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Table 1 General characteristics of the studied groups

From: Valsartan reduces NOX4 expression and halts diabetic nephropathy in streptozotocin induced diabetic rat model

Groups variable (mean ± SEM)

GpI

GpII

GpIII

Body weight (g) (start point)

276.4 ± 10.02

266.4 ± 9

261 ± 8

Body weight (g) (end point)

268.35 ± 9.88

248.05 ± 12.21

266.75 ± 10.01

Fluid intake (ml/24 h)

39.66 ± 0.98

214 ± 10.23**

64.7 ± 1.18##

Food intake (mg/24 h)

29.4 ± 2.4

52.16 ± 1.88**

37 ± 1.27##

Kidney weight(g)

0.49 ± 0.02

1.03 ± 0.028**

0.84 ± 0.038##

KW/BW (g/kg)

1.75 ± 0.1

4.3 ± 0.23**

3.1 ± 0.17##

  1. Values are mean ± SEM, statistically significant difference, **p, ##p ˂ 0.01, (*) compared to GpI: normal group, (#) compared to GpII: DN group. Start point: at the beginning of the experiment before induction of diabetes. End point: at the end of experiment before scarification of rat. KW kidney weight, BW body weight