Table 3 Detail of VCAN-targeted drugs from CTD's gene–drug interaction network
Chemical name | Chemical ID | Interaction |
|---|---|---|
bisphenol A | C006780 | Bisphenol A results in increased methylation of VCAN gene |
Benzo(a)pyrene | D001564 | Benzo(a)pyrene results in increased methylation of VCAN exon |
Benzo(a)pyrene | D001564 | Benzo(a)pyrene results in increased methylation of VCAN promoter |
Benzo(a)pyrene | D001564 | Benzo(a)pyrene results in increased mutagenesis of VCAN gene |
CGP 52608 | C092451 | CGP 52608 promotes the reaction [RORA protein binds to VCAN gene] |
Aflatoxin B1 | D016604 | Aflatoxin B1 results in increased methylation of VCAN intron |
Sodium arsenite | C017947 | Sodium arsenite affects the methylation of VCAN gene |
Vehicle emissions | D001335 | Vehicle emissions results in increased methylation of VCAN gene |