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Table 3 Hepatic parameters of rats following 28-day repeated administration of Culcasia angolensis leaves extract (CAE)

From: Preliminary sub-acute toxicological assessment of methanol leaves extract of Culcasia angolensis (Araceae) in Wistar rats

Parameters Treatment (mg/kg)
DW (1 ml/kg) CAE (125) CAE (250) CAE (500)
ALT (IU/L) 26.2 ± 4.11 27.2 ± 7.20 15.1 ± 1.57* 16.3 ± 2.07*
AST (IU/L) 37.67 ± 0.92 41.68 ± 0.58* 44.80 ± 1.67* 59.66 ± 2.28*
ALP (IU/L) 22.76 ± 3.38 19.68 ± 4.32 15.80 ± 3.24* 19.21 ± 4.03
TP (mg/dL) 6.54 ± 0.24 6.69 ± 0.32 6.44 ± 0.30 6.93 ± 0.34
ALB (mg/dL) 3.14 ± 0.07 3.17 ± 0.08 3.08 ± 0.06 3.03 ± 0.09
  1. The values were tabulated as mean ± SEM, *p ≤ 0.05 in relation to control group (one-way ANOVA followed by Dunnett's post hoc test), n = 6
  2. DW distilled water, ALT alanine transaminase, AST aspartate transaminase, ALP alkaline phosphatase, TP total protein, ALB albumin, CAE Culcasia angolensis leaves extract