Fig. 10

A Brain tissue of mice treated with (R + COF + PQ) showing prominent cellularity with numerous pyramidal pigmented neuronal cells (black arrow); however, still, residual vacuolar degeneration was observed in the background (white arrow). B Brain tissue of mice treated with (R + COF + PQ) showing restored cellularity; however, pigmented pyramidal neuronal cells still showed some changes with irregular contour (black arrows). C Brain tissue of mice treated with (R + COF + PQ) showing organized, yet hypocellular Purkinje cell layer (black arrow) with adjacent numerous oligodendroglial cells (white arrow). D Brain cerebellar tissue of mice treated with (R + COF + PQ) showing preserved, organized, cellular, granular layer (black arrow) (H&E X400)