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Table 3 Curative effect of Morinda lucida and Alstonia boonei plant extracts and chloroquine against P. berghei infection in mice for five consecutive days

From: Antiplasmodial activities of Morinda lucida (Benth) and Alstonia boonei (De wild) in mice infected with Plasmodium berghei

Treatment groups

Percentage parasitemia

Days

1

2

3

4

5

M. lucida, 400 mg

2.40 ± 0.24a

3.60 ± 0.24d

3.00 ± 0.32c

1.60 ± 0.24bcd

0.40 ± 0.20ab

M. lucida, 600 mg

4.40 ± 0.24bcde

5.40 ± 0.24e

2.0 ± 0.32bc

1.60 ± 0.24bcd

1.40 ± 0.24ab

M. lucida, 800 mg

2.20 ± 0.20a

4.80 ± 0.37e

2.60 ± 0.40c

2.40 ± 0.24d

1.20 ± 0.58ab

A. boonie, 400 mg

3.80 ± 0.37abcd

1.20 ± 0.20a

1.20 ± 0.20ab

1.00 ± 0.00abc

1.00 ± 0.32ab

A. boonie, 600 mg

2.80 ± 1.07ab

1.60 ± 0.40ab

1.20 ± 0.37ab

0.60 ± 0.24ab

0.40 ± 0.24ab

A. boonie, 800 mg

6.00 ± 0.32e

3.20 ± 0.20cd

2.20 ± 0.20bc

2.00 ± 0.32cd

1.60 ± 0.40ab

Combined recipe, 400 mg

3.20 ± 0.37abc

0.80 ± 0.20a

1.0 ± 0.32ab

0.60 ± 0.24ab

0.80 ± 0.37ab

Combined recipe, 600 mg

3.80 ± 0.97abcd

2.20 ± 0.58bc

2.20 ± 0.80bc

1.60 ± 0.60bcd

0.40 ± 0.24ab

Combined recipe, 800 mg

5.80 ± 0.49e

2.60 ± 0.24bcd

0.60 ± 0.24a

0.60 ± 0.24ab

0.40 ± 0.24ab

Chloroquine, 10 mg/kg

5.40 ± 0.24de

2.60 ± 0.24bcd

0.00 ± 0.00a

0.00 ± 0.00a

0.00 ± 0.00a

Infected Untreated

4.80 ± 0.37cde

7.00 ± 0.44f

11.40 ± 0.60d

13.60 ± 0.87e

18.40 ± 0.98b

  1. Mean ± standard error represents 5 replicates. Mean values down the column with the same alphabet are not significantly different from each other at P > 0.05