248W	87	77	88	74	81	79	85	65	–
rs28934571	R249S	87	77	88	74	81	53	81	63	–
rs28934577	L257Q	87	78	88	74	81	79	72	63	–
rs55832599	R267W	87	77	88	74	65	79	81	63	–
rs121913343	R273C	87	91	88	74	81	79	85	63	–
rs28934576	R273H	87	77	88	59	65	53	62	65	–
rs17849781	P278A	87	77	88	59	81	53	81	63	–
rs28934574	R282W	87	77	88	74	81	79	72	63	–
rs112431538	E285K	87	84	77	74	68	79	62	65	–