Potential prophylactic effect of chemical chaperones for alleviation of endoplasmic reticulum stress in experimental diabetic cataract

Bulletin of the National Research Centre

Table 2 Study of plasma fasting blood sugar (FBS), serum insulin, and resistance (HOMA-IR) in control and experimental groups

Groups	FBS mg/dl	Insulin μIU/ml	HOMA-IR
Group 1: control
Range	7.9–99	20–32.5	3.9–7.3
Mean ± S.D	88.6 ± 7.14	24.84 ± 4.92	5.37 ± 1.04
Group 2: diabetic model
Range	200–286	12–22.5	6.2–13.8
Mean ± S.D	231.6 ± 25.84^a	16.57 ± 3.73^a	9.46 ± 2.33^a
Group 3: diabetic model + 4PBA
Range	145–185	11.27–22.5	4–9.7
Mean ± S.D	164.53 ± 11.71^a,b	17.17 ± 4.06^a	6.9 ± 1.8^a,b
Group 4: diabetic model + TUDCA
Range	148–187	12.5–30.1	4.9–13.3
Mean ± S.D	168.53 ± 14.67^a,b	19.42 ± 5.28^a	8.1 ± 2.45^a
Group 5: diabetic model + TMAO
Range	164–232	11.3–27.5	5.1–12.8
Mean ± S.D	198.53 ± 24.21^a,b	18.28 ± 4.7^a	8.94 ± 2.55^a