Table 2 Relative levels of inhibition/activation of poly-dHbS-M by fractionated leaf extracts of A. occidentale, P. guajava, and T. catappa
[Extract fraction] | Relative inhibition/activation of polymerization (%) | |||||
|---|---|---|---|---|---|---|
30 s | 60 s | 90 s | 120 s | 150 s | 180 s | |
A. occidentale petroleum ether | ||||||
40 mg% | 9.76 ± 1.23 | 4.83 ± 0.73 | 5.76 ± 1.10 | 0.25 ± 0.05↑ | 0.31 ± 0.02↑ | 1.06 ± 0.02↑ |
60 mg% | 1.74 ± 0.02 | 7.10 ± 1.11 | 14.57 ± 1.12 | 16.49 ± 1.22 | 18.39 ± 1.11 | 18.65 ± 1.10 |
80 mg% | 0.38 ± 0.01 | 11.68 ± 0.89 | 10.43 ± 1.08 | 0.66 ± 0.01 | 1.43 ± 0.02↑ | 2.60 ± 0.88↑ |
A. occidentale n-hexane | ||||||
40 mg% | 3.70 ± 0.04 | 18.15 ± 1.21 | 2.96 ± 0.03 | 11.48 ± 1.10↑ | 28.52 ± 2.80↑ | 41.48 ± 3.87↑ |
60 mg% | 7.77 ± 1.56 | 25.19 ± 2.56 | 7.04 ± 1.16 | 0.37 ± 0.01↑ | 15.19 ± 1.80↑ | 32.59 ± 3.67↑ |
80 mg% | 4.81 ± 1.65 | 18.52 ± 2.01 | 27.41 ± 2.98 | 18.51 ± 2.07 | 3.33 ± 0.98 | 9.26 ± 1.67↑ |
A. occidentale chloroform | ||||||
40 mg% | 87.80 ± 4.90↑ | 59.83 ± 5.91↑ | 38.69 ± 2.10↑ | 31.25 ± 2.20↑ | 35.84±3.00↑ | 38.69 ± 4.01↑ |
60 mg% | 31.25 ± 3.67↑ | 29.17 ± 3.23↑ | 17.55 ± 1.10↑ | 20.24 ± 1.90↑ | 31.67 ± 3.00↑ | 29.76 ± 2.67↑ |
80 mg% | 16.97 ± 2.88↑ | 24.41 ± 3.11↑ | 46.43 ± 3.56 | 46.42 ± 2.56 | 32.31 ± 2.54 | 27.38 ± 2.56 |
A. occidentale ethylacetate | ||||||
40 mg% | 51.11 ± 4.98 | 90.00 ± 5.78 | 94.07 ± 6.98 | 81.85 ± 5.34 | 82.96 ± 4.87 | 79.26 ± 4.98 |
60 mg% | 38.51 ± 2.80 | 66.67±3.48 | 67.04 ± ± 3.95 | 52.96 ± 3.01 | 48.88 ± 3.89 | 43.71 ± 2.69 |
80 mg% | 13.33 ± 1.80 | 22.22 ± 2.00 | 5.18 ± 1.01↑ | 17.41 ± 1.90↑ | 31.85 ± 2.50↑ | 26.67 ± 2.11↑ |
A. occidentale residual aqueous | ||||||
40 mg% | 36.64 ± 3.00↑ | 101.13 ± 7.9↑ | 160.61 ± 8.9↑ | 129.53 ± 7.1↑ | 87.03 ± 4.10↑ | 29.93 ± 2.78 |
60 mg% | 20.59 ± 2.00↑ | 119.63 ± 9.7↑ | 103.75 ± 7.9↑ | 98.44 ± 5.40↑ | 363.18 ± 11.8 | 612.46 ± 15.9 |
80 mg% | 9.28 ± 1.76↑ | 105.26 ± 8.6↑ | 120.11 ± 8.9↑ | 43.34 ± 2.52 | 210.72 ± 10.7 | 563.95 ± 13.8 |
P. guajava petroleum ether | ||||||
40 mg% | 72.62 ± 3.50↑ | 73.22 ± 2.89↑ | 56.25 ± 4.97↑ | 67.86 ± 3.55↑ | 84.06 ± 4.01↑ | 103.27 ± 7.4↑ |
60 mg% | 63.10 ± 4.10↑ | 70.54 ± 4.92↑ | 51.48 ± 3.87↑ | 58.34 ± 2.98↑ | 67.69 ± 4.91↑ | 75.30 ± 3.77↑ |
80 mg% | 70.83 ± 3.80↑ | 75.16 ± 3.78↑ | 49.99 ± 2.99↑ | 40.48 ± 3.32↑ | 42.39 ± 4.11↑ | 58.93 ± 4.54↑ |
P. guajava n-hexane | ||||||
40 mg% | 38.68 ± 2.98 | 38.31 ± 3.00 | 34.71 ± 2.09 | 28.33 ± 2.98 | 27.15 ± 2.67 | 27.54 ± 2.67 |
60 mg% | 16.00 ± 1.76 | 23.90 ± 1.98 | 25.54 ± 1.77 | 25.39 ± 2.00 | 25.79 ± 2.08 | 34.53 ± 2.33 |
80 mg% | 22.60 ± 2.76 | 28.56 ± 2.78 | 34.23 ± 3.03 | 43.94 ± 3.66 | 49.57 ± 3.89 | 51.73 ± 4.03 |
