Role of advanced glycation end products and sorbitol dehydrogenase in the pathogenesis of diabetic retinopathy

Bulletin of the National Research Centre

Table 1 Clinical characteristics of patients grouped according to the presence of DR

Clinical features of type I DM patients grouped according to the presence or absence of DR that are shown in Table 1. Patients with no DR had a shorter duration of DM and were younger than patients with DR. Gender proportion did not differ significantly among groups. The study revealed no significant correlation of gender, education, family history of diabetes, consanguinity, ischemic heart disease, nephropathy, and neuropathy to DR, whereas family history of DR and hypertension were correlated to retinopathy, and there was a highly significant correlation of duration of diabetes to retinopathy.