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Table 2 Prophylactic and therapeutic effect of chitosan on activities of the antioxidants against Li2CO3-induced renal toxicity in rats

From: A renoprotective role of chitosan against lithium-induced renal toxicity in rats

 

C

CS

Li

Pre-treated

Sim-treated

Post-treated

SOD (U/g protein)

0.86 ± 0.01

0.82 ± 0.01

0.48 ± 0.01a

0.80 ± 0.01b

4.20 ± 0.02ab

4.12 ± 0.05ab

CAT (k/g protein)

556.28 ± 1.77

551.03 ± 1.41

348.17 ± 3.36a

550.47 ± 0.73b

370.47 ± 1.94ab

379.82 ± 2.83ab

Gpx (U/g protein)

569.48 ± 1.12

572.33 ± 0.96

335.21 ± 1.44a

567.30 ± 1.22b

325.50 ± 1.07ab

329.89 ± 1.04ab

GSH (μmol/mg protein)

3.93 ± 0.06

3.83 ± 0.03

1.88 ± 0.02a

3.78 ± 0.05b

1.87 ± 0.06a

2.21 ± 0.05ab

  1. Values are expressed as mean ± SE for 8 rats per group
  2. aStatistically difference in comparison with control group (significant at P < 0.05)
  3. bStatistically difference in comparison with Li-treated group (significant at P < 0.05)