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Table 2 Prophylactic and therapeutic effect of chitosan on activities of the antioxidants against Li2CO3-induced renal toxicity in rats

From: A renoprotective role of chitosan against lithium-induced renal toxicity in rats

  C CS Li Pre-treated Sim-treated Post-treated
SOD (U/g protein) 0.86 ± 0.01 0.82 ± 0.01 0.48 ± 0.01a 0.80 ± 0.01b 4.20 ± 0.02ab 4.12 ± 0.05ab
CAT (k/g protein) 556.28 ± 1.77 551.03 ± 1.41 348.17 ± 3.36a 550.47 ± 0.73b 370.47 ± 1.94ab 379.82 ± 2.83ab
Gpx (U/g protein) 569.48 ± 1.12 572.33 ± 0.96 335.21 ± 1.44a 567.30 ± 1.22b 325.50 ± 1.07ab 329.89 ± 1.04ab
GSH (μmol/mg protein) 3.93 ± 0.06 3.83 ± 0.03 1.88 ± 0.02a 3.78 ± 0.05b 1.87 ± 0.06a 2.21 ± 0.05ab
  1. Values are expressed as mean ± SE for 8 rats per group
  2. aStatistically difference in comparison with control group (significant at P < 0.05)
  3. bStatistically difference in comparison with Li-treated group (significant at P < 0.05)