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Bulletin of the National Research Centre

Table 3 Hepatic parameters of rats following 28-day repeated administration of Culcasia angolensis leaves extract (CAE)

From: Preliminary sub-acute toxicological assessment of methanol leaves extract of Culcasia angolensis (Araceae) in Wistar rats

Parameters

Treatment (mg/kg)

DW (1 ml/kg)

CAE (125)

CAE (250)

CAE (500)

ALT (IU/L)

26.2 ± 4.11

27.2 ± 7.20

15.1 ± 1.57*

16.3 ± 2.07*

AST (IU/L)

37.67 ± 0.92

41.68 ± 0.58*

44.80 ± 1.67*

59.66 ± 2.28*

ALP (IU/L)

22.76 ± 3.38

19.68 ± 4.32

15.80 ± 3.24*

19.21 ± 4.03

TP (mg/dL)

6.54 ± 0.24

6.69 ± 0.32

6.44 ± 0.30

6.93 ± 0.34

ALB (mg/dL)

3.14 ± 0.07

3.17 ± 0.08

3.08 ± 0.06

3.03 ± 0.09

  1. The values were tabulated as mean ± SEM, *p ≤ 0.05 in relation to control group (one-way ANOVA followed by Dunnett's post hoc test), n = 6
  2. DW distilled water, ALT alanine transaminase, AST aspartate transaminase, ALP alkaline phosphatase, TP total protein, ALB albumin, CAE Culcasia angolensis leaves extract
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