Antiplasmodial and in vitro antioxidant potentials of crude aqueous and methanol extracts of Chasmanthera dependens (Hochst)

Bulletin of the National Research Centre

Table 4 Threshold Inhibitory concentration (IC₅₀) of crude aqueous and methanolic extracts of leaves, stem and roots of C. dependens and ascorbic acid standard on DPPH radicals

Extracts	Threshold inhibitory concentration (*IC₅₀)	Mathematical model	Equation	R²
CDRM	1.81 ± 0.32	Sigmoid (a, b, c)	\(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\)	0.941
CDLM	1.44 ± 0.14	Sigmoid (a, b, c)	\(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\)	0.956
CDSM	1.52 ± 0.10	Sigmoid (a, b, c)	\(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\)	0.975
CDRA	1.10 ± 0.12	Sigmoid (a, b, c)	\(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\)	0.939
CDLA	1.81 ± 0.32	Sigmoid (a, b, c)	\(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\)	0.942
CDSA	1.51 ± 0.14	Sigmoid (a, b, c)	\(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\)	0.966
AA	0.58 ± 0.05	Sigmoid (a, b, c)	\(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\)	0.934

CDRM, C. dependens root methanol; CDLM, C. dependens leaves methanol; CDSM, C. dependens stem methanol; CDRA, C. dependens root aqueous; CDLA, C. dependens leaves aqueous; CDSA, C. dependens stem aqueous; AA, ascorbic acid
*IC₅₀ is the concentration of extract or standard that scavenged 50% of the generated free radicals