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Table 3 Correlation between the duration of drug therapy and level of glutathione-S-transferase and malondialdehyde in the epileptic groups

From: Influence of conventional antiepileptic drugs on glutathione-S-transferase and lipid peroxidation in children with idiopathic epilepsy

Group

MDA

(nmol/mL)

GST

(U/l)

Group A

r

0.663

− 0.730

p value

0.001

0.001

Group B

r

0.621

− 0.749

p value

0.003

0.001

Group C

r

0.840

− 0.917

p value

0.002

0.001

  1. Group A: patients on valproate monotherapy
  2. Group B: patients on carbamazepine monotherapy
  3. Group C: patients on valproate and carbamazepine
  4. MDA malondialdehyde, GST glutathione-S-transferase