Chemo-informatics activity prediction, ligand based drug design, Molecular docking and pharmacokinetics studies of some series of 4, 6-diaryl-2-pyrimidinamine derivatives as anti-cancer agents

Bulletin of the National Research Centre

Table 2 Standard minimum proposed value used to assess a quantifiable QSAR model

Symbol	Name	Value
R²	Correlation coefficient	≥ 0.6
P_(95%)	Confidence interval at 95% confidence level	< 0.05
Q²	Cross validation coefficient	≥ 0.5
R²–Q²	Difference between R² and Q²	≤ 0.3
N_{ext test set}	Minimal number of external validation set	≥ 5
R²_ext	Correlation coefficient for external validation set	≥ 0.6