Skip to main content

Table 3 Acute toxicity test (LD50) of the aqueous and methanolic extracts of the roots, leaves, and stem of Dictyandra arborescens at high doses of 1600, 2900 and 5000 mg/kg body weight

From: Oral acute toxicity and antimalarial potentials of aqueous and methanolic extracts of roots, leaves and stem of Dictyandra arborescens (Welw.) on Plasmodium berghei infected mice

Extracts

Number of animals per group

Doseof extract/Weight of mice (1600 mg/kg)

Signs of toxicity

Number of animals that survived

DARM

3

19 g

x

3/3

DARA

3

22 g

x

3/3

DALM

3

20 g

x

3/3

DALA

3

18 g

x

3/3

DASM

3

20 g

x

3/3

DASA

3

20 g

x

3/3

2900 mg/kg

DARM

3

20 g

x

3/3

DARA

3

21 g

x

3/3

DALM

3

21 g

x

3/3

DALA

3

21 g

x

3/3

DASM

3

23 g

x

3/3

DASA

3

22 g

x

3/3

5000 mg/kg

DARM

3

24 g

x

3/3

DARA

3

19 g

x

3/3

DALM

3

23 g

x

3/3

DALA

3

20 g

x

3/3

DASM

3

22 g

x

3/3

DASA

3

24 g

x

3/3

  1. DARM = D. arborescens root methanol, DARA = D.arborescens root aqueous, DALM = D.arborescens leaves methanol, DALA = D.arborescens leaves aqueous, DASM = D.arborescens stem methanol, DASA = D.arborescens stem aqueous, x = no sign of toxicity