In vitro study of protective effect of Pterocarpus erinaceus Poir. stem bark and Amaranthus spinosus L. root extracts on cataractogenesis and glomerulopathy

Bulletin of the National Research Centre

Table 1 Biochemical parameters in lenses

Biochemical parameters	MDA (nM/mg protein)	GSH (µg/mg protein)	CAT (kU/l)
NC	0.0054 ± 0.0006	7.7233 ± 0.1308	6.5030 ± 0.4013
TC	0.0343 ± 0.0003^{# #}	2.8506 ± 0.1290^{# # #}	1.3610 ± 0.2720^{# # # #}
P. erinaceus 500 mg/kg	0.0065 ± 0.0004**	6.8848 ± 0.1064***	8.8995 ± 0.6008****
P. erinaceus 250 mg/kg	0.0101 ± 0.0006**	5.0365 ± 0.1767**	4.5107 ± 0.4040**
A. spinosus 500 mg/kg	0.0049 ± 0.0003****	7.6180 ± 0.1014***	9.9106 ± 0.5719****
A. spinosus 250 mg/kg	0.0055 ± 0.0002***	3.7778 ± 0.1424**	8.6349 ± 0.4401****
Rutin 500 µg/kg	0.0041 ± 0.0008****	6.3668 ± 0.1160***	8.5134 ± 0.8131****

NC = normal control; TC = toxic control; MDA = malondialdehyde; GSH = glutathione; CAT = catalase. Values were analyzed with a one-way ANOVA and then expressed as mean ± SEM. ^##p < 0.01; ^###p < 0.001; ^####p < 0.0001; compared to NC; **p < 0.01; ***p < 0.001; ****p < 0.0001; compared to TC. n = 5