P. guajava chloroform | ||||||
40 mg% | 1.10 ± 0.09↑ | 2.19 ± 0.86↑ | 5.37 ± 0.98 | 11.51 ± 1.09 | 23.72 ± 2.04 | 29.10 ± 2.54 |
60 mg% | 20.56 ± 2.40↑ | 7.64 ± 0.99 | 22.00 ± 2.03 | 25.87 ± 1.78 | 24.23 ± 2/12 | 19.59 ± 2.03 |
80 mg% | 14.81 ± 1.10↑ | 5.08 ± 0.89↑ | 10.42 ± 1.21 | 15.85 ± 1.78 | 23.13 ± 2.21 | 30.84 ± 2.78 |
P. guajava ethylacetate | ||||||
40 mg% | 4.31 ± 0.09↑ | 14.75 ± 1.02 | 31.03 ± 2.45 | 45.10 ± 3.11 | 55.01 ± 3.08 | 67.73 ± 3.98 |
60 mg% | 17.53 ± 1.60↑ | 11.84 ± 1.22↑ | 5.60 ± 0.98↑ | 8.59 ± 1.12↑ | 7.76 ± 1.11↑ | 5.68 ± 0.93↑ |
80 mg% | 9.93 ± 1.02 | 15.93 ± 1.65 | 31.07 ± 2.34 | 31.06 ± 2.01 | 31.32 ± 2.33 | 37.00 ± 3.09 |
P. guajava residual aqueous | ||||||
40 mg% | 22.01 ± 1.98 | 16.46 ± 1.56 | 17.29 ± 1.45 | 17.57 ± 1.87 | 33.18 ± 2.45↑ | 69.53 ± 5.34↑ |
60 mg% | 18.38 ± 1.78 | 3.86 ± 1.32 | 3.54 ± 0.89 | 0.83 ± 0.08 | 57.40 ± 2.78↑ | 100.73 ± 8.8↑ |
80 mg% | 8.08 ± 0.78↑ | 14.82 ± 1.78↑ | 12.84 ± 1.04↑ | 32.38 ± 2.02↑ | 100.53 ± 8.5↑ | 143.88 ± 9.8↑ |
T. catappa petroleum ether | ||||||
40 mg% | 12.63 ± 1.40↑ | 44.78 ± 3.59↑ | 40.91 ± 4.0↑ | 22.06 ± 2.11↑ | 6.39 ± 1.23↑ | 2.02 ± 0.21↑ |
60 mg% | 27.61±2.20↑ | 57.07 ± ± 4.78↑ | 55.22 ± 5.2↑ | 24.25 ± 2.19↑ | 11.62 ± 1.05 | 39.90 ± 2.56 |
80 mg% | 9.43 ± 0.56↑ | 45.96 ± 4.98↑ | 26.43 ± 3.1↑ | 2.18 ± 0.09 | 28.46 ± 1.45 | 49.50 ± 3.67 |
T. catappa n-hexane | ||||||
40 mg% | 11.07 ± 1.9↑ | 5.81 ± 1.09↑ | 9.91 ± 1.08 | 8.88 ± 0.95 | 9.21 ± 0.17 | 9.21 ± 0.95 |
60 mg% | 0.61 ± 0.03↑ | 8.23 ± 0.85↑ | 5.41 ± 0.09 | 11.00 ± 0.87 | 18.31 ± 2.01 | 6.50 ± 0.98 |
80 mg% | 9.46 ± 0.97↑ | 19.16 ± 1.56↑ | 6.21 ± 1.54↑ | 5.99 ± 1.04 | 15.06 ± 1.67 | 16.81 ± 2.45 |
T. catappa chloroform | ||||||
40 mg% | 9.46 ± 1.06↑ | 0.96 ± 0.02 | 1.35 ± 0.08↑ | 1.46 ± 0.09 | 9.87 ± 0.89↑ | 8.33 ± 1.02↑ |
60 mg% | 7.29 ± 0.09↑ | 11.13±1.78 | 3.18 ± 0.45 | 1.46 ± 0.06 | 0.09 ± 0.001↑ | 1.89 ± 0.08↑ |
80 mg% | 0.19 ± 0.09↑ | 16.02 ± 1.98 | 6.64 ± 1.07 | 8.32 ± 1.44 | 1.57 ± 0.07 | 6.44 ± 0.98 |
T. catappa ethylacetate | ||||||
40 mg% | 2.53 ± 0.88 | 8.91 ± 1.05 | 2.05 ± 0.18 | 13.23 ± 2.01↑ | 12.21 ± 1.05↑ | 19.55 ± 2.01↑ |
60 mg% | 18.76 ± 1.78 | 10.34 ± 0.98 | 13.85 ± 0.88 | 2.74 ± 0.31 | 5.23 ± 0.55 | 11.22 ± 0.67 |
80 mg% | 24.72 ± 2.01 | 34.13 ± 2.02 | 40.13 ± 3.11 | 39.11 ± 2.11 | 44.33 ± 3.02 | 41.19 ± 2.67 |
T. catappa residual aqueous | ||||||
40 mg% | 17.69 ± 1.6↑ | 22.80 ± 1.01↑ | 23.82 ± 1.2↑ | 15.83 ± 0.78↑ | 42.94 ± 3.18↑ | 46.95 ± 3.55↑ |
60 mg% | 9.91 ± 1.03 | 7.39 ± 0.98 | 3.07 ± 0.56 | 5.91 ± 0.76 | 32.43 ± 3.67↑ | 56.38 ± 4.01↑ |
80 mg% | 2.19 ± 0.86 | 17.09 ± 1.56 | 13.51 ± 1.11 | 17.61 ± 1.14 | 22.17 ± 1.45↑ | 53.56 ± 3.86↑ |