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Table 4 GLUL polymorphism rs10911021 and characteristics of subjects among the studied groups

From: GLUL rs10911021 polymorphism and risk of coronary artery disease among Egyptian individuals

 

CAD with T2DM (N = 240)

CAD (N = 180)

T (%)

C (%)

p value

T (%)

C (%)

p value

Height (cm)

164.9 ± 9.9

167.9 ± 10

0.047*

168.24 ± 7.5

170.4 ± 7.4

0.064

Weight (kg)

91.49 ± 10.4

90.04 ± 12.6

0.42

99.89 ± 14

93.26 ± 9

0.002**

Waist (cm)

113.38 ± 9.6

107.66 ± 11

< 0.001**

107.82 ± 12

100.5 ± 11.3

< 0.001*

BMI (kg/m2)

33.7579 ± 4

32.0069 ± 4

0.004**

35.4 ± 5.4

32.3 ± 4.2

< 0.001*

SBP (mmHg)

151.08 ± 18

140.44 ± 15

< 0.001**

155 ± 18

145.97 ± 15

0.001**

DBP (mmHg)

94.85 ± 15

86.41 ± 10

< 0.001**

97.45 ± 15

90.48 ± 11

0.002**

FBS (mg/dL)

202.02 ± 49

210.70 ± 62

0.323

94.04 ± 21

92.8 ± 21.5

0.711

2HPP (mg/dL)

236.308 ± 70

249.437 ± 88

0.258

101.63 ± 20

100 ± 19.3

0.646

HbA1c %

8.3077 ± 1.5

8.3511 ± 1.5

0.85

5.761 ± 0.8

5.6 ± 0.74

0.055

CHOL (mg/dL)

220.462 ± 49

201.852 ± 52

0.017*

227.4 ± 65

202.78 ± 58

0.01*

TG (mg/dL)

184.015 ± 35

196.230 ± 87

0.161

183.61 ± 61

166.58 ± 64

0.091

HDL (mg/dL)

31.677 ± 7.5

35.859 ± 9.0

0.002**

33.14 ± 9.5

33.19 ± 9.2

0.974

LDL (mg/dL)

152 ± 51.5

124.519 ± 47

< 0.001**

157.07 ± 61

135.17 ± 56

0.017*

CRP (mg/L)

124.7 ± 55

113.7 ± 61

0.221

129.82 ± 42

116.8 ± 47

0.076

INS (mIU/L)

10.8 ± 28

11.58 ± 23.0

0.828

12.18 ± 16

14.6 ± 16.7

0.34

PON1 (mIU/mL)

22.75 ± 7.2

27.3 ± 14

0.021*

25.87 ± 6

25.8 ± 8

0.993

  1. CAD with T2DM CAD with type 2 diabetes mellitus, CAD coronary artery diseases, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, FBS fasting blood sugar, 2HPP 2 h post prandial, HbA1c hemoglobin A1c (glycated hemoglobin), CHOL cholesterol, TG triglyceride, HDL high-density lipoprotein, LDL low-density lipoprotein, CRP c-reactive protein, INS insulin, PON1 paraoxonase 1
  2. *The mean difference is significant at the 0.05 level (two-tailed)
  3. **The mean difference is highly significant at the 0.01 level (two-tailed)