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Table 6 Shows liver and kidney functions of serum Bisphenol A-intoxicated rats treated with Fagonia cretica extract

From: Enhancement effects of ethanolic extract of Fagonia cretica on Bisphenol A (BPA)-induced genotoxicity and biochemical changes in rats

Treatment

AST (lU/l)

ALT (lU/l)

Alph (lU/l)

Bilirubin (g/dl)

Urea mg/dl

Creatinine mg/dl

Normal control

47.40 ± 0.92f

51.20 ± 0.86g

153.91 ± 0.79h

0.28 ± 0.01d

22.93 ± 0.37g

0.623 ± 0.01d

Control oil treatment

47.20 ± 0.86f

50.80 ± 0.86g

153.43 ± 0.87h

0.27 ± 0.01d

21.04 ± 0.40g

0.625v0.01d

Bisphenol A (BPA)

81.00 ± 1.22a

101.40 ± 1.72a

415.99 ± 5.02a

1.33 ± 0.1a

54.82 ± 0.48a

1.27 ± 0.06a

Protective low dose of FCE

52.00 ± 0.70c

62.80 ± 0.86c

213.06 ± 2.17e

0.36v0.01bcd

28.96 ± 0.38d

0.719 ± 0.01bc

Protective medium dose of FCE

58.20 ± 1.39g

61.00 ± 0.70ef

199.43 ± 1.79f

0.34 ± 0.01cd

27.52 ± 0.28e

0.719 ± 0.17bc

Protective high dose of FCE

55.00 ± 0.70c

58.60 ± 0.51f

187.37 ± 1.18g

0.31 ± 0.01cd

25.63 ± 0.50f

0.68 ± 0.005cd

Therapeutic low dose of FCE

69.00 ± 0.70b

73.80 ± 0.58b

243.87 ± 4.72b

0.45 ± 0.14b

34.11 ± 0.35b

0.783 ± 0.01b

Therapeutic medium dose of FCE

68.00 ± 0.94b

70.60 ± 0.51c

234.27 ± 2.40c

0.41 ± 0.01bc

31.90 ± 0.50c

0.758 ± 0.01bc

Therapeutic high dose of FCE

64.00 ± 0.70c

67.20 ± 0.86d

223.23 ± 1.93d

0.39 ± 0.01bc

30.88 ± 0.39c

0.737 ± 0.01bc

  1. All data are expressed as mean ± SE. Means with different superscripts letters a, b, c are significantly different at P ≤ 0.05