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Table 6 Threshold inhibitory concentration (IC50) of crude aqueous and methanol extracts of C. dependens and ascorbic acid standard on hydrogen peroxide radicals

From: Antiplasmodial and in vitro antioxidant potentials of crude aqueous and methanol extracts of Chasmanthera dependens (Hochst)

Extracts Threshold inhibitory concentration (*IC50) Mathematical model Equation R2
CDRM 0.90 ± 0.09 Sigmoid (a, b, c) \(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\) 0.931
CDLM 1.17 ± 0.17 Sigmoid (a, b, c) \(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\) 0.920
CDSM 1.16 ± 0.15 Sigmoid (a, b, c) \(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\) 0.915
CDRA 0.71 ± 0.07 Sigmoid (a, b, c) \(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\) 0.915
CDLA 0.93 ± 0.11 Sigmoid (a, b, c) \(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\) 0.911
CDSA 0.59 ± 0.11 Sigmoid (a, b, c) \(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\) 0.810
AA 0.38 ± 0.01 Logistic dose response (a, b, c) \(y=\frac{a}{1 +{\left(\frac{x}{b}\right)}^{c}}\) 0.999
  1. CDRM, C. dependens root methanol; CDLM, C. dependens leaves methanol; CDSM, C. dependens stem methanol; CDRA, C. dependens root aqueous; CDLA, C. dependens leaves aqueous; CDSA, C. dependens stem aqueous; AA, ascorbic acid
  2. *IC50 is the concentration of extract or standard that scavenged 50% of the generated free radicals