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Table 1 Serum VEGF (ng/L) activity among the studied groups

From: The role of VEGF and BMP-2 in stimulation of bone healing with using hybrid bio-composite scaffolds coated implants in animal model

Parameters Groups
Group I Group II Group III IV
Control CH (NM) CH (M) CH.BG (NM) CH.BG (M)
Range 0.037-2.624 0.971-2.837 0.778-2.669 0.701-1.347
Pre-surgery     
Mean ± S.D 2.18 ± 0.106 2.951 ± 0.011 2.624 ± 0.111 3.173 ± 0.01
(2-week)     
Mean ± S.D 6.957 ± 0.264 8.495 ± 0.005 4.784 ± 0.287 3.2 ± 0.022
P value   < 0.001* NS NS
(3-week)     
Mean ± S.D 7.328 ± 0.103 4.013 ± 0.581 7.223 ± 0.229 2.699 ± 0.111
P value   NS < 0.001** NS
(4-week)     
Mean ± S.D 6.701 ± 0.129 5.695 ± 0.168 4.166 ± 0.251 2.667 ± 0.05
P value   < 0.001* < 0.05** < 0.05***
(5-week)     
Mean ± S.D 6.081 ± 0.035 5.053 ± 0.024 6.712 ± 0.231 2.528 ± 0.054
P value   < 0.001* < 0.001** < 0.05***
(6-week)     
Mean ± S.D 6.01 ± 0.07 4.806 ± 0.016 6.766 ± 0.265 3.143 ± 0.167
P value   < 0.001* = 0.001** NS
(7-week)     
Mean ± S.D 6.161 ± 0.031 6.158 ± 0.408 7.224 ± 0.054 3.274 ± 0.221
P value   < 0.05* < 0.001** NS
(8-week)     
Mean ± S.D 5.902 ± 0.061 7.144 ± 0.091 6.864 ± 0.033 2.471 ± 0.124
P value   < 0.001* < 0.001** < 0.05***
(9-week)     
Mean ± S.D 5.262 ± 0.014 7.179 ± 0.027 6.612 ± 0.163 2.51 ± 0.082
P value   < 0.001* < 0.001** < 0.05***
(10-week)     
Mean ± S.D. 4.953 ± 0.077 7.064 ± 0.01 7.169 ± 0.216 2.635 ± 0.111
P value   < 0.001* < 0.001** NS
(11-week)     
Mean ± S.D. 4.621 ± 0.026 5.496 ± 0.234 6.5 ± 0.047 2.156 ± 0.015
P value   < 0.001* < 0.001** < 0.001***
(12-week)     
Mean ± S.D. 4.614 ± 0.091 6.952 ± 0.244 6.504 ± 0.048 2.566 ± 0.108
P value   < 0.001* < 0.001** < 0.05***
  1. P > 0.05 is non-significant, P ≤ 0.05 is significant, P ≤ 0.001 is highly significant, NS non-significant
  2. *P value of group I versus group II
  3. **P value of group I versus group III
  4. ***P value of group I versus group IV