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Bulletin of the National Research Centre

Table 4 Solubility of the drug in different solvents

From: Formulation and optimization of polymeric agglomerates of Bosentan monohydrate by crystallo-co-agglomeration technique

Solvents

Solubility of drug (gm/ml)

Methanol

12 ± 0.5

Chloroform

522 ± 3.01

Acetonitrile

196.3 ± 1.5

Acetone

130.4 ± 1.07

Dichloromethane

570 ± 1.6

  1. Mean ± SD = 3
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