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Table 2 Effect of fructose administration on some physical variables of growing male and female Sprague-Dawley rats

From: Neonatal orally administered curcumin: impact on the metabolic response and renal histology of Sprague-Dawley rats fed a high-fructose diet until adolescence

Treatment groups

Abdominal circumference (cm)

Body Mass Index (g cm2)

Visceral fat absolute mass (g)

Visceral fat relative mass (%BM)

Epididymal fat absolute mass (g)

Epididymal fat relative mass (%BM)

Male rats

DMSO + TW

15.00 ± 0.67a

0.60 ± 0.01b

3.00 ± 0.22c

1.10 ± 0.11d

1.70 ± 0.08e

0.62 ± 0.03f

DMSO + FW

16.00 ± 0.19a

0.61 ± 0.01b

2.90 ± 0.55c

1.00 ± 0.07d

1.90 ± 0.09e

0.67 ± 0.03f

CC + TW

16.00 ± 0.59a

0.63 ± 0.02b

3.40 ± 0.42c

1.20 ± 0.15d

1.80 ± 0.13e

0.62 ± 0.03f

CC + FW

16.00 ± 0.49a

0.62 ± 0.02b

2.50 ± 0.40c

0.94 ± 0.13d

1.60 ± 0.19e

0.62 ± 0.05f

FW + TW

16.00 ± 0.45a

0.64 ± 0.02b

3.20 ± 0.55c

1.10 ± 0.22d

2.10 ± 0.17e

0.63 ± 0.02f

FW + FW

15.00 ± 0.42a

0.59 ± 0.02b

2.60 ± 0.34c

1.00 ± 0.10d

1.60 ± 0.09e

0.63 ± 0.02f

CCFW + TW

16.00 ± 0.55a

0.62 ± 0.02b

2.90 ± 0.39c

0.98 ± 0.13d

1.80 ± 0.15e

0.62 ± 0.03f

CCFW + FW

16.00 ± 0.46a

0.60 ± 0.02b

2.80 ± 0.49c

0.98 ± 0.14d

1.60 ± 0.23e

0.58 ± 0.06f

p values

0.441

0.372

0.764

0.887

0.241

0.472

Female rats

DMSO + TW

14.00 ± 0.58a

0.54 ± 0.02b

5.00 ± 0.47c

2.40 ± 0.22d

–

–

DMSO + FW

14.00 ± 0.31a

0.56 ± 0.02b

4.40 ± 0.58c

2.10 ± 0.24d

–

–

CC + TW

14.00 ± 0.43a

0.56 ± 0.01b

3.70 ± 0.37c

1.80 ± 0.17d

–

–

CC + FW

15.00 ± 0.26a

0.56 ± 0.01b

4.20 ± 0.29c

2.00 ± 0.13d

–

–

FW + TW

14.00 ± 0.36a

0.58 ± 0.02b

4.20 ± 0.54c

2.00 ± 0.31d

–

–

FW + FW

15.00 ± 0.31a

0.56 ± 0.02b

5.10 ± 0.23c

2.40 ± 0.10d

–

–

CCFW + TW

13.00 ± 0.57a

0.57 ± 0.01b

4.30 ± 0.49c

2.00 ± 0.19d

–

–

CCFW + FW

15.00 ± 0.28a

0.56 ± 0.01b

5.00 ± 0.50c

2.40 ± 0.19d

–

–

p values

0.095

0.744

0.212

0.175

–

–

  1. a, b, c, d, e, fMeans across columns (in males and females) with similar superscripts are similar (p > 0.05) using one-way ANOVA across all eight groups for abdominal circumference, BMI, absolute (g) and relative (BM) visceral fat mass, absolute (g) and relative (BM) epididymal fat pad mass of the male and female rats. BM = body mass. DMSO + TW = 10 ml kg−1 of a 0.5% dimethyl sulphoxide solution as neonates and plain tap water post-weaning, DMSO + FW = 10 ml kg−1 of a 0.5% dimethyl sulphoxide solution as neonates and fructose (20%, w/v) as drinking fluid post-weaning, CC + TW =  curcumin (500 mg kg−1 in 0.5% DMSO) as neonates and plain tap water post-weaning, CC + FW = curcumin (500 mg kg−1 in 0.5% DMSO) as neonates and fructose (20%, w/v) as drinking fluid post-weaning, FW + TW = fructose (20%, w/v) as neonates and plain tap water post-weaning, FW + FW = fructose (20%, w/v) as neonates and fructose (20%, w/v) as drinking fluid post-weaning, CCFW + TW = curcumin (500 mg kg−1) and fructose (20%, w/v) in 0.5% DMSO as neonates and plain tap water post-weaning, CCFW + FW = curcumin (500 mg kg−1) and fructose (20%, w/v) in 0.5% DMSO as neonates and fructose (20%, w/v) post-weaning. Data expressed as mean ± SEM, n = 7–9 per group