Skip to main content

Table 3 Shows the enhancement role of Fagonia cretica extract (FCE) on Bisphenol A-induced chromosomal aberrations in rats

From: Enhancement effects of ethanolic extract of Fagonia cretica on Bisphenol A (BPA)-induced genotoxicity and biochemical changes in rats

Treatment

Structural chromosomal aberrations

Aneuploidy

Total aberrations

Gap

Break

Deletion & fragment

Centromeric attenuation

Endomitosis

Total structural

Normal control

1.0 ± 0.32d

0.40 ± 0.24f

0.40 ± 0.25d

0.60 ± 0.40e

0.20 ± 0.20d

2.60 ± 0.81f

0.60 ± 0.25d

3.20 ± 0.80f

Control oil treatment

1.20 ± 0.37d

0.80 ± 0.37ef

0.40 ± 0.25d

1.0 ± 0.45e

0.60 ± 0.25cd

4.0 ± 0.44f

0.60 ± 0.25d

4.60 ± 0.51f

Bisphenol A (BPA)

5.40 ± 0.75a

3.60 ± 0.51a

4.80 ± 0.74a

7.20 ± 0.37a

3.0 ± 0.32a

24.0 ± 1.22a

5.40 ± 0.68a

29.40 ± 0.68a

Protective low dose of FCE

2.80 ± 0.37c

2.20 ± 0.20bcd

1.40 ± 0.40cd

5.40 ± 0.51b

2.20 ± 0.49ab

14.0 ± 0.63cd

3.40 ± 0.40b

17.40 ± 0.51c

Protective medium dose of FCE

2.80 ± 0.20c

1.80 ± 0.37cde

1.40 ± 0.25cd

4.40 ± 0.40bc

2.0 ± 0.32ab

12.0 ± 0.63d

2.40 ± 0.51bc

14.40 ± 0.81d

Protective high dose of FCE

2.0 ± 0.32 cd

1.20 ± 0.37def

1.0 ± 0.32cd

2.40 ± 0.51d

1.60 ± 0.51bc

8.60 ± 0.87e

1.80 ± 0.37cd

10.40 ± 1.0e

Therapeutic low dose of FCE

5.0 ± 0.32ab

3.0 ± 0.45ab

4.20 ± 0.37ab

3.40 ± 0.40cd

2.40 ± 0.51ab

18.0 ± 1.18b

5.20 ± 0.66a

23.20 ± 0.86b

Therapeutic medium dose of FCE

4.0 ± 0.32b

2.60 ± 0.26abc

3.20 ± 0.20b

3.0 ± 0.55d

3.0 ± 0.32a

15.60 ± 0.75bc

3.60 ± 0.51b

18.80 ± 0.86c

Therapeutic high dose of FCE

2.20 ± 0.37 cd

2.20 ± 0.37bcd

2.0 ± 0.32c

2.60 ± 0.40d

2.80 ± 0.20a

11.80 ± 1.0d

2.60 ± 0.51bc

14.40 ± 0.41d

  1. All data are expressed as mean ± SE. Means with different superscripts letters a, b, c, d, e, f are significantly different at P ≤ 0.05