Skip to main content

Table 2 Effect of arsenic administration on haematological parameters of rats

From: Protective effects of methanolic extract of Andrographis paniculata (Burm.f.) Nees leaves against arsenic-induced damage in rats

Parameter

Control

Arsenic only

Arsenic + 200 mg/kg body weight A. paniculata

Arsenic + 200 mg/kg body weight ascorbic acid

WBC

10.13 ± 1.48

4.26 ± 0.71*

8.86 ± 2.46**

8.13 ± 2.56**

RBC

8.45 ± 0.26

5.31 ± 0.57*

7.508 ± 0.19**

7.02 ± 0.20**

HGB

13.65 ± 0.44

12.00 ± 0.54

12.30 ± 0.13

14.04 ± 0.86

HCT

46.05 ± 1.54

39.80 ± 1.44

40.78 ± 0.61

41.88 ± 3.25

LYM

85.05 ± 2.16

60.10 ± 2.67*

95.06 ± 0.72**

78.18 ± 2.05**

PLT

740.50 ± 98.50

341.70 ± 26.61*

714.50 ± 26.92**

833.00 ± 51.41**

MCV

57.24 ± 1.07

59.82 ± 1.88

54.36 ± 0.63

72.62 ± 1.06

MCH

16.70 ± 0.53

17.96 ± 0.49

16.94 ± 0.22

17.06 ± 1.460

MCHC

29.18 ± 0.55

30.04 ± 0.20

30.18 ± 0.28

37.29 ± 2.07

RDW-SD

27.06 ± 0.49

30.56 ± 1.40

27.58 ± 0.26

27.78 ± 0.25

RDW-CV

10.54 ± 0.77

11.92 ± 0.44

11.50 ± 0.44

10.08 ± 0.24

PDW

7.18 ± 0.11

7.70 ± 0.26

9.24 ± 0.24

10.09 ± 1.10

MPV

6.54 ± 0.20

6.76 ± 0.08

7.20 ± 0.08

6.90 ± 0.26

P-LCR

8.72 ± 0.46

9.50 ± 0.59

9.42 ± 0.73

10.77 ± 1.84

PTC

0.42 ± 0.07

0.39 ± 0.29

0.35 ± 0.02

0.50 ± 0.04

  1. Values are mean ± SEM (n = 6)
  2. *(p < 0.05) Group 2: (arsenic group rats) compared with group 1: (control rats)
  3. **(p < 0.05) Groups 3 and 4: (A. paniculata or ascorbic acid administered rats, respectively) compared with group 2: (arsenic group rats)