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Table 4 Mean values ± S.D. of lens glutathione (GSH), malondialdehyde (MDA), and total antioxidant capacity (TAC) in control and experimental groups

From: Potential prophylactic effect of chemical chaperones for alleviation of endoplasmic reticulum stress in experimental diabetic cataract

Groups

GSH (μmol/g tissue)

MDA (nmol/g tissue)

TAC (μmol/g tissue)

Group 1: control

 Range

4.68–8.95

5.76–7.21

0.61–2.61

 Mean ± S.D

7.08 ± 1.73

6.23 ± 0.62

1.37 ± 0.77

Group 2: diabetic model

 Range

0.89–2.8

10.81–18.75

0.11–0.36

 Mean ± S.D

1.7 ± 0.74a

15.71 ± 3.2a

0.18 ± 0.09a

Group 3: diabetic model + 4PBA

 Range

1.83–7.53

5.76–9.61

0.2–1.55

 Mean ± S.D

4.52 ± 1.97a,b

7.68 ± 1.9b

0.77 ± 0.44a,b

Group 4: diabetic model + TUDCA

 Range

2.3–7.53

6.73–10.81

0.06–0.73

 Mean ± S.D

4.85 ± 1.87a,b

8.45 ± 1.7b

0.54 ± 0.25a

Group 5: diabetic model + TMAO

 Range

0.89–4.68

8.41–17.3

0.05–0.36

 Mean ± S.D

2.31 ± 1.33a

13.3 ± 3.5a

0.19 ± 0.11a

  1. SD standard deviation n = 15
  2. aSignificant in comparing with control group at P < 0.05
  3. bSignificant in comparing with diabetic model group at P < 0.05