Table 1 Serum VEGF (ng/L) activity among the studied groups

Range

0.037-2.624

0.971-2.837

0.778-2.669

0.701-1.347

Pre-surgery

Mean ± S.D

2.18 ± 0.106

2.951 ± 0.011

2.624 ± 0.111

3.173 ± 0.01

(2-week)

Mean ± S.D

6.957 ± 0.264

8.495 ± 0.005

4.784 ± 0.287

3.2 ± 0.022

P value

< 0.001*

NS

NS

(3-week)

Mean ± S.D

7.328 ± 0.103

4.013 ± 0.581

7.223 ± 0.229

2.699 ± 0.111

P value

NS

< 0.001**

NS

(4-week)

Mean ± S.D

6.701 ± 0.129

5.695 ± 0.168

4.166 ± 0.251

2.667 ± 0.05

P value

< 0.001*

< 0.05**

< 0.05***

(5-week)

Mean ± S.D

6.081 ± 0.035

5.053 ± 0.024

6.712 ± 0.231

2.528 ± 0.054

P value

< 0.001*

< 0.001**

< 0.05***

(6-week)

Mean ± S.D

6.01 ± 0.07

4.806 ± 0.016

6.766 ± 0.265

3.143 ± 0.167

P value

< 0.001*

= 0.001**

NS

(7-week)

Mean ± S.D

6.161 ± 0.031

6.158 ± 0.408

7.224 ± 0.054

3.274 ± 0.221

P value

< 0.05*

< 0.001**

NS

(8-week)

Mean ± S.D

5.902 ± 0.061

7.144 ± 0.091

6.864 ± 0.033

2.471 ± 0.124

P value

< 0.001*

< 0.001**

< 0.05***

(9-week)

Mean ± S.D

5.262 ± 0.014

7.179 ± 0.027

6.612 ± 0.163

2.51 ± 0.082

P value

< 0.001*

< 0.001**

< 0.05***

(10-week)

Mean ± S.D.

4.953 ± 0.077

7.064 ± 0.01

7.169 ± 0.216

2.635 ± 0.111

P value

< 0.001*

< 0.001**

NS

(11-week)

Mean ± S.D.

4.621 ± 0.026

5.496 ± 0.234

6.5 ± 0.047

2.156 ± 0.015

P value

< 0.001*

< 0.001**

< 0.001***

(12-week)

Mean ± S.D.

4.614 ± 0.091

6.952 ± 0.244

6.504 ± 0.048

2.566 ± 0.108

P value

< 0.001*

< 0.001**

< 0.05***