Bulletin of the National Research Centre

Table 6 Genotype frequency of C-1214G polymorphism of SDH gene in relation to severity (NPDR and PDR) of retinopathy in both genders

From: Role of advanced glycation end products and sorbitol dehydrogenase in the pathogenesis of diabetic retinopathy

		C-1214 G of SDH
Retinal state		CC		CG		GG		Pvalue
(Males)	No	3	20.0%	10	66.7%	2	13.3%	0.386
	NPDR	1	4.2%	16	66.7%	7	29.2%
	PDR	6	20.7%	16	55.2%	7	24.1%
(Females)	No	1	2.7%	27	73.0%	9	24.3%	0.05
	NPDR	7	21.9%	15	46.9%	10	31.3%
	PDR	9	23.7%	22	57.9%	7	18.4%

There was no statistically significant difference between the three genotypes (CC, CG, and GG) in relation to DR severity in male genders. However, there was a statistically significant difference in female gender with increased frequency of CC genotype (2.7%, 21.9%, and 23.7%)

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